Objective To explore the effect of nursing risk management basing on concept of circulation quality control in decreasing poor incision healing after cesarean section.Methods Two-hundred puerperae who received cesarean section from September 2014 to August 2016, and whose clinical data were analyzed retrospectively, were divided into risk management group and conventional group according to nursing measures, each with 100 cases. Conventional nursing intervention was conducted to puerperae in the conventional group, while besides that, puerperae in the risk management group were taken care of under the nursing risk management basing on the concept of circulation quality control. Anxiety status of puerperae in the two groups were evaluated, with the self-rating anxiety scale (SAS) , at admission to the hospital, 1 day after intervention, 3 days after intervention and 1 day before leaving hospital. Satisfaction towards nursing was evaluated by a self-designed scale of patients' satisfaction towards nursing in department of gynecology and obstetrics. Incidence of poor incision healing of all puerperae were statistically analyzed.Results Total incidence rate of poor incision healing in the risk management group was 5.00%, lower than 13.00% in the conventional group (χ2=3.91, P<0.05); SAS scores of puerperae in the risk management group at 1 day, 3 days after intervention, and 1 day before leaving hospital were significantly lower than that in the conventional group (P<0.05); satisfaction towards nursing in the risk management groups was significantly higher than that in the conventional group (P<0.05).Conclusions Conducting nursing risk management basing on concept of circulation quality control to puerperae after cesarean section can effectively reduce incidence rate of poor incision healing, relieve the patients' bad emotions, and improve their satisfaction towards the nursing care.

Objective To study the best formulation and technology of quercetin-loaded polylactic-co-glycolic acid-D-α-tocopheryl polyethylene glycol 1000 succinate(PLGA-TPGS) nanoparticles(QPTN) with QT as model drug and PLGA-TPGS as polymer materials by orthogonal tests,and to investigate the in vitro stability of QPTN. Methods To ensure the best formula-tion and technology for preparing QPTN,single-factor test was established to determine the influence of the ratio of quercetin to PLGA-TPGS,the concentration of TPGS as emulsifiers,the ultrasonic power and ultrasonic time to the particle size,drug loading (DL) and entrapment efficiency(EE).According to single-factor test,the factor levels of nanoparticles were set to select the best prescription and technology of QPTN by orthogonal test.The stability of QPTN was examined using the effecting factor test,accel-eration test and long-term test. Results The best formulation and technology of QPTN was that the ratio of quercetin to PLGA-TPGS was 3:10 (W:W) with 0.05% TPGS as emulsifier,the mixed solution was sonicated for 6 min at 200 W.The average particle size,DL and EE of QPTN prepared under the conditions described above were (155.4 ± 2.7) nm,(21.6 ± 1.5)% and (93.7±2.9)% (n=6),respectively.In the in vitro stability test,QPTN showed a good stability at high temperature,high humidity and strong light condition. Conclusion The best formulation and preparation technology of QPTN was selected.QPTN got small particle size,high DL and EE,and good in vitro stability.