1.Clinical observation of acupuncture combined with acupoint injection in the treatment of post -stroke intractable hiccup
Ruchun ZHONG ; Xia LIU ; Hua GUO
Chinese Journal of Primary Medicine and Pharmacy 2017;24(4):550-554
Objective To observe the clinical therapeutic effect of acupuncture combined with acupoint injection in the treatment of post -stroke intractable hiccup.Methods 120 patients with post -stroke intractable hiccup were randomly divided into treatment group(60 cases)and control groups(60 cases)according to the digital table.The patients in the control group were treated with baclofen tablets and methloxetamine hydrochloride injection, and the patients in the treatment group were treated with acupuncture combined with acupoint injection therapy.The treating period was 1 week.The scores of hiccup symptoms,the total effective rate and side effect were recorded before and after the treatment in all patients.Results The scores of hiccup symptoms before treatment in the treatment group and the control group were (5.32 ±1.17)points and (5.25 ±0.65)points respectively,there was no statistically significant difference between the two groups(t =1.79,P =0.96).The scores of hiccup symptoms on the 1 day after treatment in the treatment group and the control group were (3.97 ±1.24)points and (3.85 ±1.02 )points respectively,there was no statistically significant difference between the two groups(t =1.93,P =0.48).The scores of hiccup symptoms on the 3 days after treatment in the treatment group and the control group were (2.80 ±0.73)points and (3.75 ±1.11)points respectively,there was significant difference between the two groups(t =2.66,P =0.00), that in the treatment group was lower than the control group.The scores of hiccup symptoms on the 5 days after treatment in the treatment group and the control group were (2.25 ±1.07)points and (3.43 ±0.81)points respec-tively,there was significant difference between the two groups(t =2.85,P =0.00),that in the treatment group was lower than the control group.The scores of hiccup symptoms on the 7 days after treatment in the treatment group and the control group were (1.27 ±0.66)points and (2.02 ±0.98)points respectively,there was significant difference between the two groups(t =1.07,P =0.00),that in the treatment group was lower than the control group.The total effective rates in the treatment group and the control group were 90%(54 /60)and 65%(39 /60)respectively,there was significant difference between the two groups(χ2 =10.75,P =0.00).The incidence rates of side effects in the treatment group and the control group were 1.7%(1 /60)and 6.7%(4 /60)respectively,there was no statistically significant difference between the two groups(χ2 =0.84,P =0.36).Conclusion Acupuncture combined with acu-point injection can significantly reduce the hiccup symptom score of post -stroke intractable hiccup patients on the 3, 5 and 7 days after treatment,and improve the total effective rate.
2.Clinical application of characteristic manifestation of MR diffusion weighted imaging at 3.0T in cerebral diseases
Journal of Practical Radiology 2015;(6):897-900
Objective To explore the value of characteristic manifestation of diffusion-weighted images at 3.0T MR system in cer-ebral disease.Methods 120 patients with cerebral disease diagnosed by MR diffusion-weighted images (fat suppression effect,T2 blackout effect,T2 shine-through effect,T2 washout effect)underwent routine MR scan,including echo planar imaging-diffusion weighted imaging (EPI-DWI)and apparent diffusion coefficient (ADC)map,whose characteristic manifestations of DWI were retro-spectively analyzed.Results 1 5 cases of lipoma and 8 cases without fat lesions were diagnosed with fat suppression effect.13 cases of acute cerebral hematoma,1 1 cases of hemorrhagic cerebral infarction and 1 6 cases of micro bleeding of missed diagnosis or small cavernous hemangioma were diagnosed with T2 blackout effect.1 5 cases of epidermoid cyst,5 cases of choroid plexus cyst were di-agnosed with T2 shine-through effect.1 5 cases of posterior reversible encephalopathy syndrome and 22 cases of brain tumor were di-agnosed with T2 washout effect.Conclusion Comprehensive use of the characteristic manifestation of EPI-DWI and ADC map can help the diagnosis of cerebral disease.
3.Adverse Drug Reactions of 6 Kinds of Quinolones
Ying LIU ; Hua ZHONG ; Beibei ZHU ; Juanjuan QIN ; Zhenhua LIU
Chinese Journal of Nosocomiology 2005;0(11):-
OBJECTIVE To analyze the adverse drug reactions of 6 kinds of quinolones in order to provide information for clinically rational use of drugs.METHODS The adverse drug reactions of quinolones such as norfloxacin,ofloxacin,levofloxacin,ciprofloxacin,fleroxacin and rufloxacin used in outpatients during Feb to May 2007 were collected and retrospectively analyzed.RESULTS The main adverse drug reactions were seen in gastrointestinal system,nervous system,immune system,respiratory system,urinary system etc.From them the symptoms of gastrointestinal system and nervous system were prominent.CONCLUSIONS In use of quinolones it should think highly to their adverse drug reactions.
4.Antimicrobial Use in Cardiac Surgical During Perioperative Period:An Investigation and Analysis
Ying LIU ; Hua ZHONG ; Dan SHEN ; Zhenhua LIU
Chinese Journal of Nosocomiology 2006;0(05):-
OBJECTIVE To find out the situation of antimicrobial usage in cardiac surgical perioperative period.METHODS The use of antimicrobials in cardiac surgical perioperative patients during Jan-Jun 2007,and the data of reasonable use of antibacterial were surveyed and evaluated.RESULTS Of the 276 patients,100.00% of them had received antimicrobials involving 12 kinds,59.78% of them used one kind only and 34.78% used two kinds antibiotics and 5.43% used more three kinds.CONCLUSIONS The use of antimicrobials in cardiac surgical perioperative period is reasonable and scientific.
