2.Study on the role of local immunity in the female genital tract with nongonococcal urethritis
Yan LI ; Quan-Zhong LIU ;
Chinese Journal of Infectious Diseases 2001;0(06):-
Objective To study the role of local immunity in the female genital tract with non- gonococcal urethritis(NGU).Methods Forty-four cervical secretions from patients with NGU were collected.After treatment with Azithromycin,22 cases were followed up.One month later,pathogen was eliminated in 15 patients.Another 27 un-infected people were included in our study.The level of secretory immunoglobulin A(SIgA)was detected using the automatic special protein analysor,and interferon-?(IFN-?)was quantified by enzyme-linked immunosorbent assay(ELISA).All data were analyzed with ANOVA.Results The levels of SIgA and IFN-?in NGU infected group were(34.29?15.92)mg/L and(97.13?24.00)ng/L respectively,while those of uninfected group were(47.57?19.61)mg/L and(120.71?33.78)ng/L,respectively(all P0.05).Conclusions SIgA and IFN-?secreted by genital tract mucosa may help pre- vent and resist the local NGU infection.However,the effect is limited,and is insufficient to eliminate infection completely and prevent reinfection.
3.Observation of the effect of comprehensive rehabilitation on patients with stroke in different periods
Chinese Journal of Rehabilitation Theory and Practice 2002;8(3):166-166
ObjectiveTo observe the effect of comprehensive rehabilitation treatment on clinical nerve function deficiency (CNFD) and activities of daily living (ADL) of the patients with stroke. Methods45 stroke sufferers from different period were divided into three groups (1st group: in one month; 2nd group: one to six months; 3rd group: over six months). Before and after the comprehensive rehabilitation treatment was given, the CNFD, ADL and clinical effect were assessed.ResultsAfter comprehensive rehabilitation treatment, the CNFD of 1st group, and the ADL score of 1st group and 2nd group were improved significantly, and the 1st group's was better than the others. The total effective rate also increased in 1st and 2nd group. Conclusions Early rehabilitation treatment can improve the patient's neural motion function and the activities of daily living.
5.Study on the relationship of working family conflict and result varience in Wanzhou district of Chongqing
Xiaoqin ZHONG ; Jishu TIAN ; Li YAN
Chinese Journal of Practical Nursing 2010;26(5):11-14
Objective To tudy the relationship of working family conflict and working pressure, symptom, working satisfaction, job burnout, and working achievement in Wanzhou district of Chongqing. Methods 1094 nurses were randomly surveyed in this study. Nursing woking family conflict scale, working pressure scale, symptom, working satisfaction scale, job burnout, and working achievement-related data were collected from clinical nursing units. Results High working family conflict had been ob-served in nurses of Wanzhou district of Chongqing. Nurses individual health had been greatly influenced by working family con-filct, which not influencing working achievement. Conclusions It is important to keep individual mental health through relieving job family conflict and taking more care for nurse population in family conflict.
6.Effect of ritodrine hydrochloride combined with radix salviae miltiorrhizae on fetal growth restriction
Honglian YAN ; Li LIU ; Yanping ZHONG
Chinese Journal of Primary Medicine and Pharmacy 2008;15(7):1149-1150
Objective Ritodrine hydrochloride(RH) combined with radix salviae mihiorrhisa(RSM) is ap- plied to treat fetal growth ristriction(FGR). Curative effect was recorded during observation. Methods 62 pregnant women with slowly growing fetuses were divided into two groups randomly. Group A(test group) :including 31 preg- nant women who received RH combined with RSM treatment. Group B(control group) :including the other 31 preg- nant women who only received RSM treatment. Group B received 250ml of fat emulsion injection. One time every three days within one week. At the same time,gronp B also received injection of 500ml 10 % dextrose, coenzyme A 100U ,ATP 40mg,vitamin C 2g,dextran-40 and compound salvia injection 10ml one time a day,ten days in all. Be- sides the above-mentioned medicament for group B, group A received RH 100ml injection every day. Ten days was a period of treatment. After the treatment, uterine height, abdominal circumference, weight were measured and bipari- etal diameter, head circumference, abdominal circumference were checked by B-type ultrasonic inspection. After birth,weight of the baby and weight of placenta were measured too. Results Measurement indexes from group A, weight of the new-born baby and weight of placenta are obviously higher than those from group B. Conclusion RH combined with RSM can obviously extend blood vessel, loose placenta, improve blood circulation, accelerate cell metabolism, make microeirculation better, reduce permeability of capillary vessel, keep placenta's function and help foetus' growth.
