1.ANALYSIS OF PATIENTS WITH POTENTIALLY INAPPROPRIATE MEDICATION IN HOSPI-TALIZED ELDERLY SURVEY
Modern Hospital 2015;(4):115-116,120
Objective To retrospect survey of elderly patients potentially inappropriate medication among in -patients.Methods With Beers standard of judgment (2012 Edition) as the basis of our hospital, 320 patients over 65 years old hospitalized patients with potential risk of drug evaluation were to determine the prevalence of potentially inappropriate medication.Results 320 cases of elderly hospitalized patients with an average age of 73.4 years old, the average drug 8, 43 cases (13.6%) of potential drug -related inappropriate medication, 28 cases (8.7%) of po-tential associated with the disease or condition is not appropriate medication .Conclusion Elderly hospitalized pa-tients potentially inappropriate medication is serious , and we should take various measures to prevent the irrational drug use.
2.Therapeutic efficacy of peripheral T cell lymphoma patients treated with first-line intensive chemotherapy followed by autolo-gous stem cell transplantation
Yuan YAO ; Pingyong YI ; Xiyu LIU ; Fang ZHOU ; Zhongyi SUN ; Zhou OUYANG ; Junqiao HE ; Lijun HUANG
Journal of Chinese Physician 2014;(2):227-230
Objective To investigate the outcomes of unselected peripheral T cell lymphoma (PTCL) patients treated with in-tensive first-line chemotherapy with high-dose therapy followed by autologous stem cell transplantation (ASCT).Methods Here a nonrandom study was reported for 23 PTCL patients treated with first-line intensive chemotherapy followed by autologous stem cell trans-plantation and 23 PTCL patients treated with conventional chemotherapy during January in 2000 to 2011 .All patients had received E-CHOP for 6~8 cycles, and autologous stem cell transplantation group was administrated with intensive chemotherapy followed by ASCT after complete remission or partial remission .Results There was no statistically significant difference in short-term therapeutic effect between two groups( P >0.05), but the 5-year overall survival(OS) of autologous stem cell transplantation group( 58%) was higher than conventional chemotherapy group , as well as 5-year disease-free survival time (DFS) (45%in autologous stem cell transplanta-tion group, and 21%in conventional chemotherapy group ) with both statistical significance ( P <0.05).Only the incidence of Ⅳ° myelosuppression in autologous stem cell transplantation group ( 100%) was higher than that in conventional chemotherapy group ( 13%) ( P <0.01 ) .Conclusions First-line intensive chemotherapy followed by autologous stem cell transplantation for peripheral T cell lymphoma was quietly safe utility , it was better than conventional chemotherapy which would be considered as first -line method.