Objective To analyze clinical effect of treatment for obesity hypertension with western medicine and Zhong Yao Wai Yong Tong Shui San,to provide a reference for clinical drugs.Methods 150 obesity hyperten-sion patients were selected,they were divided into group A,B,C according to mathematical random method,50 cases in each group.Ammonia amlodipine was used in group A,dimethyl biguanide was used in group B,besides ammonia amlodipine and dimethyl biguanide,self-made Zhong Yao Wai Yong Tong Shui San were used in group C.Index such as insulin and blood pressure were compared in three groups.Results Rate of blood pressure control of group C was 96.00%,higher than that of group A (80.00%)and group B (82.00%),there were statistical difference (χ2 =6.495,P=0.008;χ2 =6.215,P=0.010);after the treatment,DBP and SBP of group C were (73.75 ±6.83)mmHg and (122.66 ±11.46)mmHg,better than group A and group B(all P<0.05);decrease of TC,TG,HDL-C,LDL-C of group B were better than group A(all P<0.05),but group C was better than group A(P<0.05);decrease results of insulin was group C >group B >group A,there were statistical difference (all P <0.05 ).Conclusion Combination of western medicine and Zhong Yao Wai Yong Tong Shui San has a good performance in improving blood pressure,blood lipids and insulin.

Objective To learn therapeutic effect of the combined treatment of mecobalamin and salvia milti-orrhiza ligustrazine on diabetic peripheral neuropathy.To provide effective and reliable operation method for the treat-ment of disease.Methods 163 cases with diabetic peripheral neuropathy were randomly divided into observation group(86 cases)and control group(77 cases).The observation group was treated with mecobalamin combined salvia miltiorrhiza ligustrazine,the control group was treated with mecobalamin.The sensory conduction velocity (SNCV) and motor conduction velocity (MNCV)were measured in the two groups before and after treatment.The therapeutic effects were evaluated after one course.Results The MNCV and SNCV of the two groups were higher than before treatment,the difference was statistically significant (t =24.298,25.546,18.737,15.733,14.284,14.886,9.337, 9.402,all P <0.05).The SNCV and MNCV in the observation group were significantly higher than those in the con-trol group (t =9.119,11.103,7.429,6.352,all P <0.05).The markedly effective rate of the observation group was 48.8% (42 /86),the total effective rate was 90.7% (78 /86),which were higher than those of the control group,the differences were statistically significant (χ2 =9.010,7.937,all P <0.05).The incidence rate of adverse reaction of the observation group was 5.8% (5 /86),which of the control group was 6.5% (5 /77),the difference was not statis-tically significant (χ2 =0.033,P >0.05).Conclusion In the treatment of diabetic peripheral neuropathy,the com-bined treatment of mecobalamin and salvia miltiorrhiza ligustrazine has better curative effect and low incidence rate of adverse reaction,with good clinical application value.