1.Design of an embedded stroke rehabilitation apparatus system based on Linux computer engineering.
Pengfei ZHUANG ; XueLong TIAN ; Lin ZHU
Journal of Biomedical Engineering 2014;31(2):288-292
A realizaton project of electrical stimulator aimed at motor dysfunction of stroke is proposed in this paper. Based on neurophysiological biofeedback, this system, using an ARM9 S3C2440 as the core processor, integrates collection and display of surface electromyography (sEMG) signal, as well as neuromuscular electrical stimulation (NMES) into one system. By embedding Linux system, the project is able to use Qt/Embedded as a graphical interface design tool to accomplish the design of stroke rehabilitation apparatus. Experiments showed that this system worked well.
Biofeedback, Psychology
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Computers
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Electric Stimulation Therapy
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instrumentation
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Electromyography
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Equipment Design
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Humans
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Software
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Stroke Rehabilitation
2.The prognostic value of baseline serum free light chain in cardiac amyloidosis
Lei ZHAO ; Zhuang TIAN ; Quan FANG
Chinese Journal of Internal Medicine 2016;55(3):186-190
Objective To analyze the prognostic value of baseline serum free light chain (sFLC) in light-chain (AL) cardiac amyloidosis.Methods Twenty-seven patients with AL cardiac amyloidosis were retrospectively reviewed from January 2014 to January 2015.sFLC was measured by immuoturbidimetric assay.Baseline characteristics,echocardiographic parameters and electrocardiogram data were analyzed.According to the median baseline dFLC (involved sFLC minus uninvolved sFLC),patients were categorized into either the low dFLC(≤307mg/L) or the high dFLC group (>307mg/L).Results More subjects in the high dFLC group with early/late diastolic mitral velocity ratio (E/A ratio) over 2 (71.4% vs 30.8%,P =0.035),and subjects in this group had a shorter median survival time than those in the low dFLC group (3 months vs 17 months,P =0.004).A similar phenomenon for median survival time was observed when the subjects were redivided either by a new cut-off value of 180mg/L for dFLC (low dFLC group:17 months;high dFLC group:4 months,P =0.014) or a κ/λ ratio,in which subjects with κ type sFLC-ratio ≤ 19.6 and λ type sFLC-ratio >0.065 were in the low sFLC-ratio group (17 months) and those with κ type sFLC-ratio > 19.6 and λ type sFLC-ratio ≤0.065 were in the high sFLC-ratio group (4 months,P=0.023).In multivariate analysis,dFLC and New York Heart Association (NYHA) classification of cardiac function were two risk factors associated with all-cause mortality in patients,among which the hazard ratio for higher dFLC was 4.28 (95% CI 1.55-11.8,P =0.005).Conclusion The level of sFLC could be a marker for the prognosis of AL cardiac amyloidosis.
3.Clinical features of acute myocardial infarction in young female patients
Zhuang TIAN ; Ran TIAN ; Zhenyu LIU ; Yong ZENG ; Shuyang ZHANG
Chinese Journal of Interventional Cardiology 2014;(5):295-299
Objective To investigate the clinical features of young female patients with acute myocardial infarction (AMI) who were referred to Peking Union Medical College Hospital. Methods A total of 24 consecutive AMI female patients (age≤44 years) who underwent coronary angiography were retrospectively retrieved from the database, and 70 AMI patients whose age ≥ 65 years and who also underwent coronary angiography were enrolled as a control (elderly) group. Clinical features were compared between the two groups. Results Of the 24 young female AMI patients, MI from non-atherosclerosis was identiifed in 9 patients (non-ATS group). Compared to the remaining 15 young female AMI patients (ATS-group), non-ATS group was younger (P<0.05), with lower BMI (P<0.05) and less traditional risk factors of coronary heart disease (P<0.05). Coronary angiography showed more normal artery (P<0.05) and lesions on left main (P<0.05). However, when compared to the elderly group, the young female ATS-group was associated with less hypertension (P<0.01), smoking (P<0.05), traditional risk factors (P<0.01) and lower level of blood pressure (P<0.05), fasting glucose (P<0.05), serum creatine (P<0.01), TC (P<0.05), and LDL-C (P<0.01) at admission. Coronary angiography showed single vessel disease was the most common lesion. Conclusions Acute myocardial infarction in young female might be caused by non-atherosclerosis. Those due to atherosclerosis differ in coronary risk factors and angiographic features from the elderly female AMI patients.
4.Report of epidermal growth factor receptor mutation in a patient with combined small cell lung cancer.
