Objective To study MR imaging features of bone marrow after priming.Methods 11 cases with lymphoma or myeloma alleviated after treatment were administration of recombinant human granulocyte colony-stimulating factor(rhG-CSF)injection.Two regions of bone marrow in L3 and iliac were followed up with T1WI,and STIR fat saturation before treatment(0 week),and 1 week,2 weeks and 4 weeks after treatment respectively.MRI features were observed by three experienced doctors independently and the average results acted as the final result.In the meantime,CNR of marrow and fat were calculated and paired sample test.Statistical process was performed in SPSS 10.0 for Windows.Results In comparison with 0 week,the signal intensity of bone marrow was no changed in all cases one week after intensive chemotherapy,slight high in 5 cases 2 weeks later and obvious low signal intensity in all cases three weeks after priming with rhG-CSF.In comparison with 0 week,CNR was no any different significance at 1 week,2 weeks and 4 weeks.Bone marrow changes in lumber and iliac were parallel except one case at 2 weeks and one case at 4 weeks.Conclusion Obvious low signal intensity of bone marrow is found three weeks after priming with rhG-CSF.

Objective To investigate clinical usefulness of intracranial lesions in pre-and post-operation by functional MRI with blood oxygen level dependent(BOLD)technique.Methods Common MRI and Motor hand area functional MRI examinations were performed in 45 patients (fMRI group)with intracranial lesions adjacent to the motor cortex before and after operation. As contrast group, 20 patients with occupying position lesions were made a routine MRI examination without fMRI before surgery. A 1.5 T signa super conducting system was employment (GE company ,America). Results The focal transactivation domain of cerebration was seen on fMRI in all cases of fMRI group. The cortical motor hand area shown displacement in 22 cases with abnormal size and shape and found not displacement in 23 cases. The distribution of transactivation domain was not changed in different disease . There was positive correlation between the distance from lesions to the domains and myodynamia in preoperation(r=0.553,P0.05). Our data indicated that there was negative correlation between the distance and the difference of myodynamia (r=-0.570,P

Objective To study the abnormal findings and metabolic alterations of the brain in chronic hepatic disease with MRI and 1H magnetic resonance spectroscopy (1H-MRS) for better understanding the clinical significance of pallidal hyperintensity and the role in the diagnosis and treatment of hepatic encephalopathy (HE) . Methods Brain MRI and 1H-MRS examination were performed in 50 patients with chronic hepatic disease and 20 healthy volunteers. The pallidus index (PI) was calculated and the height of resonance peaks of Glx was measured. The correlation between PI and Child/Pugh classification, and the association between blood ammonia and the spectroscopic alterations were studied. Pre-and post-therapeutic comparative study was also conducted in 5 cases with chronic HE. Results PI was gradually increased from healthy volunteers to patients with chronic hepatitis and liver cirrhosis (1.01?0.04, 1.06?0.09, and 1.18?0.09), and the differences in PI value among them were significant (F=22.294, P

Objective To evaluate the value of MRI in diagnosis of craniopharyngiomas. Methods MRI findings of 52 craniopharyngiomas were analyzed retrospectively and correlated with pathology.Results 37 cases of all 52 cases craniopharyngiomas were located on suprasellar. Craniopharyngioma fluid collections were found to be uniformly hyperintense on T 2-weighted images. However, on T 1-weighted images, the signal intensity of the fluid ranged from hypointense to hyperintense, reflecting the presence of pathological contents in these tumors. Conclusion MRI is an effective method in diagnosis craniopharyngioma due to its direct multiplanar capabilities and sensitive signal changes.

