1.Comparison of three types of china donation after citizen's death in clinical efficacy and complications after liver transplantation: a report of 422 cases
Qifa YE ; Qianchao HU ; Yingzi MING ; Yanfeng WANG ; Ke CHEN ; Shaojun YE ; Guizhu PENG ; Zibiao ZHONG ; Yi ZHANG ; Zhiliang WANG ; Yujun ZHAO ; Jing SI
Chinese Journal of Organ Transplantation 2017;38(7):408-413
Objective To compare three different types of donor livers (C-Ⅰ,C-Ⅱ,C-Ⅲ) in clinical efficacy,complications and survival rate of liver transplantation.Methods Using the retrospective descriptive study method,the clinical data of 422 patients undergoing liver transplantation,including 124 cases of C-Ⅰ,81 cases of C-Ⅱ and 81 cases of C-Ⅲ in recent 6 years (from June 2010 to June 2016) were analyzed.The same surgical method was performed with piggyback liver transplantation.Observation indicators contained (1) recipient postoperative liver function;(2) the postoperative complications;(3) the recipient survival rate.SPSS 19.0 statistical software was used for analysis.Results (1) The curative effect was evaluated by the changes of ALT and TBIL among three groups of recipients postoperatively.As compared with C-Ⅰ transplantation group and CⅢ transplantation group,the level of ALT in C-Ⅱ transplantation group was significantly increased (P <0.05),the clinical efficacy was poorer.(2) The incidence of PNF was 3.23% in C-Ⅰ group,9.88% in C-Ⅱ group and 9.88% in C-Ⅲ group (P<0.05).The incidence of acute rejection was respectively 9.68% in C-Ⅰ group,38.27% in C-Ⅱ group and 38.27% in C-Ⅲ group (P<0.001).The incidence of SIRS was respectively 5.65% in C-Ⅰ group,39.50% in C-Ⅱ group and 39.50% in C-Ⅲ group (P< 0.001).There were significant differences in the incidence of other complications among the three groups.(3) There were 14 deaths within 3 months,accounting for 17.28%,and the survival rate was 82.72% in C-Ⅱ group,the 1-,3-,and 5-year survival rate was 76.55%,74.18% and 76.55% respectively in C-Ⅰ group,and that was 88.02%,85.72% and 81.11% respectively in C-Ⅲ group.Conclusion Since June 2015,C-Ⅰ donors grow up more quickly on year-on-year basis than C-Ⅱ.Simultaneously,the sort-term and long-term clinical efficacy is better in C-Ⅰ transplantation group than in C-Ⅱ transplantation group.How to repair the three types of Chinese standard donor organs and optimize the quality is still a hot point to ensure the healthy development of organ transplantation in China,which needs further investigation.
2.Application effect of modified installing method of high flexion rotating platform prosthesis trial model in double compartment knee arthroplasty
Zibiao ZHAO ; Junfu DUAN ; Xuguang CHENG ; Chao SUN ; Yunjing LI ; Zilu QIN ; Bo WANG
Journal of Xinxiang Medical College 2023;40(12):1136-1139
Objective To explore the application effect of modified installing method of high flexion rotating platform prosthesis trial model in double compartment knee arthroplasty.Methods A total of 20 patients(26 knees)with severe knee osteoarthritis admitted to Hebi People's Hospital from January 2021 to April 2022 and required double compartment knee arthroplasty were selected as the research subjects.Patients were divided into the control group(10 knees)and the observation group(16 knees)based on the installing method of high flexion rotating platform prosthesis trial model.The patients in the control group used the conventional installing method of high flexion rotating platform prosthesis test model(placing the tibial side test model,the femoral side test model and finally the pad test model),while patients in the observation group used the modified installing method of high flexion rotating platform prosthesis test model(matching the femoral test model,pad and tibial test model when the patient flexed 60° to 90°,and placing them together into the knee joint osteotomy groove).The intraoperative bleeding volume and surgical time of patients in the two groups were recorded.Before surgery,2 weeks after surgery and 18 months after surgery,the knee joint function of patients was evaluated by the American hospital for special surgery(HSS)scoring system,and the range of motion(ROM)of knee joint of patients was measured by protractor.Results The intraopera-tive bleeding volume of patients in the observation group was significantly less than that in the control group,and the surgical time was significantly shorter than that in the control group(P<0.05).There was no statistically significant difference in preoperative HSS score and ROM of knee joint of patients between the two groups(P>0.05).At 2 weeks and 18 months after surgery,the HSS score and ROM of knee joint of patients in the observation group were significantly higher than those in the control group(P<0.05).Conclusion Compared with the conventional installing method of high flexion rotating platform prosthesis trial method,the modified installing method of high flexion rotating platform prosthesis trial model in double compart-ment knee arthroplasty for patients with severe knee osteoarthritis can effectively improve surgical efficiency,reduce intraopera-tive bleeding,improve knee function and increase ROM of knee joint.