1.Correlation between interleukin-10 and T regulatory cells in leprosy patients
Caixia LI ; Lin LU ; Xiaohong ZHOU ; Zihong ZOU ; Yuanpin XU ; Xiaolin WANG ; Wenli DING ; Xiaohong ZHANG ; Xiaolan LI
Chinese Journal of Immunology 2014;(8):1105-1107
To detect the correlation between Interleukin-10 and CD4+CD25+Foxp3+regulation T cells ( Treg) and to explore the significance and mechanism of them in leprosy patients.Methods:We used the cytometric bead arra (CBA) to detect the serum Interleukin-10 in 30 leprosy patients and we used flow cytometry to test the Treg cells in 51 leprosy persons.Results:The con-centration of serum IL-10 in leprosy patients(130.00±54.27)pg/ml was higher than normal people(15.64±7.11)pg/ml,(P<0.05);The percentage of Treg cells in leprosy patients(17.626±8.1977)%was higher than normal people(9.998±1.7062)%,(P<0.05).The relevance between IL-10 and Treg is positive and linear ,( P<0.05 ).Conclusion: The imbalance between IL-10 and Treg cells may lead to immune abnormal in leprosy patients.
2.A preliminary exploration of fluid resuscitation during the shock stage of mass burn patients.
Shaopu CAI ; Qingyi ZHENG ; Jinhe CHEN ; Linbizhen CAI ; Zihong ZOU
Chinese Journal of Burns 2002;18(4):223-225
OBJECTIVETo explore the effects of fluid resuscitation during the shock stage of mass burn patients.
METHODSEleven major burn patients out of 25 were rescued at spot and were resuscitated. The treatment results were analyzed and concluded.
RESULTSThe eleven patients were all cured by smoothly living through the shock stage.
CONCLUSIONThe approaching of medical personnel to the site might be the guarantee of correct and timely fluid resuscitation during shock stage, which could be effective on the prevention of burn shock development.
Adult ; Burns ; therapy ; Humans ; Resuscitation ; Shock ; therapy