Objective Subjective to identify the significance of interstitial implantation of 125Ⅰ seeds in stage Ⅳ pancreatic cancer patients.Methods Retrospectively analysis the clinical datum of 18 cases of stage Ⅳ pancreatic cancer patients treated with the 125Ⅰ seeds implantation, and observe the pain relief rate and the average survival period, then compare with the bulk of domestic statistical datum.Results The rate of easement of pain was 70.6% (12/17) , and the mean time begin to relieve was 2.9 days .The life span after the operation was be-tween 2.5 and 11.5 months , and 5.2 months on average,which is longer conspicuously than the statistics of the past.Conclusions The methods of interstitial implantation of 125Ⅰ seeds can upgrade the quality of the life and living efficiently of stage Ⅳ pancreatic cancer patients.

CT colonography (CTC) has been widely used in diagnosis of colon diseases. Computer-aided detection (CAD) automatically detects the locations of suspicious lesions on CTC, and provides radiologists with a second opinion. CAD has the potential to increase radiologists' diagnostic performance in the detection of lesions and to decrease variability of the diagnostic accuracy among readers. The current fundamental scheme, the key techniques used for detection of lesions on CTC, the detection performance, as well as the pitfalls, challenges, and the future of CAD were reviewed in this article.