1.Clinical evaluation of the patterns and risk factors of bone cement leakage and its related risk factors secondary to vertebral augmentation
Baoliang ZHANG ; Zhongqiang CHEN
Chinese Journal of Orthopaedics 2021;41(5):330-338
Percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) are safe and effective minimally invasive spinal techniques for the treatment of osteoporotic and pathological vertebral fractures, which are widely used in clinical practice. Cement leakage is the most common complication, which can lead to serious consequences such as adjacent vertebral refracture, pulmonary or cerebral embolism and paraplegia. Clinically, bone cement can penetrate into different sites along different paths, form different morphologies, and present different clinical symptoms. Therefore, an impeccable classification of bone cement leakage is beneficial to study its incidence, risk factors and prevention and treatment measures. So far, domestic and foreign scholars have proposed a variety of bone cement leakage classifications and elucidated its clinical significance despite certain limitations, but no uniform standard is established. Therefore, this review summarizes various classification and risk factors of cement leakage and evaluates their clinical implications, aiming at providing a reference for further clinical studies.
2.Content Determination of Polysaccharide in Pinellia Tuber
Jingfen WU ; Yuanyuan ZHANG ; Zhongqiang JI
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(10):-
Objective To determine the content of polysaccharide of prepared pinellia tuber. Methods The content was determined by sulfuric acid-anthrone colorimetric method with wavelength at (624?1)nm. Results The content of polysaccharide was 2.533 mg/g in prepared pinellia tuber. The average recovery was 99.54% and RSD was 1.69%. Conclusion The methods was simple, steady and reproducible.
3.The clinical characters and surgical managements of congenital laryngeal cysts in infants.
Yamin ZHANG ; Zhinan WANG ; Zhongqiang XU
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(9):631-634
OBJECTIVE:
To classify congenital laryngeal cysts in 62 newborn or infants, and to discuss the characteristics of different operation mode.
METHOD:
The clinical data of 62 infants with laryngeal cysts treated were reviewed retrospectively. After the examination of neck palpation, laryngoscope and imaging (CT or MRI), all patients were under general anesthesia of laryngeal cyst excision. we select operation mode according to the classification. Classification include: 61 cases of cysts were confined to the larynx, 1 case was beyond the larynx. Surgical managements include: an excision through external carotid approach in 1 case beyond the larynx, 61 cases had endoscopic excision under general anesthesia (12 cases with traditional bite exception, 12 cases with powered system and 37 cases with low-temperature radiofrequency ablation).
RESULT:
The operations was successful. No recurrence was found after 0.5 to 7 years follow-up.
CONCLUSION
To chose surgical management after classification and preoperative assessment, which could avoid unnecessary opening surgical approaches, reducing the recurrence, and preventing repeated endoscopic treatment or tracheotomy. The low-temperature radiofrequency ablation had the advantages of short operation time, less bleeding, little injury, low recurrence rate and light postoperative reaction. It is worthy of clinical promotion.
Child, Preschool
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Cysts
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congenital
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surgery
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Female
;
Follow-Up Studies
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Humans
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Infant
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Infant, Newborn
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Laryngeal Diseases
;
congenital
;
surgery
;
Male
;
Retrospective Studies
4.Application of rDNA Sequence Analysis in the Study of Arbuscular Mycorrhizal Fungi
Lingzhi LIU ; Peijun LI ; Zhongqiang GONG ; Yulong ZHANG
Microbiology 1992;0(05):-
Arbuscular mycorrhizal fungi(AMF) are ancient,asexual,and obligate symbiotic endophytes which have not been cultured in vitro.So there is some limitation in the study of mycorrhizology.While the molecular technology based on DNA analysis could increase the detection sensitivity and specificity of AMF.rDNA sequence homology and variability can reveal the relationship between species and their evolution.Thus rDNA sequence analysis are widely used in the classification,identification,genetic,ecology and bio-diversity of AMF.This article summarizes the rDNA sequence analysis techniques and their application in phylogeny,molecular detection and community structure of AMF in different plant vegetation.
