1.Prediction of core behaviors of self-management in diabetes mellitus by empowerment and theory of planned behavior
Fangli TANG ; Wenjun WANG ; Jiaohong LUO ; Danyu ZHANG ; Leilei ZHU ; Zhumin JIA ; Huanhuan LIU ; Qingqing LOU
Chinese Journal of Diabetes 2024;32(10):750-755
Objective To explore the predictive effect of empowerment and theory of planned behavior(TPB)on the four core behaviors of type 2 diabetes mellitus(T2DM)self-management,and analyze the influence path of TPB model and behavioral intention on the four core behaviors.Methods A total of 500 T2DM patients who were hospitalized in the Endocrinology Department of three tertiary general hospitals in different provinces from December 2022 to May 2023 were selected for investigation.Hierarchical multiple regression analysis was used to explore the predictive effects of empowerment and TPB models on self-management behaviors.Bootstrap method was used to analyze the influence path of TPB model and behavior intention on self-management behaviors.Results Empowerment had a predictive effect on self-management behavior,which was improved after the addition of TPB,with medication R2=0.194,blood glucose monitoring R2=0.308,regular diet R2=0.337 and regular exercise R2=0.343,respectively.Mediation effect analyses revealed that attitude,subjective norm,and perceived behavioral control were observed to predict behavior intention across the four behaviors,and the three except through the behavior intention indirectly affect behavior,can also directly affect the behavior.Conclusions Empowerment can predict self-management behavior,and adding TPB to this can improve the prediction effect.Attitude,subjective norms and perceived control can indirectly or directly affect self-management behavior through behavioral intention.
2.Report of a pedigree of mitochondrial diabetes mellitus complicated with chronic hereditary pancreatitis
Huifang PENG ; Liujun FU ; Kunmu YANG ; Jun QIANG ; Diansen CHEN ; Jie LIU ; Zhumin JIA ; Yingyu ZHANG ; Keyan HU ; Hongwei JIANG
Chinese Journal of Endocrinology and Metabolism 2021;37(8):752-756
This study reported a family of mitochondrial diabetes mellitus complicated with chronic hereditary pancreatitis. A 18-year-old woman presented with self-reported hyperglycemia and chronic epigastric pain was admitted to our hospital. Clinical data and family history were collected. Mitochondrial gene sequencing and whole exon gene sequencing showed that the proband carried mutation of mt.3243A>G and heterozygous mutation of SPINK1 c. 194+ 2T>C, which was considered as mitochondrial diabetes mellitus with chronic pancreatitis.