2.Choice and Practice of the new transform moed of science and technology achievemevts of military medicine
Zhongwu LIN ; Yi PENG ; Bin TAN ; Shinan CAO ; Junjie MA ; Fei DU ; Zhongze WANG
Chinese Journal of Medical Science Research Management 2014;27(5):541-543,553
With the development of civil military integration,military scientific research institu tes are facing the challenge of constructing a new mode of translating scientific and technological achievements into practice and enhancing translational efficiency.This paper began with the evolution of translation mode in military institutes and discussed the flaws and insufficiency of current mode,then a triple helix translation mode,which encompass government,industry and research,was introduced and fully explained for future reference.
3.A Study of Resection of Pterygopalatine Fossa Tumor by Transnasal Recessed Approach under Nasal Endoscope
Journal of Medical Research 2018;47(3):130-133
Objective To analyze and discuss the surgical outcome and complications of resection of pterygopalatine fossa tumor along the lateral wall of maxillary sinus.Methods Nine patients with pterygopalatine fossa tumors received from March 2012 to June 2015 were treated by transnasal endoscopic approach to resect the pterygopalatine fossa tumors by transnasal recess-maxillary sinus approach.Surgery used general anesthesia,while controlling intraoperative hypotension in patients.The CT and MRI examinations of the sinuses were performed before operation,and the patients were followed up regularly.Results All of the patients underwent successful operation.The pterygopalatine fossa tumors were cleared once,and were discharged after 6-12 days.Although there were 2 patients with mild facial paralysis of the maxillary nerve in 3-24 months of follow-up,there was no serious complication or recurrence.Conclusion The removal of pterygopalatine fossa tumors by transnasal endoscopic approach can safely and effectively remove the tumor tissue and preserve the integrity of the lateral wall of the nasal cavity,minimize facial trauma and nasal cavity function.It is a complication less,low recurrence rate,rapid recovery of the new minimally invasive approach,it is worth to promote the use of clinical.
4.Laparoscopic assisted small incision biliary tract exploration in treatment of recurrent extrahepatic bile duct stones
Zhongwu MA ; Haibo YU ; Bujian PAN ; Hongliang SONG ; Xiaodan JIN
Chinese Journal of Hepatobiliary Surgery 2018;24(5):309-312
Objective To compare the clinical results between laparoscopic assisted small incision biliary duct exploration with traditional biliary exploration for patients with recurrent extrahepatic bile duct stones who had undergone biliary surgery for ≥2 times.Methods The clinical data of patients with recurrent extrahepatic bile duct stones who had undergone biliary surgery for ≥2 times,and underwent laparoscopic assisted small incision biliary duct exploration or traditional biliary exploration from September 2011 to June 2016 were retrospectively studied.Results 23 patients underwent laparoscopic assisted small incision biliary duct exploration (Group A),and 24 patients underwent traditional biliary exploration (Group B).The time spent on abdominal adhesion separation in group A and group B was (74.7 ± 20.5) min and (90.8 ± 20.3) min (P < 0.05),respectively.The amount of intraoperative blood loss were (67.4 ± 35.6)ml and (107.4±31.5) ml (P <0.05).The number of patients with intestinal injury were 0 and 4.The postoperative time to first pass flatus was (26.9 ± 3.8) h and (35.5 ± 6.5) h (P < 0.05).The durations of postoperative hospital stay were (8.1 ± 1.4) d and (12.8 ± 2.9) d,respectively,(P < 0.05).The numbers of patients who required postoperative analgesics were 10 and 19 cases (P < 0.05).The number of patients with postoperative incisional wound infection were 1 and 6.There was no significant difference in the time spent on biliary exploration,incidences of biliary leakage,pulmonary infection rate,hospitalization cost and liver function status between the two groups of patients (P > 0.05).Conclusions Laparoscopic assisted small incision biliary duct exploration was safe and effective for patients with recurrent extrahepatic bile duct stones who had undergone biliary surgery for ≥2 times.This operation can be used as a preferred procedure.
5.Concurrent percutaneous transhepatic papillary balloon dilatation combined with laparoscopic cholecystectomy for gallstones and common bile duct stones
Zhongwu MA ; Haibo YU ; Bujian PAN ; Feng CHEN ; Hongliang SONG ; Xiaodan JIN
Chinese Journal of General Surgery 2018;33(8):645-648
Objective To evaluate the clinical effectiveness and safety of percutaneous transhepatic papillary balloon dilatation (PTBD) combined with laparoscopic cholecystectomy (LC) for concurrent gallstones and common bile duct stones.Methods From Sep 2010 to Dec 2016,23 patients undergoing PTBD + LC were retrospectively compared with 34 cases recieving laparascopic common bile duct exploration (LCBDE) + LC.Parameters included surgical success rate,postoperative complications,residual stone rate,operation time,postoperative anal exhaust time,postoperative hospital stay,and hospitalization expenses.Results In this study 23 patients received PTBD + LC,34 patients received LCBDE + LC.In PTBD + LC group:the operation success rate was 91.3%,postoperative complications (2 cases of pancreatitis,3 cases of pulmonary infection,1 case of incisional infection),and the postoperative residual stone rate was 4.3%.In LCBDE + LC group:surgery success rate was 88.2%,postoperative complications (bile leakage 2 cases,lung infection 2 cases,incisional infection 1 case),postoperative residual stone found in 2.9%;The success rate,postoperative complications and postoperative residual stone rate between the two groups were not statistically different (P > 0.05),nor in operation time,postoperative anal exhaust time,and hospitalization cost (P > 0.05).PTBD + LC group had shorter hospital stay (P < 0.05).Conclusions PTBD combined with LC is effective and safe procedure for the treatment of gallstones and bile duct stones.
6.Lateral cervical lymph node mapping in papillary thyroid carcinoma: a prospective cohort study
Naisi HUANG ; Ben MA ; Qing GUAN ; Yunjun WANG ; Li ZHOU ; Wenjun WEI ; Zhongwu LU ; Shuwen YANG ; Weibo XU ; Jun XIANG ; Qinghai JI ; Yu WANG
Chinese Journal of Clinical Oncology 2018;45(20):1053-1056
Objective: To explore the value of nanoparticles (CN) in lateral cervical lymph node mapping in papillary thyroid carcinoma using carbon. Methods: Thyroid cancer patients with suspicious lymph node metastasis but without typical signs of metastatic disease from March 2016 to November 2017 in Fudan University Shanghai Cancer Center were prospectively included in the cohort. Neck dissection was performed in all patients (compartmentsⅡ-Ⅴ). Suspicious lateral lymph node metastasis was identified using pre-operative ultrasound or computed tomography. CN were used for lymph node mapping during surgery. Results: A total of 70 surgeries were performed in 67 patients, among which 57 were found to have lateral lymph node metastasis (81.4%). The median number of CN-dyed lateral lymph nodes was 6. Compartment IV had the highest number of CN-dyed positive lymph nodes as well as the highest rate of metastasis, followed by compartmentⅢ. In compartmentsⅢandⅣ, the incidence of lymph node metastasis was significantly higher in the CN-dyed group than in the CN-undyed group (P<0.001). When the final pathology of neck dissection was set as the gold standard, lateral CN-dyed lymph node biopsy was found to have a sensitivity of 86.0%; its negative predictive value was 61.9% and its overall accuracy was 88.6%. Conclusions:Injection of CN during surgery was a potential method of mapping lateral lymph nodes in papillary thyroid carcinoma. CompartmentⅢ-ⅣCN-dyed lymph node biopsy had a satisfactory sensitivity and thus, served as a reasonable range for lymph node biopsy.