5.Study on the application of big cup membranate stent on restenosis after stenting for carcinoma of esophago cardia
Xiuping WANG ; Zhongqiang YAO ; Jian LIU ; Yan ZHANG
Journal of Interventional Radiology 2006;0(07):-
Objective To evaluate the clinical value of self-designed big cup membranate stent on restenosis after stenting for carcinoma of esophago-cardia. Methods 12 cases of restenosis after stenting for carcinoma of esophago-cardia were involved in the study. Self-designed big cup membranate stent made by Nanjing Weichuang Company(the length of the cup was 3.5 cm)was placed into the constricted stent under guidance of fluoroscopy. Clinical effect, restenosis, and complications were observed during followed up. Results All the 12 cases of big cup membranat stent placement went along smoothly without indigitation of the cup of the stent. Follow-up of 1.5-8 months showed that 2 cases developed severe restenosis on the big cup of the stent, resulting in third grade difficult deglutition. Among them, one occurred 1 month after stenting, caused by hyperplasia of large amount of granulation tissue; another occurred 6 months after stenting, caused by growth of tumor tissue. 3 cases developed mild to moderate restenosis, 2.3-7 months(mean: 4.6 months)after stenting, with result of first grade difficult deglutition. The remaining 7 cases(mean5.6 months follow-up) did not have difficulty during deglutition. Conclusions Application of big cup membranate stent on restenosis after stenting for carcinoma of esophago-cardia can effectively prevent the stent from moving downwards and thus lower down the rate of restenosis, and postpone the occurrence of restenosis.
6.Hemodynamic changes under general anesthesia in combination with epidural anesthesia during endotracheal intubation in senile patients
Zhongqiang CAO ; Ljun YANG ; Yinjia ZHANG ; Yue CHEN ; Yinghua XU ; Shaoxiao SUN ; Jin ZHANG ; Haier WANG
Journal of Medical Postgraduates 2003;0(07):-
Objective:To compare hemodynamic changes under general anesthesia with those under general + epidural anesthesia during endotracheal intubation in senile patients.Methods:Forty ASA Ⅰ or Ⅱ senile patients aged 65-75 years were equally randomized into a G(general anesthesia) and a GE(general + epidural anesthesia) group and received intravenous injection of sufentanil 0.2 ?g/kg,midazolam 0.06 mg/kg,vecuronium 0.12 mg/kg and propofol 1.6 mg/kg for general anesthesia induction and endotracheal intubation.SBP,DBP,HR,EDV,SV,EF and CO were recorded at 5 different time points,i.e.,before induction(T0),just before intubation(T1),immediately after intubation(T2),1 minute after intubation(T3),and 5 minutes after intubation(T4) via ultrasoundcardiogram.Results:Significant hemodynamic changes were observed in both groups(P
7.Effects of Individual Prehabilitation on Functional Outcome Six Weeks after Total Knee Arthroplasty
Yanyan YANG ; Tongxuan WU ; Qiaoyun ZHANG ; Mouwang ZHOU ; Zijian LI ; Ke ZHANG ; Zhongqiang CHEN
Chinese Journal of Rehabilitation Theory and Practice 2016;22(6):701-708
Objective To observe the effects of individual prehabilitation on the functional outcome six weeks after total knee arthroplas-ty (TKA). Methods The patients undergoing TKA from March, 2013 to August, 2015 were randomly divided into prehabilitation group (n=30) and control group (n=29). The prehabilitation group received individual rehabilitation since enrolled in the study. The control group re-ceived no prehabilitation. All the patients received regular pre-surgical education, surgery and post-surgical rehabilitation. Both groups were evaluated with Numerical Rating Scale (NRS) of pain, active range of motion (AROM), Manual Muscle Test (MMT), fall index, TimedUp and Go(TUG), and Hospital for Special Surgery-Knee Scale (HSS-KS). Results The scores of NRS reduced six weeks after TKA (t>2.342, P<0.05) in both groups, and was lower in the prehabilitation group than in the control group before and six weeks after TKA (t>2.827, P<0.01). There was no significant difference in AROM of knee flexion when enrolling and before TKA in both groups (t<0.648, P>0.05), and it increased in the control group six weeks after TKA (t>3.555, P<0.01), and no increasement was found in the prehabilitation group (t<1.608, P>0.05);the AROM of knee extension increased before TKA in the control group (Z=-2.257, P=0.024), and no increasement was found in the prehabilitation group (Z=0, P=1.000), and it decreased six weeks after TKA in both groups (Z>2.247, P<0.05). The muscle strength of trunk extention and flexion enhanced before TKA in the prehabilitation group (t>2.387, P<0.05), and no change was found in the control group (t<0.940, P>0.05). The muscle strength of trunk extensor and the upside of rectus abdominis showed no statistical difference between two groups six weeks after TKA (t<1.656, P>0.05), the muscle strength of the downside of rectus abdominis and external oblique was more in the prehabilitation group than in the control group (t=2.585, P=0.013). There was no significant difference in the fall index be-fore TKA (t<0.350, P>0.05), and it was lower in the prehabilitation group than in the control group six weeks after TKA (t=-2.837, P=0.007). The time of TUG shortened before TKA in the prehabilitation group (t=3.554, P=0.002), and it prolonged in the control group (t=-4.507, P<0.001), there was no significant difference in it between two groups six weeks after TKA (t=-0.497, P=0.622). The score of HSS-KS increased before TKA (t=-2.621, P=0.015) in the prehabilitation group, and no increasement was found in the control group (t=2.073, P=0.053), and they were higher in the prehabilitation group than in the control group before and six weeks after TKA (t>2.092, P<0.05). Conclusion Individual prehabilitation could reduce pain, and improve the trunk muscles, the ability of walking and the function of the knee before and six weeks after TKA.
