The current graduate student curriculum of medical colleges and universities has not been able to satisfy the actual need of cultivating the medical graduate students. In certain extent it stresses the natural sciences, theory curriculum and knowledge instruction more than humanities social sciences,technical curriculum, and cultivation of students' ability. Based on the reform of our curriculum setup, the author put forward some suggestions such as expanding the course resources, enriching the content,implementing the second-level management system, being clear about the different cultivation flow and the curriculum name; paying attention to staff construction and perfecting graduate student curriculum assessment and so on.

Discussions were made regarding the burden of persuasion and that of proof in tort lawsuits,distribution of the burden of persuasion in both medical tort cases and those in non-medical malpractice tort lawsuits.It is found that in cases involving tort of medical institutions,medical behavior tort and non-medical tort cases should be set apart depending on the nature of the lawsuit.Under the existing legal system,it is also necessary to distinguish the medical behavior tort incurred by medical malpractice from that irrelevant to malpractice.which will be critical for distribution of the burden proof and calculation of the compensation.

China ; Drugs, Chinese Herbal ; standards ; Ethics, Medical ; Humans ; Medicine, Chinese Traditional

From the three aspects of university,family and the students themselves,the article points out that universities should transform the teaching thought and approaches and give the students poor in study the teaching guidance and humane care,parents should grasp the laxation of educating their children and students should pay attention to regulation and self-regulation.Only through the joint efforts,can the students walk out of study confusion to realize the healthy development

BACKGROUND:To delay the onset of Alzheimer’s disease, transplantation of viable and wel-differentiated stem cel s is expected to repair neural tissue, which has been an issue of concern. OBJECTIVE:To explore the effects of different doses of human umbilical cord mesenchymal stem cel s (hUCMSCs) on learning and memory ability of Alzheimer’s disease rats. METHODS:Fifty Sprague-Dawley rats, 7 months of age, were randomized into normal, model, high-, middle-and low-dose hUCMSCs groups (n=10 per group). Rats in model and UCMSCs groups were used to make Alzheimer’s disease animals through intraperitoneal injection of 150 mg/kg D-galactose for 90 days, and rats in the normal group were given intraperitoneal injection of normal saline for 90 days. In the three hUCMSCs group, passage 3 hUCMSCs at doses of 1×105/0.2 mL/20 g, 5×105/0.2 mL/20 g, and 1×106/0.2 mL/20 g were injected via the tail vein, respectively. Forty-five days after cel transplantation, Morris water maze test was used to detect rat’s learning and memory abilities, and hematoxylin-eosin staining was used to observe pathological changes of the rat hippocampal CA1 region. RESULTS AND CONCLUSION:Compared with the normal group, the rats in the model group showed significant reduction in the ability of learning and memory. Compared with the model group, the escape latency was significantly shortened in the middle-dose hUCMSCs group (P<0.05), while the number of passing times through the platform was increased significantly (P<0.05). In the model group, the cel s in the hippocampal CA1 region were arranged irregularly with unclear nucleoli and a part of cel s were concentrated and deeply stained. In the middle-dose hUCMSCs group, the cel s in the hippocampal CA1 region were arranged regularly with clear nucleoli, and only individual cel s were stained deeply. These findings indicate that middle-dose hUCMSCs transplantation can improve the learning and memory abilities of Alzheimer’s rats.

Child, Preschool ; Foreign Bodies ; surgery ; Humans ; Intestines ; Laparoscopy ; methods

OBJECTIVETo observe the effects of different ignition locations of moxa stick on temperature of needle body and surrounding environment during warm needling, so as to provide experimental references for clinical manipulation.

METHODSA high-accuracy infrared temperature measuring instrument was applied during warm needling to measure the temperature of needle body and surrounding environment at different ignition locations. The ignition method was divided into 2 ignition types with 4 measuring locations. The first method was to ignite moxa stick from upper-end to measure the temperature of needle body and surrounding environment 2 cm and 3 cm away from bottom-end of moxa stick; the second one was to ignite moxa stick from bottom-end to measure the temperature of needle body and surrounding environment 2 cm and 3 cm away bottom-end of moxa stick. Each ignition method was repeatedly measured for 5 times. The averaging values of measurement results which were processed with superposition method at identical time point were used to draw a temperature curve.

RESULTSWith any identical ignition method, the maintenance time of moxibustion temperature 2 cm away from bottom-end of moxa stick was longer by 3 min compared with that from 3 cm, for bottom-end ignition and upper-end ignition, in the case of 30 degrees C to 35 degrees, more ignition time could be kept from bottom-end ignition; in the case of more than 35 degrees C, the maximum temperature of needle body by upper-end ignition was higher by 5 degrees C than that by bottom-end ignition. The bottom-end ignition could achieve earlier effective initial time of moxibustion temperature. From the curves, bottom-end ignition was characterized by left-shift peak while upper-end ignition was characterized by right-shift peak.

CONCLUSIONThe ignition location of warming needling seems to be reasonable if moxa stick is ignited from bottom end which is 2 to 3 cm away from skin.

Occupational Health

Adult ; Asbestos ; adverse effects ; Humans ; Male ; Mesothelioma ; chemically induced ; Occupational Diseases ; chemically induced ; Pleural Neoplasms ; chemically induced

OBJECTIVE: Post-traumatic healing style is an important link in the process of wound healing. Scarless healing of fetus skin after trauma is the ideal healing style that is hunted for by people. The results of studies on the mechanism of scarless healing were reviewed to explore the mechanism of scarless healing of fetus skin.DATA SOURCES: Computer was applied to retrieve Medline database on the articles relating to the mechanism of scarless healing of fetus skin from January 1970 to December 2003. Docuterms were "fetus, skin and scarless healing". Language in the articles was limited to English.STUDY SELECTION: The documents were examined at first to exclude the study on non-healing mechanism. Full texts were found in the surplus documents. The inclusive criterion was the foundational experiment on the mechanism of scarless healing. Clinical trial and phenomenal study on scarless healing were excluded.DATA EXTRACTION: Forty-eight articles on experimental study relating to embryonic scarless healing were collected in all. Sixteen experiments accorded with the inclusive criterion and 32 were excluded.DATA SYNTHESIS: Sixteen experiments discussed the relationship between the fetus and scarless healing on terms of growth environment, inflammation reaction to trauma and regulation of fibroblast in organism, extracellular matrix and nany cellular factors.CONCLUSION: Growth environment of fetus has not so much relationship with the mechanism of scarless healing after trauma. Low reaction of fetus to inflammation, different extracellular matrix, component of collagen fiber and cell factors may take part in scarless healing process. Regulation of gene expression may play an important role in the process. But the concrete mechanism of scarless healing is not clear yet and still needs more researches and elucidations.