Objective To explore the quality of life (QoL) among the female condyloma acuminatum patients.Methods 118 female condyloma acuminatum patients were interviewed face-to-face by the well-trained nurses with questionnaire including SF-36 Chinese version,the t-test and x2 test were used to compare the scale scores of SF36 between the patient and control groups.Results There were 101 eligible questionnaire,the scale scores of physical function(PF) and bodily pain(BP) were highest in the patient group,the scale score was (92.9 ± 10.5)points and (75.0 ± 1 1.2) points,respectively.Role limitations due to emotional problems (RE) was the lowest with the scale score only(50.8 ± 13.7)points.All scale scores of SF-36 in patient group,except PF(no statistical significant),were lower than that in the control group (all P ＜ 0.01).Conclusion In the female condyloma acuminatum patients,the QoL is lower significantly than that in the control group,especially in emotional scales.

Diagnosis, Differential ; Humans ; Medicine, Chinese Traditional

Carotid Stenosis ; surgery ; Endarterectomy, Carotid ; Humans

Peanuts, corn and other food products are prone to aflatoxins (AF). AF was listed as a human carcinogen by the International Agency for Research on Cancer (IARC), especially aflatoxin B1 (AFB1), as it is considered the most prevalent and toxic. China is a big peanut producer, so carrying out pollution investigation and risk assessment in peanuts and their products is crucial to formulate prevention measures, protect export trade and maintain health. This paper summarizes the AF pollution of peanuts and their products in the Huang-Huai-Hai Basin, Yangtze River Basin, Southeast Coast and Northeast region of China from 2015 to 2021, and the application of dietary AF exposure risk assessment methods, providing a basis for strengthening the supervision of AF pollution in peanuts and their products, and ensuring food safety.

Paralytic shellfish poisoning contamination is a threat to human health. Based on review of research articles pertaining to paralytic shellfish poisoning contamination in shellfishes and assessment of dietary exposure to paralytic shellfish poisoning in coastal cities of China from 2007 to 2022, the article describes the status of paralytic shellfish poisoning contamination, influencing factors and dietary exposure assessment in different sea areas of China (Bohai Sea, Huanghai Sea, East China Sea and South China Sea), and the relatively high-level contamination of paralytic shellfish poisoning in shellfishes is found to strongly correlate with red tides caused by season and water temperature in the Bohai Sea and South China Sea areas. Acute exposure assessment based on point estimate model is commonly used for assessment of dietary exposure to paralytic shellfish poisoning, and the risk of human dietary exposure to paralytic shellfish poisoning is within the acceptable range in most areas. Intensified monitoring of paralytic shellfish poisoning contamination in shellfishes and full consideration of parameters like processing factor during dietary exposure assessment are required in the future to allow more precise results.

Abstract Zearalenone (ZEN), a nonsteroidal mycotoxin produced by fusarium with estrogen-like effects, and it contaminates various types of cereals and their products to varying degrees. Wheat and rice are the staple foods of Chinese residents, and understanding the contamination status and dietary exposure risk of ZEN in grains and their products is of great significance for maintaining food safety and promoting population health. This article reviewed the publications between 2012 and 2023 on ZEN contamination and dietary exposure assessment in cereals and their products, and found that the dietary exposure risk of ZEN contamination in cereals and their products was low. Continued efforts are needed to strengthen food safety monitoring and regulatory oversight to ensure food safety.

Acute Disease ; Adolescent ; Adult ; Aluminum Compounds ; poisoning ; Child ; Female ; Humans ; Male ; Middle Aged ; Pesticides ; poisoning ; Phosphines ; poisoning ; Poisoning ; diagnosis ; therapy

History, 20th Century ; History, 21st Century ; Humans ; Minimally Invasive Surgical Procedures ; history ; trends ; Neurosurgery ; history ; trends

Objective To observe the relationship between homocysteine (Hcy),C-reactive protein (CRP) and type 2 diabetes peripheral vascular disease (PVD).Methods Fifty-eight patients with type 2 diabetes according to the condition of PVD were divided into simple type 2 diabetes mellitus group (DM group,30 cases) and PVD group (28 cases).Twenty-five healthy people were chosen at the same period as control group.The fasting blood glucose (FBG),glycosylated hemoglobin (HbA1c),total cholesterol(TC),triglyceride (TG),high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C),Hcy and CRP levels were detected among 3 groups,and the body mass index (BMI),ankle brachial index(ABI) was calculated.Results The BMI,TG,TC and HDL-C levels among 3 groups had no statistical significance (P ＞0.05).The FBG,HbA1c and LDL-C in DM group and PVD group were significantly higher than those in control group [(7.54 ± 1.25),(8.12 ± 1.57) mmol/L vs.(4.68 ±0.54)mmol/L; (6.92 ± 0.89)％,(7.54 ± 0.97)％ vs.(4.80 ± 0.54)％ ; (3.79 ± 0.73),(4.41 ± 0.93) mmol/L vs.(2.68 ± 0.54) mmol/L],and the difference was statistically significant (P ＜ 0.05).But the difference between PVD group and DM group had no statistical significance (P ＞ 0.05).Hcy and CRP in DM group and PVD group were higher than those in control group [(10.26 ± 3.62),(19.83 ± 5.54) μ mol/L vs.(8.92 ± 2.41)μ mol/L; (4.12 ±0.57),(5.47 ±0.85) mg/L vs.(2.73 ±0.54) mg/L],ABI was lower than that in control group(0.92 ± 0.18,0.81 ± 0.16 vs.1.02 ± 0.23),and the difference was statistically significant (P ＜ 0.05);Hcy,CRP in PVD group were obviously higher than those in DM group,ABI was lower than that in DM group,and the differences were statistically significant (P＜ 0.05).Spearman analysis showed that Hcy was negatively correlated with ABI (r =-0.635,P ＜ 0.05),CRP was negatively correlated with ABI (r =-0.529,P ＜ 0.05),and Hcy was positively correlated with CRP (r =0.528,P ＜ 0.05).The partial correlation analysis results showed that Hcy and ABI still showed a negative correlation (r =-0.315,P ＜ 0.05),CRP and ABI still showed a negative correlation (r =-0.243,P ＜ 0.05).Conclusion Hcy and CRP participating in the occurrence and development of type 2 diabetes PVD,can be used as a predictor of type 2 diabetes PVD.

Objective To investigate the diagnostic value of CT virtual endoscopy on the small intestine (CTVE)technology for intestinal diseases. Methods Forty-nine cases with suspected small bowel disease were tested by CTVE from December 2010 to February 2014. They also were performed. Results Of 49 patients, operation or electronic endoscopy showed that 9 cases were benign tumors,29 cases with malignant tumors,3 cases with intestinal polyps,4 cases with intestinal inflammation,2 cases with bowel dysfunction and 2 cases with normal intestinal. CTVE test showed that 11 cases were with benign tumors,29 cases with malignant tumors,2 cases with intestinal inflammation,1 case with intestinal polyps,4 cases with intestinal dysfunction and 2 cases with normal small intestine. Better consistency between the two diagnosis was seen(Kappa = 0. 70). The accurate rate of diagnosis was 85. 71%(42 / 49). The correct rate of CTVE diagnosis of space occupying lesions was 90. 24%(37 / 41). The correct rate of non occupied lesions was 50. 00%(3 / 6). Conclusion CTVE technology has the advantages of simple operation,safe,painless,and clinical diagnosis of small bowel disease rate is higher especially for small bowel accounted disease. It is worthy of clinical application.