Haiying WANG ; Zhuang TIAN ; Yabin ZOU ; Lizhi HAN ; Xiumei DUAN
Chinese Journal of Pathology 2014;43(1):45-46
Adenocarcinoma
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genetics
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metabolism
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pathology
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Biopsy
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CD56 Antigen
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metabolism
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DNA-Binding Proteins
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metabolism
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Gene Deletion
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Humans
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Keratin-7
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metabolism
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Lung Neoplasms
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genetics
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metabolism
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pathology
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Male
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Middle Aged
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Receptor, Epidermal Growth Factor
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genetics
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metabolism
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Small Cell Lung Carcinoma
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genetics
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metabolism
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pathology
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Synaptophysin
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metabolism
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Transcription Factors
5.PACS evolution in China between 1990-2000 and its prospect.
Chinese Journal of Medical Instrumentation 2002;26(2):82-83
In this paper a brief history of the development of PACS in China is reviewed, the current status of PACS is presented, and its development in the future is discussed.
China
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Humans
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Image Processing, Computer-Assisted
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Medical Records Systems, Computerized
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Radiology Information Systems
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organization & administration
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trends
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Technology, Radiologic
8.Significance produced by examining NSCLC vein formation through enhanced SCT scanning in clinical treatment
Qiang ZHANG ; Chunjing LI ; Zhaoxin LIU ; Zhuang TIAN
Cancer Research and Clinic 2009;21(2):114-116
Objective To evaluate the examination of non-small-cell lung (NSCLC) vein formation and the dynamic characteristics of blood stream through enforced SCT scanning for the research on and clinical diagnosis of tumor.Methods Double period enhanced SCT scanning was done to 152 NSCLC cases identified pathologically.Makes the color coding the tumour blood stream irrigation chart,the analysis blood stream irrigation characteristic.Compare the enforced morphologic manifestation of cancer focus with histology and analyze their pertinence.Results The enforced CT peak value (PV) of the low differentiation is bigger than that of the medium differentiation,which is bigger than the high differentiation.63 cases are 45-70 HU,78 cases are 20-45 HU and 11 cases are 10-20 HU.67 case are of abnormal arteriola; 23 cases are of abnormal hemal sinus development; 35 cases are pistil-like.Conclusion Accurately examining and quantifying cancer focus vein formation according to SCT double period enforced scanning is of high guiding value in the enactment of the plan for treating NSCLC and the comprehensive treatment of tumors.
9.Diagnosis and management of postoperative gastrointestinal bleeding after pancreaticoduodenectomy
Yan ZHUANG ; Xiaodong TIAN ; Guangdong WU ; Weimin WANG ; Yinmo YANG
Chinese Journal of Hepatobiliary Surgery 2012;18(10):765-768
ObjectiveTo analyze the underlying causes of postoperative gastrointestinal (CI)bleeding after pancreaticoduodenectomy and to discuss the strategies in diagnosis,prevention and management.MethodsThe clinical data of 331 patients who were admitted to the Surgical Department of the First Hospital,Peking University from Jan. 1998 to Jan. 2010 was retrospectively analyzed.ResultsThe overall postoperative morbidity was 37.2 %,with a bleeding complication rate of 6.7 %,and a GI bleeding rate of 1.5%.For postoperative GI bleeding,the main bleeding sites were from the pancreaticointestinal anastomosis (40.0%) and the gastrointestinal anastomosis (20.0%). Embolotherapy using vascular intervention alone (20.0%),open abdominal operation following vascular interventional therapy (40.0 % ) and open abdominal operation alone (40.0 % ) were used to control GIbleeding.ConclusionsThe common bleeding sites in the GI tract were at the pancreaticointestinal anastomosis and the gastrointestinal anastomosis. The main procedures used to control bleeding were embolization using vascular interventional therapy,endoscopic therapy and open abdominal therapy.
10.Risk factors for lower extremity lymphedema following treatment of gynecologic cancers:a meta-analysis
Xin CHANG ; Jiaofeng SHEN ; Qiliang PENG ; Zhixiang ZHUANG ; Ye TIAN
Chinese Journal of Radiation Oncology 2017;26(9):1038-1044
Objective To investigate the multiple risk factors for lower extremity lymphedema in patients following treatment of common gynecologic cancers by meta-analysis for systematic analysis and comprehensive quantitative study.Methods Clinical trials published up until August 2016 were retrieved from PubMed, Embase, and the Cochrane Library.The quality of the included studies was assessed by the Newcastle-Ottawa Scale, and data analysis was performed using Stata 14.0 and RevMan 5.3.The strength of the associations between risk factors and gynecologic cancer-related lower extremity lymphedema was described as odds ratio (OR) and 95% confidence intervals (CI).Results Eighteen studies were included in the meta-analysis, and 8 relevant factors were identified.The risk factors for lower extremity lymphedema after treatment of gynecologic cancer mainly included radiotherapy (OR=2.45, 95%CI:2.05-2.95, P=0.000), FIGO stage (OR=2.29, 95%CI:1.66-3.14, P=0.000), and pelvic lymph node dissection (OR=2.00, 95%CI:1.02-3.91, P=0.040).Conclusions Radiotherapy, FIGO stage, and pelvic lymph node dissection are the main risk factors for lower extremity lymphedema after treatment of gynecologic cancers.