7.Application of clinical pathway in uterectomy patients
Qiulian ZHONG ; Yan LI ; Xia CHEN
Chinese Journal of Practical Nursing 2010;26(14):30-32
Objective Through application of clinical pathway in hospitalization patients undergoing uterectomy, we aimed to study the efficacy of clinical pathway in uterectomy patients. Methods 120 patients randomly sampled into the experimental group and the control group with 60 in each. The experimental group received diagnosis, treatment, nursing and rehabilitation according to the clinical pathway table, patients in the control group received routine nursing interventions. The average hospitalization days, medical costs, patient satisfaction degree, disease cognition, first exercise time after operation and medical disputes were compared between the two groups. Results The average hospitalization days and hospitalization costs of the experimental group were obviously lower than those in the control group, patients' satisfaction degree, knowledge of health and first functional exercise time in the experimental group were better than those of the control group, while the medical disputes in the experimental group were obviously de -creased in the experimental group. Conclusions Application of clinical pathway in nursing care for uterectomy patients can effectively decrease hospitalization days, medical costs and disputes. It is also helpful for patients to cooperate with doctors in diagnosis, treatment, nursing, thus increase the satisfaction degree of patients, ensure the reasonable use of medical resources and promote the sustainable improvement of nursing quality.
8.Clinical research on autologous valved pericardial patch in the correction surgery of tetralogy of fallot
Huabao LI ; Zhongya YAN ; Zhong LU
Acta Universitatis Medicinalis Anhui 2015;50(10):1460-1463
Objective To investigate the activity of autologous pericardial patch treated by distilled water in right ventricular outflow tract reconstruction of tetralogy of fallot,and to evaluate its clinical effect. Methods The study used 125 patients who had applied correction surgery of tetralogy of fallot and autologous pericardial patch treated by distilled water in the right ventricular outflow reconstruction. 39 cases used fresh autologous pericardial patches,and 86 cases used autologous valved pericardial patch. The degree of insufficiency and activity of the pulmonary valve were compared. Results The mean follow-up time was ( 63 ± 8 ) months in fresh autologous pericardial patches group, while (55 ± 7) months in valved patch group. No significant difference was found in age, body surface area, heart rate, pulmonary artery diameter, cardiopulmonary bypass time and priming volume postoperative between the two groups. The exacerbations of pulmonary valve insufficiency and activity in fresh autologous pericardial patches group were significantly higher than in valved patch group. Conclusion Autologous pericardial patch treated by distilled water was beneficial in right ventricular outflow tract reconstruction of tetralogy of fallot. It reduced pulmo-nary valve insufficiency and sclerosis after the correction surgery and showed good mid-term clinical results .
9.Fabricating periodontal tissue engineering compound by gene modified gingival fibroblasts and acellular dermal matrix
Quan ZHONG ; Yanfen LI ; Fuhua YAN
Chinese Journal of Tissue Engineering Research 2015;(43):6906-6912
BACKGROUND:Previous studies have found that human platelet-derived growth factor-B (PDGF-B)-transfected gingival fibroblasts are capable of rapid proliferationin vitro, which can secrete platelet-derived growth factor BB proteins. OBJECTIVE:To explore the ability of PDGF-B-modified gingival fibroblasts in the acelular dermal matrixin vivo to form periodontal tissue engineering compound. METHODS: Gingival fibroblasts from Beagle dogs transfected with or without PDGF-B gene were implanted into the acelular dermal matrix. Cel growth on the acelular dermal matrix was observed. PDGF-B gene-transfected gingival fibroblasts/acelular dermal matrix composite (experimental group), gingival fibrobalsts/acelular dermal matrix composite (control group) and acelular dermal matrix (blank group) were implanted subcutaneously into the nude mice, respectively. At 2, 4, 8 weeks after implantation, skin tissues were taken and observed histologicaly. RESULTS AND CONCLUSION: PDGF-B gene-modified gingival fibroblasts and non-transfected gingival fibroblasts both grew and proliferated wel in the acelular dermal matrix. At 8 weeks after implantation, in the blank group, the surrounding cels largely entered into the acelular dermal matrix, but produce less new colagen fibers, and the cels only grew on the original colagen scaffold; in the control group, a great amount of colagen fibers formed, the original colagen fibers in the acelular dermal matrix were replaced by newly formed colagens, but the original colagen structure was reserved; in the experimental group, a large scale of permineralization formed, and mineralized nodes were arranged along the original colagen scaffold. These findings indicate that PDGF-B gene modified gingival fibroblasts can acquire osteoplastic abilities in the acelular dermal matrix in vivo.
10.Gd-DTPA Enhancement MR Angiography of Intracranial Occuping and Vascular Diseases
Dejiong LI ; Ping ZHONG ; Yan XIA
Chinese Journal of Medical Imaging Technology 2001;17(3):208-209
Purpose To investigate the diagnostic valuation of Gd-DTPA enhancement MRA in intracranial occuping and vescular diseases. Methods Gd-DTPA MRA(63 cases), MRA without Gd-DTPA(16 cases)as a control group was performed with Elscint Prestige 2.0T MR,MRA. 56 cases were proved by operation or pathology, 7 cases were proved by clinical observation. Results The shape of aneurysms, the feeding arteries, the draining veins of AVM and diploe angioma, the feeding arteries of occuping were clearly showed by Gd-DTPA enhancement MRA and were not showed by MRA without Gd-DTPA.There wasn't much difference between cavernous angioma with Gd-DTPA enhancement MRA and MRA without Gd-DTPA in the shape and blood supply of cavernous angioma. Conclusion Gd-DTPA enhancement MRA is useful and worthy for showing blood circulation of intracranial occuping and vascular diseases.