5.Antibiotics Usage in Outpatients
Yang LIU ; Hua ZHONG ; Juanli L ; Yongmei ZHANG ; Ying LIU
Chinese Journal of Nosocomiology 2006;0(12):-
OBJECTIVE To investigate the use of antibiotics in our Outpatient Department during 2006-2007,and to analyze and evaluate the trend and rationality.METHODS The data about consumption quantity and consumption sum of antibiotics in our Outpatient Department during 2006-2007 were retrieved by means of computer management software in the department of pharmacy for the analysis of the clinical use of antibiotics using the method of defined daily dose(DDD).RESULTS Fluoro quinolones,cephalosporins and plant antibiotics have dominated the first places among the antibiotics used in our hospital,and the consumption of cephalosporins kept increasing year by year.CONCLUSIONS The use of antibiotics in our hospital should be further standardized to ensure the drug using safe,efficient and economic in our hospital.
6.Rational Usage of Antibiotics Prophylaxis in Department of Obstetrics and Gynecology During Perioperative Period
Yang LIU ; Hua ZHONG ; Juanli L ; Yongmei ZHANG ; Ying LIU
Chinese Journal of Nosocomiology 2009;0(13):-
OBJECTIVE To promote clinical rational use of antibiotic prophylaxis through surveying it in Obstetrics and Gynecology Department (OG) by pharmacists. METHODS Data of 223 cases using of antibiotic prophylaxis in OG were retrospectively analyzed. According to unreasonable use of antibiotic prophylaxis,the clinical pharmacists put out reasonable measures and directed treatment in succedent 206 patients. RESULTS The rate of unreasonable use of antibiotic prophylaxis in 223 cases was 100% and rate of infection after operation was 9.87%. After giving intervention,the rate of unreasonable use of antibiotic prophylaxis and infection were reduced to 3.88% and 1.46%,respectively (P
9.CT perfusion study of neck lymph nodes
Jin ZHONG ; Jun LIU ; Rui HUA ; Hui QIAO ; Yi GONG
Chinese Journal of Radiology 2011;45(1):46-49
Objective To study the CT perfusion features of various lymph nodes in the neck.Methods Dynamic perfusion CT scanning was performed in 83 neck lymph nodes proved by pathology,including tuberculosis lymph nodes, lymphoma and metastatic lymph nodes. The shapes, blood flow modes,and perfusion parameters of these lymph nodes were compared among 3 groups. Statistical analysis of L/T and CT perfusion parameters was performed by one-way ANOVA and LSD test. Results The values of MTT of tuberculosis lymph nodes, lymphoma and metastatic lymph nodes were (28. 13 ±5.08), (31.08 ±5.82),and ( 11.24 ±5.31 ) s,respectively. The MTT of metastatic lymph nodes was statistically lower than that of tuberculosis lymph nodes and lymphoma (P < 0. 05). Their frequencies of marginal blood flow were 5/9,4/19, and 39/55 (70. 9% ), respectively. The frequency of marginal blood flow in the tuberculosis lymph nodes and metastatic lymph nodes was statistically higher than that of lymphoma ( P < 0. 05 ). Their frequencies of central blood flow were 2/9, 11/19, and 9/55 (16.4%), respectively. The frequency of central blood flow in the lymphoma was statistically higher than that of tuberculosis lymph nodes and metastatic lymph nodes ( P < 0. 05 ). Their values of L/T were 1.82 ± 0. 32, 1. 80 ± 0. 39, and 1.84 ± 0. 36,(40. 98 ±6. 62) s,respectively. There were no significant differences in L/T, BF, BV and TTP among tuberculosis lymph nodes, lymphoma and metastatic lymph nodes( P > 0. 05 ). Conclusion CT perfusion,especially combination functional imaging with perfusion images may be helpful in judging the nature of neck lymph nodes.
10.The effect of Glutamine on the shape of residual intestine and colon in rats with short bowel syndrome
Hanrong LIU ; Tianfang HUA ; Fuquan ZHONG ; Jincheng KONG
Parenteral & Enteral Nutrition 2001;8(1):25-27
Objectives:To investigate the effect of glutamine on the shape of residual intestine and colon in rats with short bowel syndrome. Methods:23 male Sprague-Dawley rats,underwent a 80% small bowel resection,were randomly divided into three groups:food group(n=8) rats,fed rat chow and water libitum after operation;TPN group(n=8),infused with Gln-supplied TPN;and normal control group.On seventh day after operation,rats were weighted and remaining jejunum、remaining ileum and colon were harvested for histological observation(light microscopy and electron microscopy). Results:There was significant difference in rat average weight between food group and Gln group after operation.Jejunal mucosal villus height(VH) and mucosal thickness(MT) and ileal mucosal VH in food group were significantly increased than those in control group.Jejunal mucosal VH and MT in control group were significantly higher than in TPN group.Ileal mucosal crypt depth(CD) and MT in control group were also significantly higher than in TPN group.Jejunal and ileal mucosal VH、CD and MT in Gln group were significantly higher than in TPN group.Colonic MT in food group was significantly higher than in control group.Colonic MT in Gln group was significantly bigger than in TPN group. Conclusions:After 80% intestinal resection,the remaining intestine can develop the adaptation,but the adaptation is incomplete.TPN therapy can maintain body weight,but only TPN can not result in the adaption.Gln-supplied TPN can stop the remaining itestinal mucosal atrophy,and promote the remaining intestinal adaptation and colonic mucosal hypertrophy.