ObjectiveTo assess the reliability and validity of the Chinese version of the rejection sensitivity questionnaire(RSQ).Methods813 college students were investigated with RSQ and each caregiver was retested 4 weeks later.Results ( 1 ) All items had good discrimination.(2) Exploratory factor analysis showed the Chinese version of RSQ consisted of three factors which could explain 45.986％ of the total variance.Confirmatory factor analysis indicated that there was high fitting degree between the three-factor model and the two-dimension model.They were significantly correlated with RSQ total score( r =0.661 ～ 0.851,P ＜ 0.001 ).(3) The Cronbach's alpha coefficient was 0.809.The three factor's Cronbach's alphas were 0.684,0.631 and 0.534 respectively.The test-retest coefficient was 0.892 (P ＜ 0.001 ).ConclusionThe Chinese version of RSQ is a reliable and valid measurement for assessing the rejection sensitivity of the Chinese college students.

Objective To explore the application value of CT value histogram in differential diagnosis between primary hepatoma and other space-occupying lesions in liver.Methods From 2012 to 2013,the imaging data in 243 patients with different isolated space-occupying lesions in liver were analyzed retrospectively who underwent both enhanced and unenhanced abdominal CT scans. The lesions were confirmed as hepatic cyst,hepatic hemangioma or primary hepatoma by pathological and other clinical proofs and divided into 3 groups.The histograms of plain scan and post-contrast triphases were drawn respectively using an attached picture-making software.Relevant data of the histograms were analyzed and compared using the SPSS among three groups.Results The CT value histograms of hepatic cysts,hemangiomas and majority of hepatomas presented normal distribution curves.Negative skewness distribution curve was showed in the tumor within necrosis and liquefaction,whereas the positive curve was showed in hepatoma with more calcification.Some significant differences in the Mean,SD,Max,Min,and R values were confirmed.Conclusion Skew-ness distribution curve has a relative high specificity in diagnosis of primary hepatoma.Both dramatic decrease of the Mean value in delayed phase and obvious increase of the R value in plain scan suggest the possibility of primary hepatoma.

Professor Macer summarizes the essence and concepts of bioethics with love as the universal ethical basis,but it effective resources and evidence proves to be limited.In fact,the "love" could be the motive of ethics rather than the basis of ethics.For the origins of ethics are vastly related with compassion and mercy.

Glaucoma is an group of ocular disease associated with the degeneration of retinal ganglion cells and it finally causes vision loss.Primary open angle glaucoma (POAG) is a main type of glaucoma worldwide.The primary reason of POAG is elevated intraocular pressure (lOP) caused by the degeneration or dysfunction of the trabecular meshwork (TM).Recent studies showed that stem cell-based therapy becomes a promising approach to treat the degenerative diseases,including POAG.Among multiple types of stem cells,induced pluripotent stem cell (iPSC) is the one with the most clinical potential due to its autologous derivation and non-ethical issue.In this paper,we summarized the encouraging therapeutic effects of iPSCs on POAG from different species,different etiological factors and different pathological stages.Although these encouraging studies suggest that iPSC is a fabulous stem cell type to regenerate the damaged tissue,more efforts are required for clinical application.In addition,we discussed several solutions to improve the safety of iPSCs and provided potential approaches to improve the therapeutic efficiency and specific targeting.Answering these questions will help us to better understand the characteristics of iPSCs and promote the development of bench to bedside research.

Xinshu (BL 15), Feishu (BL 13), Pishu (BL 20), Ganshu (BL 18), Shenshu (BL23) and Geshu (BL 17) were selected and the needles were retained for 30 min. After the needles were taken out, cupping method was applied on each acupoint. In the treatment of total 36 cases of hyperlipidemia, the results showed remarkable effect in 22 cases, effect in 9cases and failure in 5 cases, and the total effective rate in 86.1%.

Objective To study the factors influencing the assay of ? 1 antitrypsin(? 1 AT) bioactivity. Methods Various concentrations of PEG(MW, 4000), sucrose, sodium citrate and ethanol were added before determining ? 1 AT activity. Results ? 1 AT activity increased approximately 100% compared with the controls when the PEG concentration reached 20%. Conclusion PEG concentration influences the ? 1 AT activity assay.