Objective To find the X-ray characteristic and diadynamic method in congenital defect of muscular layer in stomach wall. Methods Six cases confirmed by operation and pathology were collected,underwent eight standing abdomen plain films,underwent 5 decubitus abdomen plain films in 6 cases. Results The appearances in standing plain film of freeing gas under diaphragm, eventration of diaphragm, passing through the whole abdomen of gas and liquid plane, vanished gastriole were found in 6 cases. Superior border of liver was found in 4 cases.The appearances in decubitus abdomen plain films of abdominal distension, increasing gas gathered in umbilical region, vanshed fat line in abdominal wall were found in 4 cases. Conclusion Large part of typical cases could be diagnosis by x-ray and clinical appearance.

Objective To study the value in predicting the postoperative pulmonary function of the patient with quantitative MSCT.Methods 16-slice spiral CT scanning of lung was performed in 24 patients with pulmonary carcinoma before and after the operation during eupnea.Then the postoperative forced expiratory volume in one second(FEV1) and forced vital capacity(FVC)were calculated according to the preoperative lung capacity which was measured by quantitative MSCT,FEV1 and FVC which were measured by pulmonary functional test(PFT),then the results of FEV1 and FVC predicted by MSCT were compared with that two months later after operation.Results There was significant relativity in FEV1 and FVC between predicted by MSCT before operation and measured by PFT after operation ( P was 0.190 and 0.563 respectively).Conclusion Quantitative MSCT can predict the postoperative pulmonary function exactly,which provides dependable reference data for lung resection in the patients.with pulmonary carcinoma.

Objective To evaluate the applied value of MSCT lung volumes measurement in diagnosing chronic obstructive pulmonary disease(COPD).Methods 40 patients clinically diagnosed with COPD and 26 healthy volunteers as control group underwent MSCT chest CT scanning . The relevant indicators of lung volumes were measured and calculated in comparison with the indicators of clinical lung function . The accuracy and sensitivity of every indicator of lung volumes in forecasting and screening COPD by using ROC curve method were evaluated.Results There were significant differences between the control group and the COPD group in the full expiration volume(Vex),the full inspiration volume(Vin),Vex/Vin and the ratio of the change of lung volume(P

0.05).Singnificant difference of p21 positive rates was showed between tumor lack of blood supplies and arterial blood (?

Objective To study the relationship among SCT features of tumor margin and tumor size, immunohistochemical findings, grade of cell differentiation, and to explore the potency of tumor marginal features on multiphase spiral CT for evaluating biological behavior of small hepatocellular carcinoma (SHCC).Methods Multiphase spiral CT scans were performed in 30 patients with 33 lesions of SHCC (≤3.0 cm in diameter) confirmed histopathologically. Of these patients,26 were male and 4 were female. Immunohistochemical and HE staining were performed in surgical samples of all patients with SHCC. All samples' size was measured and the number of masses in each patient was counted.Results Of all masses, 6 were complete capsule, 15 incomplete capsule and 12 non-capsule. In multiple linear regression analysis, the pseudocapsula presentation and completion of SHCC on SCT were positively related with tumor size and VEGF expression, negatively with CD34 and p21, and were not in association with p53 and histological grade. Tumor size was the strongest contributor to pseudocapsula completion(R=0.5115), and then VEGF(R=0.2917), CD34(R=-0.2981) and p21(R=-0.2726), which had the similar standardized regression coefficients.Conclusion Tumor size is the strongest relative factor that influenced pseudocapsula presentation and completion of SHCC. VEGF always expressed positively in SHCC with complete pseudocapsula, and negatively in the group of SHCC with incomplete pseudocapsula or without pseudocapsula. In the group of SHCC with incomplete pseudocapsula or without pseudocapsula, p21 always express positively. Neither p53 expression nor histological grade is in association with the pseudocapsula presentation and completion of SHCC on SCT.

0.05). Homogenous or inhomogenous high signal in aplastic anemia were detected with decreased T 1 value. Homogenous iso-intensity was revealed in acute pure red cell aplasia with normal T 1 value. Aplastic anemia and acute pure red cell aplasia had a homogenous signal on T 2WI, their T 1 value showed significant difference (P