8.Efficacy and safety of autologous peripheral blood stem cell transplantation in patients with decompensated hepatitis B cirrhosis
Xingfen ZHANG ; Qinzhi DENG ; Wenhong ZHOU ; Qinghua LIAO ; Zhongqiang PANG ; Jianrong HUANG
Chinese Journal of Clinical Infectious Diseases 2017;10(2):119-124
Objective To evaluate the efficacy and safety of autologous peripheral blood stem cell transplantation (APBSCT) in treatment of patients with decompensated hepatitis B cirrhosis.Methods Sixty two patients with decompensated hepatitis B cirrhosis admitted in Ningbo Second Hospital during January 2010 and December 2013 were enrolled in the study.Patients were randomly assigned in two groups: 50 patients in control group received comprehensive medical treatment only, and 12 patients in combination group received APBSCT on the basis of medical treatment.The levels of serum total bilirubin (TBil), albumin (Alb), alanine aminotransferase (ALT) and prothrombin time (PT) in two groups were mearsured at the 4th,12th,24th week.Overall survival (OS),progression-free survival (PFS) and complications were compared between two groups after 3 years follow-up.SPSS17.0 software was used to analyze the data.Results After APBSCT treatment, the level of Alb and PT at week 4,12 and 24 in combination group improved significantly(tAlb=-4.437,-5.210 and-6.915,tPT=12.083,11.251 and 10.640,all P<0.01),there were also significant differences between combination group and control group (tAlb=4.985, 5.565 and 6.260,tPT =-3.013、-3.727 and-3.983,all P<0.01).The 3-year OS and 3-year PFS of patients in combination group were higher than those of control group [(90.9±8.7)%vs.(60.7±7.4)%, (75.8±12.5)% vs.(47.9±7.3)%](χ2=6.887 and 5.565,P<0.05).Besides,APBSCT had more advantages than control group in reducing ascitic fluid and hepatic encephalopathy(χ2=7.992 and 4.681,P<0.05 or <0.01).Conclusion APBSCT combined with medical treatment can improve liver function and 3-year survival rate with mild adverse reaction in patients with decompensated hepatitis B cirrhosis.
9.Effects of Various Processings on Quality of Angelica dahurica
Qiusheng TAN ; Wenwei ZHANG ; Ling LI ; Caifu DENG ; Shun LUO ; Chuan LUO ; Zhongqiang WEI ; Meiquan YANG
Chinese Journal of Information on Traditional Chinese Medicine 2013;(7):49-51,52
Objective To study the quality difference of various processing methods about Angelica dahurica. Methods Samples were selected from different places, clean silt by washing and brushing, cut slices and cut blocks in equal division, dried and comminution, to determine total ash, ethanol thermal extract, imperatorin content and HPLC fingerprint similarity. Results The content of total ash was the lowest in “washed”and “washed & cut slice” sample, dilute ethanol thermal extract was the highest in“cut blocks”and“washed&cut blocks”sample, imperatorin content was the highest in“non-washed”and“non-washed & cut slice” sample. Conclusion Washed and cut process is not suitable in place of origin about Angelica dahurica.
10.Establishment and evaluation of employee satisfaction indicator system for thirteen general hospitals
Mingxiao WANG ; Yan GAO ; Wenjing ZHANG ; Zhongqiang CHEN ; Xin DING ; Jian LV ; Min CHEN
Chinese Journal of Hospital Administration 2011;27(10):742-745
Objective Establishing an employee satisfaction indicator system for tertiary hospitals in Beijing.Methods Evaluation indicators are built on theory research,and questionnaires are designed for survey.Such methods as principal component factor analysis,and verification factor analysis are called into play to test the construct validity and establish in the end the employee satisfaction indicators system.Results Such indicators comprise five grade-1 dimension and 34 grade-Ⅱ dimension,such as hospital management satisfaction indicator.Conclusion This self-designed scale ideally mirrors the employee satisfaction of tertiary hospitals in Beijing,proving the indicators to be objective and reasonable.