1.Current progress in research on animal model of retinal vein occlusion
Chinese Journal of Experimental Ophthalmology 2012;(11):1044-1047
Retinal vein occlusion(RVO) is a common retinal vascular disorder that frequently leads to severe vision loss and even blindness due to its complications,such as macular edema and neovascular glaucoma.It is the second leading cause of vascular eye disease behind only diabetic retinopathy.Currently there still is no definite efficacy in treatment for this disease.Researches showed that this disease is a multi-factor and link pathogenic process.Animal models could be potentially of helpful for researching the etiology,pathology and developing new treatments.This paper summarizes the different manufacture methods of the animal models,discusses the pathological changes and chooses the appropriate animal models for different research purposes and offers a good experimental basis to develop new treatments.
3.Determination of Lipoprotein Lipase and Hepatic Lipase in Children with Nephrotic Syndrome
Journal of Applied Clinical Pediatrics 1992;0(05):-
Objective To investigate pathogenesis of liprd metabolism disorder in children with nephrotic syndrome. Methods Serum lipid and plasma llpoprotein lipase and hepatic lipase were detected in 62 nephrotic syndrome children and 30 normal children, respectively. Results The activity of lipoprotein lipase and hepatic lipase was lower than that in normal control group, while serum cholesterol, triglycerides and low -density lipoprotein in nephrotic group were higher than those in control group. Lipoprotein lipase and hepatic lipase were negative correlation with triglycerides and low - density lipoprotein, respectively. Conclusions Reduced activity of lipoprotein lipase and hepatic lipase is one of causes leading to hypertriglyceridemia in nephrotic syndrome.
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