Upper urinary tract calculi combined with dual infections is rare, and the antimicrobial therapy is complicated. This retrospective study analyzed the clinical data of 3 patients with upper urinary tract calculi combined with dual infection who were admitted to our hospital. Three patients were treated with piperacillin sulbactam combined with fluconazole for 1 week, according to the preoperative urine culture and drug sensitivity results. Endoscopic surgery was performed after the efficacy was determined by routine urine examination. After surgery, fluconazole was administered until the removal of the double-J tube for 2 weeks, and fluconazole was discontinued when no white blood cells or fungus were found. No recurrence of stones or infection was observed at a follow-up of 11 months to 2 years. The rational choice of antimicrobial drugs to treat upper urinary tract calculi combined with dual infection could create good conditions for endoscopic surgical intervention, thus achieving satisfactory clinical outcomes.

Objective To explore the effect of early pressure therapy during sensory training on functional recovery after island skin flap repairing vitia of thumb ventral. Methods From January, 2016 to July, 2017, 63 patients accepted island skin flap repairing vitia of thumb ventral were divided into control group (n=31) and observation group (n=32) according to the order of hosptalization. The control group accepted routine sensory training, while the observation group accepted early pressure therapy in addition. Their swelling, scars and sensory function were observed after treatment. Results The swelling and scars were milder, and the sensory function was better in the observation group than in the control group (P<0.05).Conclusion Combination with early pressure therapy during sensory training may promote the recovery of sensory function and fadeaway of swelling, and alleviate the formation of scar.