1.Clinical features and left ventricular (LV) dysfunction in heart failure patients with normal ejection fraction
Shaohua LIN ; Ling JIANG ; Yansong JU ; Zidong TANG
Chinese Journal of General Practitioners 2011;10(1):45-47
100 inpatients with heart failure were divided into two groups: 50 with preserved LVEF and 50 with reduced LVEF. Another 50 age-matched healthy subjects served as the control group. The severity and etiology of heart failure, tissue Doppler imaging indexes (Sm;Ea;Aa;E/Ea) and plasma BNP concentrations were compared among the three groups. There was no difference in terms of NYHA classification between groups of preserved LVEF and reduced LVEF. Hypertension and DM are more common in the group of preserved LVEF. The index of Sm decreased most significantly in the group of reduced LVEF, and was negatively correlated with the BNP concentration (r = -0. 35, P < 0. 05 ). The ratio of E/Ea increased gradually among the three groups, and was positively correlated with the BNP concentration ( r = 0. 728, P < 0. 05 ). The LV filling index E/Ea and the BNP concentration may be helpful in the diagnosis of heart failure patients with preserved LVEF.
2.Diagnosis and surgical management of tumors primarily in the pterygopalatine fossa
Bojun WEI ; Hong SHEN ; Xiaoli ZHU ; Peihong PENG ; Xiuzhen SHI ; Baoquan ZHANG ; Zidong JIANG ; Xiuqing BAI ; Shuhua YANG
Chinese Archives of Otolaryngology-Head and Neck Surgery 2006;0(06):-
OBJECTIVE To evaluate the clinical features of tumors primarily in the pterygopalatine fossa, and the efficiency of surgical management for these lesions. METHODS The clinical data of 7 cases with tumors primarily in the pterygopalatine fossa were retrospectively studied. Three of them were primary diseases, i.e. fibrous histiocytoma, neurofibroma and cholesteatoma. The other 4 cases were secondary tumors mainly located in pterygopalatine fossa. There were 1 case with epithelial-myoepithelial carcinoma, 1 case with adenoid cystic carcinoma , 1 case with recurrent inverted nasal papilloma, 1 case with recurrent malignant fibrous histiocytoma. Approaches to tumors in pterygopalatine fossa lesions included lateral rhinotomy, and transnasal or transantrum approaches under the nasal endoscope. RESULTS The patient suffered from adenoid cystic carcinoma developed local recurrence 4 months after operation, and extended resection of the recurrent tumor with laser was performed again. No further recurrence was found after following-up for 3 years. Neither local recurrence nor regional metastasis was found in the remaining 6 cases with a follow-up period of 2 to 4 years. The main complication was oronasal fistula. CONCLUSION CT scan or MRI is the main method to the early diagnosis of pterygopalatine fossa tumors. Lateral rhinotomy, endoscopic trasnnasal or transantrum approaches are feasible procedures to resect the tumors.
3.Multidisciplinary cooperation in the diagnosis and treatment of vertigo/dizziness
Chinese Journal of Neurology 2019;52(2):153-156
There are many subjects for the diagnosis and treatment of vertigo/dizziness.Only by standardized diagnosis and treatment can we avoid misdiagnosis and mistreatment.First,terminology standardization should be applied,including how to interpret sudden hearing loss,vestibular migraine and benign paroxysmal positional vertigo to Chinese nomenclature and to describe deafness and hearing loss correctly.Second,the key points of differential diagnosis of central and peripheral vestibular diseases must be accurately grasped,conducting clinical work under the guidance and consensus of diagnosis and treatment of relevant vestibular diseases and mastering the new concepts and new developments at home and abroad in order to promote the level of the diagnosis and treatment of vertigo/dizziness.
4.Numerical study on the effect of the geometry size of multi-chamber infusion bag on its bursting force.
Zidong FAN ; Guanshi WANG ; Huaijun YUE ; Wentao JIANG ; Zhenting DU ; Hongbo TAN ; Wenjun LIU
Journal of Biomedical Engineering 2021;38(4):716-721
This study explored the variation of bursting force of multi-chamber infusion bag with different geometry size, providing guidance for its optimal design. Models of single-chamber infusion bag with different size were established. The finite element based on fluid cavity method was adopted to calculate the fluid-solid coupling deformation process of infusion bag to obtain corresponding critical bursting force. As a result, we proposed an empirical formula predicting the critical bursting force of one chamber infusion bag with specified geometry size. Besides, a theoretical analysis, which determines the force condition of three chamber infusion bag when falling from high altitude, was conducted. The proportion of force loaded on different chamber was gained. The results indicated that critical bursting force is positively related to the length and width of the chamber, and negatively related to the height of the chamber. While the infusion bag falling, the impact force loaded on each chamber is proportional to the total liquid within it. To raise the critical bursting force of in fusion bag, a greater length and width corresponding to reduced height are recommended considering the volume of liquid needed to be filled in.