1.Regulation of Glial Function by Noncoding RNA in Central Nervous System Disease.
Ying BAI ; Hui REN ; Liang BIAN ; You ZHOU ; Xinping WANG ; Zhongli XIONG ; Ziqi LIU ; Bing HAN ; Honghong YAO
Neuroscience Bulletin 2023;39(3):440-452
Non-coding RNAs (ncRNAs) are a class of functional RNAs that play critical roles in different diseases. NcRNAs include microRNAs, long ncRNAs, and circular RNAs. They are highly expressed in the brain and are involved in the regulation of physiological and pathophysiological processes of central nervous system (CNS) diseases. Mounting evidence indicates that ncRNAs play key roles in CNS diseases. Further elucidating the mechanisms of ncRNA underlying the process of regulating glial function that may lead to the identification of novel therapeutic targets for CNS diseases.
Humans
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RNA, Untranslated/genetics*
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MicroRNAs/genetics*
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RNA, Long Noncoding/genetics*
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RNA, Circular
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Central Nervous System Diseases/genetics*