1.Maternal health information needs in different periods in online maternal-infant forums
Zhuoma RENQING ; Shiqi WANG ; Xiaoni HOU ; Hongmei DUAN
Chinese Journal of Modern Nursing 2022;28(16):2121-2125
Objective:To explore the information needs of pregnant and lying-in women in the maternal-infant forums, so as to provide theoretical basis and information support for the development of maternal health education.Methods:From July 1 to 31, 2020, the question texts in the three major sections of pregnancy preparation, pregnancy, and lactation in the "Mama.com" Q&A column were used for data cleaning and word segmentation, and the Latent Dirichlet Allocation (LDA) model was used to mine topic features.Results:The analysis of the subject characteristics of the question records of "Mama.com" showed that the LDA model divided 32 466 question records into 3 stages and a total of 10 subjects, namely the pregnancy preparation (pre-pregnancy health knowledge needs, emotional characteristics during pregnancy preparation, second child preparation, assistance reproduction) , pregnancy (first trimester, second trimester, third trimester, childbirth) , lactation (feeding knowledge needs, baby care needs) .Conclusions:The research results based on the LDA model can reflect the information needs of pregnant and lying-in women in online maternal-infant forums, and provide information guidance and emotional support for maternal knowledge and special emotional needs of pregnant and lying-in women in different periods.
2.Quality Assessment of Different Sources of Tibetan Medicine "Jiawa" Based on Antioxidant Activity Spectrum-effect Relationship
nanjia Cairang ; zhuoma Xiangcuo ; renqing Duojie
Chinese Journal of Modern Applied Pharmacy 2024;41(12):1686-1693
OBJECTIVE
To evaluate the quality of different sources of Tibetan medicine "Jiawa" by the spectrum-effect relationship.
METHODS
The HPLC fingerprints of 17 batches of "Jiawa" were analyzed by similarity evaluation, cluster analysis and principal component analysis. Gray correlation degree analysis was used to study the relationship between 13 common fingerprint peaks and DPPH/ABTS radical scavenging capacity of "Jiawa". Due to high correlation with antioxidant activity, the content of ferulic acid was determined.
RESULTS
The 17 batches of "Jiawa" samples showed varied greatly in fingerprint characteristics, antioxidant activity and content of ferulic acid, which divided into group A and group B. Osmorhiza aristata (group A) showed low similarity in both chemical components and concentration with other samples, should not be used as "Jiawa". Group B included mainstreaming "Jiawa" products in the market(Pleurospermum hookeri, Pleurospermum szechenyii, Vicatia thibetica, Sphallerocarpua gracilis), showed some difference within group. Vicatia thibetica from Linzhi showed the best antioxidant activity and the highest of ferulic acid, while those from Lhasa and its surrounding areas had good antioxidant activity, and the ferulic acid content was moderate. Samples from Aba and Changdu had the minimum level in both antioxidant activity and ferulic acid content.
CONCLUSION
Ferulic acid is closely related to the antioxidant capacity of "Jiawa", which can be used as an important target to evaluate the quality of Tibetan medicine "Jiawa".