Objective To evaluate the efficiency of nursing human resources in the nursing unit of a severe medical department in a hospital by data envelopment Analysis (DEA), to explore the reasons of inefficiency and to provide basis for improving nursing efficiency. Methods Three nursing input indicators from January 2017 to December in a certain ICU (the actual number of beds in the month department, the number of nurses in the department, the actual number of working hours in the department), and 2 indicators of output indicators (total number of hospitalized patients in this month, total number of patients admitted this month) related data were selected. Using DEA to analyze and study. Results From January 2017 to December, the overall efficiency was 0.959, and there were 3 units (accounting for 25％) in overall efficiency =1, pure technical efficiency was 0.984, 6 units of pure technical efficiency =1 (accounting for 50％), and scale efficiency was 0.974, there are 3 units of scale efficiency =1 (accounting for 25％). Conclusion There is significant difference in the level of serious nursing efficiency in our hospital, and the efficiency can be maximized through rational allocation of nursing human resources.

OBJECTIVETo explore the effects of Herba Scutellariae Barbatae flavonoids (HF) in delaying aging of Caenorhabditis elegans and human umbilical vein endothelial cells (HUVECs) in vitro.

METHODSThe effects of 30 or 50 mg/L of HF on nematode life span, reproductive capacity, oxidative stress, and antioxidant enzyme activity of C. elegans were assessed, and the effects of HF on the expressions of the genes encoding antioxidant enzymes and the aging-related genes were analyzed using real-time RT-PCR in both C. elegans and cultured HUVECs. Results Compared with the blank control group, C. elegans with HF treatment showed significantly improved mean and maximum lifespan with a prolonged mean lifespan under acute heat stress at 35 degrees celsius;. HF treatment did not impair the reproductive capacity or cause significant changes in the offspring number of C. elegans. In addition, HF enhanced SOD and CAT activity and up-regulated the expression of daf-16 and sir-2.1 (SIRT1) genes in C. elegans and HUVECs.

CONCLUSIONSHF may delay aging of C. elegans and enhance their resistance to acute heat stress without damaging their reproductive capacity possibly by up-regulating the activity of antioxidant enzymes and expressions of antioxidant genes. HF also may protect endothelial cells against oxidative damage.