A 20-year-old woman with systemic lupus erythematosus presented with generalized edema and nephrotic range proteinuria. A renal biopsy revealed diffuse foot process effacement without significant glomerular immune deposits, which was compatible with minimal-change nephrotic syndrome. The diagnosis of lupus podocytopathy was made and high-dose prednisolone was started. After prednisolone therapy, the generalized edema and proteinuria improved.
Biopsy ; Edema ; Female ; Foot ; Humans ; Lupus Erythematosus, Systemic ; Nephrosis, Lipoid ; Nephrotic Syndrome ; Podocytes ; Prednisolone ; Proteinuria ; Young Adult