Adaptor Proteins, Signal Transducing ; genetics ; Bone Marrow Diseases ; genetics ; pathology ; DNA Mutational Analysis ; DNA-Binding Proteins ; genetics ; Exocrine Pancreatic Insufficiency ; genetics ; pathology ; Glucose-6-Phosphatase ; genetics ; Humans ; Leukocyte Elastase ; genetics ; Lipomatosis ; genetics ; pathology ; Mutation ; Neutropenia ; congenital ; genetics ; Proteins ; genetics ; Transcription Factors ; genetics

Since the 1960s,endovascular coil embolization has gradually become another treatment for intracranial aneurysms in addition to craniotomy clipping surgery,and in recent years,it has become the preferred method for many neurologists.However,the complexity of intracranial vascular anatomy and the diversity of intracranial aneurysm make the coil embolization alone unable to meet the needs of all intracranial aneurysms.And then some novel materials and techniques emerged,such as coated coils,balloon-assisted embolization,stent-assisted embolization,and covered stents.The principle of covered stents for the treatment of intracranial aneurysms is to place a kind of stents with bio-physical barriers into the parent arteries,while maintaining the patency of the parent artery,thus isolating aneurysms,leading to thrombogenesis inside and finally curing the lesions while maintaining the patency of parent arteries.It has huge advantage in the treatment of wide-necked,huge,dissecting and pseudo aneurysms without important adjacent branch vessels.This article reviews the application situation and the prospects of development of covered stents in the treatment of intracranial aneurysms.

Objective To explore the potential risk of category Ⅱ fetal heart rate(FHR) tracing according to the latest electron-ic fetal monitoring tracings .Methods The prenatal fetal heart rate tracings in 400 parturients with hospitalized delivery in this hos-pital from November 2011 to October 2012 were classified by category .Among them ,the pregnancy outcomes were compared be-tween the category Ⅰ FHR tracings(control group) and category Ⅱ FHR tracings(observation group) .Results The case number of meconium-staining amniotic fluid ,cesarean rate ,hypamniony and umbilical cord abnormality was significantly higher than that of the control group with statistical difference between the two groups (P<0 .05);the case number of neonatal asphyxia ,aging of pla-centa and neonatal death had no statistical difference between the two groups (P>0 .05);among the groups with various fetal heart monitoring abnormalities ,the rate of meconium-staining amniotic fluid in the decreased variation group was significantly higher than that in the fetal tachycardia group ,the difference showing statistical significance (P<0 .05);the rate of meconium-staining amniotic fluid in the fetal tachycardia group was significantly higher than that in the prolonged acceleration and ineffective acceleration group with statistical difference (P< 0 .05);the pregnant outcomes had no statistical differences among the other groups .Conclusion Compared with the category Ⅰ FHR tracings ,the category Ⅱ FHR tracings indicate a potential risk to the fetus ,which need to strengthen the prenatal and intrapartum fetal monitoring .

Objective To observe the therapeutic effect of red peony root decoction (RPRD) on model rats with acute pancreatitis (AP),and the effect on the expression of NF-κB,TNF-α and IL-6.Methods Forty SD rats were randomly divided into five groups:normal control group (group A),AP model groups (group B,24 h; group C,72 h) and RPRD treatment groups (group D,24 h; group E,72 h).There were 8 rats in each group.The AP models were induced by intraperitoneally injecting with L-arginine.After the model was established,rats of group B and group C were treated with intra-gastric instillation of NS,and rats in group D and group E with RPRD.At 24 and 72 hours after induction of AP,rats in each group were sacrificed and blood samples were taken for the measurement of serum amylase,TNF-α and IL-6.The expression of NF-κB p65 protein in the pancreas were detected by Western Blot,and pathological status of the pancreas were analyzed.Results The serum amylase level in group B and group D was significantly higher than that in group A (P＜0.05),and the level in group D was obviously lower than that in group B (P＜0.05).The serum amylase level in group C and group E was decreased,and there was no difference between group A (P＞0.05).The pathological severity and pathological scores of the pancreas in group D and group E were more lighter than those in group B and group C (P＜0.05).The level of serum TNF-α and IL-6 was significantly decreased in RPRD treatment groups (P＜0.05),group D compared with group B,[ (12.54±2.12)pg/ml,(552.88±81.27)pg/ml] vs.[ (20.53±4.16)pg/ml,(1255.75± 118.82)pg/ml]; group E compared with group C,[ (11.01 ±2.02)pg/ml,(582.87± 88.86) pg/ml] vs [ (23.85 ± 5.59) pg/ml,(1366.33 ± 163.16) pg/ml].The expression levels of NF-κBp65 protein in the pancreas of group D and group E were significantly lighter than those in group C at both time points (group D compared with group B,(0.07±0.055) vs (0.71 ±0.029),P＜0.05; group E compared with group C,(0.15±0.038) vs (0.65±0.026).Conclusion RPRD may alleviate the pathologic changes in AP