Objective To observe the clinical effects of topiramate together with low-dose ACTH and prednisone、vitamine B6、gamma globulin on infantile spasms. Methods 134 infantile spasms patients were selected and randomly divided into control group and treatment group, each group 67 patients. The control group was treated with sodium valproate. The treatment group received low-dose ACTH and prednisone、topiramate、vitamine B6 、gamma globulin. The two groups all completed a therapeutic period of 3 months. Results The effect of the treatment group compared with the control group has significantly statistical difference (P ＜ 0.05) ;the result of the treatment group'electroencephalogran compared with that of the control group also has significants difference (P ＜ 0.05). Conclusion The therapeutic effect of low-dose ACTH and prednisone、 topiramate、 vitamine B6、 gamma globulin together on infantile spasms was much better than just taking sodium valproate only.

Objective To explore the efficacy of traditional Chinese fumigating's treatment effect on infant's spasticity of cerebral palsy. Methods 92 patients with infant's spasticity of cerebral palsy were randomly divided into two groups: each group 46 patients. The control group received ordinary functional training and tuina therapies, and the treatment group except receiving functional training and tuina therapies ,they were given traditional Chinese fumigating additional,both groups were treated for 3 months. Results The muscular tension relieving extent in the treatment group is much better than that in the control group,and compared with the control group,there is significant statistical difference( t = 3. 11 ,P ＜0. 05) ;The overall efficacy was 86. 96% for the treatment group and 69. 57% for the control group. Between the two groups there were significant differences( x2 = 4. 09 ,P ＜ 0. 05). Conclusion Traditional Chinese fumigating could obviously relieve the muscular tension and improve clinical efficacy, and had a good clinical prospect.