1.Application value of adjustable closed loop in SBS with ostomy in continuity
Qi GAO ; Zhaoping LAN ; Weike XIE ; Qi WANG ; Yongkang PAN ; Chaoxiang LU ; Zhongwen LI ; Lei WANG
Chinese Journal of Primary Medicine and Pharmacy 2020;27(17):2107-2111
Objective:To evaluate the effect and safety of adjustable closed loop(ACL) in the treatment of short bowel syndrome (SBS).Methods:From January 2017 to December 2017, the clinical data of 2 cases with ostomy in continuity after surgery in Children's Hospital Affiliated to Xi'an Jiaotong University were analyzed.The age was 1 and 3 months, both were females, and preservation of intestinal tube length were 65 cm and 60 cm respectively.They were all diagnosed SBS with a lot of stool like water.Self-made ACL was installed to maintain SBS.The blood circulation of stoma, weight, BMI, defecating, abdomen, nutrition status changes, nursing convenience, intestinal infection susceptibility were observed.Results:There was no necrosis in stoma, and the overall condition was improved, and no significant increase in abdominal distension.ACL used in babies with ostomy in continuity could improve the anus stool, weight, nursing convenience.Conclusion:ACL installed in baby with SBS could contribute to intestinal management, and is easy to install.
2.Surface modification of multifunctional ferrite magnetic nanoparticles and progress in biomedicine.
Linxue ZHANG ; Nuernisha ALIFU ; Zhongwen LAN ; Zhong YU ; Qifan LI ; Xiaona JIANG ; Chuanjian WU ; Ke SUN
Journal of Biomedical Engineering 2023;40(2):378-383
Magnetic ferrite nanoparticles (MFNPs) have great application potential in biomedical fields such as magnetic resonance imaging, targeted drugs, magnetothermal therapy and gene delivery. MFNPs can migrate under the action of a magnetic field and target specific cells or tissues. However, to apply MFNPs to organisms, further modifications on the surface of MFNPs are required. In this paper, the common modification methods of MFNPs are reviewed, their applications in medical fields such as bioimaging, medical detection, and biotherapy are summarized, and the future application directions of MFNPs are further prospected.
Ferric Compounds
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Magnetic Resonance Imaging/methods*
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Magnetics
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Magnetite Nanoparticles/therapeutic use*
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Nanoparticles