Dendritic cells are the most powerful cells to induce T cell immune reaction. DC derived from leukemia also possess the ability of the antigen processing and presentation. DC pulsed with tumor antigen can effectively initiate T cell immune reaction and induce T cell to cytotoxic T lymphocytes in vitro and in vivo. In this text, we introduce the advanced development of the biological character of DC, tumor immunology, the mechanism of tumor cell escaping immune surveillance and DC in leukemia immunotherapy.

To establish the evaluation system for Guinea pig skin infection model of Trichophyton rubrum, and to evaluate different modeling methods and select the best skin infection animal model of Trichophyton rubrum. Methods The evaluation index was determined by literature research and expert consultation , weight of each index was calculated by Delphi Method and the analytic hierarchy process (AHP), to establish a comprehensive evaluation system for Guinea pig skin infection model of Trichophyton rubrum. Furthermore, various skin infection animal models of Trichophyton rubrum were evaluated by this system and the ideal animal model was selected. Results The evaluation system proved to be available. The animal model with immunosuppressive treatment and repeated inoculation with Trichophyton rubrum had better quality and higher success rate. Conclusions The evaluation system established by AHP is clear, simple and convenient; the optimized skin infection animal model of Trichophyton rubrum is suitable for the efficacy evaluation of antifungal infection drugs.

Antineoplastic Agents ; administration & dosage ; adverse effects ; therapeutic use ; Asparaginase ; administration & dosage ; adverse effects ; therapeutic use ; Child ; Drug Administration Routes ; Drug Administration Schedule ; Forecasting ; Humans ; Leukemia ; drug therapy ; Precursor Cell Lymphoblastic Leukemia-Lymphoma ; drug therapy

Audiology ; China ; Congresses as Topic ; Humans ; Vestibular Diseases

Electronystagmography ; Humans ; Postural Balance ; Vestibular Function Tests

Adult ; Carotid Body Tumor ; complications ; Female ; Glomus Jugulare Tumor ; complications ; Humans

Cystic Adenomatoid Malformation of Lung, Congenital ; diagnostic imaging ; pathology ; surgery ; Female ; Follow-Up Studies ; Humans ; Infant, Newborn ; Lung ; diagnostic imaging ; pathology ; Male ; Pneumonectomy ; Tomography, X-Ray Computed

BACKGROUND:Calcium phosphate has the similar mineral component of natural bones with good bioactivity, osteoconductivity and degradability. It has been widely used in bone defect repair and coatings of implants. OBJECTIVE:To review the major properties of different-phase calcium phosphate and to summarize the application of calcium phosphate in scaffolds for osteochondral tissue engineering. METHODS:A computer-based search of PubMed, CNKI and VIP database was performed for relevant articles published from January 2000 to February 2015 with the key words of “osteochondral; calcium phosphate (including hydroxyapatite, tricalcium phosphate, calcium polyphosphate); tissue engineering” in Chinese and English, respectively. RESULTS AND CONCLUSION:Since the calcium phosphate has a variety of phases and crystaline types, a variety of materials with different structure and size can be obtained using different techniques, such as hydroxyapatite, tricalcium phosphate, calcium polyphosphate, amorphous calcium phosphate. These materials have some differences in their biological and mechanical properties, and hydroxyapatite is the most widely used. Biocomposite scaffolds with calcium phosphates appeared to have promising potential in osteochondral tissue engineering.

Air ; analysis ; Air Pollutants, Occupational ; analysis ; Chromatography, Gas ; methods ; Octanes ; analysis ; Workplace