Cardiology ; Integrative Medicine ; Medicine, Chinese Traditional

Objective To investigate the therapeutic effect of traditional Chinese medicine,Songling Xuemaikang Capsule on the individual with cerebral infarction reconvalescent and its mechanism.Methods Patients in control group( n =54) received regularly therapy and treatment group( n =55) was treated with regularly therapy and Songling Xuemaikang Capsule for eight weeks respectively.The clinical therapeutic effeets,Barthel index,hemorheology indexes,serum lipid and C-reactive protein (CRP) were determined.Results The total clinical effective rate in treatment group and control group was 70.9％ and 55.6％ (P ＜ 0.01 ).After eight weeks treatment,the scores of Barthel Index,hemorheology indexes,the amounts of serum lipid and CRP in treatment group were improved significantly as compared to the control group ( P ＜ 0.05 or P ＜ 0.01 ).There was no severely side effect found in this trial.Conclusion Songling Xuemaikang Capsule could partly improve patients clinical outcome and life quality.The clinical efficacy of Songling Xuemaikang Capsule on the individual with cerebral infarction reconvalescent should be related to its functioning to promote the recovery of patients' blood hemorheology,and regulate serum lipid and decrease CRP level.

The relationship between carotid artery stenosis and cognitive function are receiving increasing attention.Most studies have shown that carotid artery stenosis has a direct impact on cognitive impairment.Carotid endarterectomy or stenting can improve the cognitive function to varying degrees in patients with carotid artery stenosis.The mechanism of cognitive impairment in patients with carotid artery disease may be associated with hypoperfusion,white matter lesions,multiple lacunar infarction and spontaneous emboli.

Objective To explore the application value of CA125 detection in the diagnosis and treatment of ovarian endometriosis cyst,to provide a reference for clinical diagnosis and treatment.Methods 51 patients with ovarian endometriosis cyst were selected as the observation group,and 51 patients with non endometriosis of benign ovarian cyst were selected as control group.The serum CA125 level was detected and compared between the two growps.Results Before operation,the serum CA125 level of the observation group was (95.29 ± 55.47) U/ml,which was significantly higher than that of the control group (17.96 ± 6.82) U/ml (P ＜ 0.05).In the observation group,serum CA125 level of patients with endometriosis clinical pathological stage Ⅱ-Ⅳ was significantly higher than that of patients with stage Ⅰ (P ＜ 0.05).The endometriosis clinical TNM stage was positively correlated with preoperative serum CA125 level in the observation group (r =0.8795,P ＜ 0.05).The preoperative serum CA125 level in patients with dysmenorrhea score 1 point,2 points,3 points was significantly higher than that in patients with dysmenorrhea score 0 point (P ＜ 0.05).The preoperative serum level of CA125 was positively correlated with dysmenorrhea score in the observation group (r =0.5594,P ＜ 0.05).Conclusion The detection of serum carbohydrate antigen CA125 level has important value in diagnosis,treatment and prognosis of ovarian endometriosis.

Vitamin D deficiency has shown a close relationship with diabetes mellitus.The adequate supplementation of vitamin D can reduce the incidence of diabetes mellitus and improve glucose control by inhibiting inflammatory and immune response,reducing insulin resistance,and promoting insulin synthesis and secretion.

Elevated blood pressure in acute cerebral hemorrhage is very common and is associated with the poor clinical outcomes.Due to the acute elevated blood pressure has impact on hematoma volume,cerebral perfusion pressure and perihematomal edema,etc.,whether aggressively control blood pressure in acute phase still remains controversial.This article reviews the theoretical basis of acute blood pressure management,the relevant clinical trials,and the current problems in spontaneous intracerebral hemorrhage.

Objective To summarize and discuss the clinical results of lumbar catheter drainage auxiliary ventricle drainage surgical puncture on patients with intraventricular hemorrhage about postoperative ADL.Methods The 86 patients with intraventricular hemorrhage admitted to our hospital were randomly divided into two groups,43 patients in control group were given conventional lateral ventricle puncture and continued external drainage,43 patients in observation group were given lumbar catheter drainage auxiliary ventricle drainage surgical puncture based on the conventional treatment.Clinical efficacy were observed,and functional outcomes were evaluated.Results The clearance rate of intraventricular hemorrhage and hospitalized days of the observation group were lower than those of the control group (t =4.23,11.82,all P ＜ 0.05),Quality of life in the observation group was better than that in the control group(x2 =1.73,P ＜ 0.05).Conclusion The clinical result of lumbar catheter drainage auxiliary ventricle drainage surgery for intraventricular hemorrhage in patients is satisfactory and worthy of clinical application.

There are still two outstanding problems in comprehensive quality assessment index system of clinical medical undergraduates:contents of assessment is incomprehensive and every index has no quantitative research based weight.This article elaborated on a complete index framework,covering required knowledge,abilities,attitude,morality of clinical medical undergraduates and proposed a set of methods and processes,including literature research method,system analysis method,brainstorming,expert interviews,Delphi method,and some statistical methods,providing a theoretical basis for the development of comprehensive quality assessment index system for clinical medical undergraduates.

Objective To establish a HPLC method for the determination of baicalin and berberine hydrochloride in Com-pound Qinbo Granules. Methods The gradient elution was performed on a Diamonsil C18 column using method-water (0. 05 % phosphate acid and 0. 1% trithylamine) as mobile phase, and the detection wavelength was 276 nm. Results The linear calibration curve of baicalin was obtained in the range of 10. 08～201.6 mg·L-1 with an average recovery of 98. 1% (RSD=1.11%). The linear calibration curve of berberine hydrochloride was in the range of 4. 08～81.6 mg·L-1 with an average re-covery of 97.9 % (RSD=1.24 %). Conclusion The method is simple and reproducible. It can be used for the quality con-trol of Compound Qinbo Granules.

Objective To explore the differential diagnosis value of DWI ADC for breast lumps,improve the diagnosis of breast cancer specificity.Methods 93 patients with 105 breast tumors were performed with routine MR series and DWI,and the ADC values were measured.Results Lesions ADC values:average ADC value 43 benign lesions in 37 cases was(1.37±0.36)×10-3 mm2/s,the different value between max and min was(0.63±0.19)×10 -3s/mm2.Average ADC value of 62 malignant lesions in 58 patients was(0.90±0.53) × 10 -3 mm2/s,the different value between max and min was(0.91±0.27)×10-3 mm2/s.By statistical analysis,both average ADC values and the max and the min ADC difference value were very significantly different(P＜0.01).Draw diagnosis benign and malignant lesions ROC curves,with ADC values 0.11×10 -3 mm2/s for critical value to judge benign and malignant standard,sensitivity was 67％,specificity was 72％.With 1.0×10- 3 mm2/s for critical value,specificity can raise to 84％,and sensitivity came to 60％.With the maximum and minimum ADC difference value 0.75 × 10-3s/mm2 for critical value,sensitivity was 67％,specificity was 68％.If with 0.80 for critical value,sensitivity was 53％ and specificity 82％.Conclusion The average ADC values of DWI were significant for the identification of benign and malignant lesions.