1.Effects of adriamycin on cultured mouse podocytes VEGF expressions and the potential protective effects of dexamethasone.
Xiao-zhong LI ; Hai-tao YUAN ; Xue-guang ZHANG
Chinese Journal of Pediatrics 2003;41(2):146-146
Animals
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Antibiotics, Antineoplastic
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pharmacology
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Blotting, Northern
;
Cells, Cultured
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Dexamethasone
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pharmacology
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Doxorubicin
;
pharmacology
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Enzyme-Linked Immunosorbent Assay
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Gene Expression Regulation
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drug effects
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Glucocorticoids
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pharmacology
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Kidney Glomerulus
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cytology
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drug effects
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metabolism
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Mice
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RNA, Messenger
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drug effects
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genetics
;
metabolism
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Vascular Endothelial Growth Factor A
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genetics
;
metabolism
2.Ulnar impaction syndrome caused by manipulating of keyboard and mouse.
Hai-tao SONG ; Zhong-wu REN ; Lian-cheng LIU
Chinese Journal of Industrial Hygiene and Occupational Diseases 2009;27(12):769-771
Adolescent
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Adult
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Female
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Humans
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Male
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Middle Aged
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Occupational Diseases
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diagnosis
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etiology
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Ulna
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injuries
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Wrist Injuries
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diagnosis
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etiology
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Young Adult
3.Early diagnosis of ulnar impaction syndrome
Hai-Tao SONG ; Wan-Cheng TIAN ; Quan-Zhong LU ;
Chinese Journal of Orthopaedic Trauma 2004;0(08):-
Objective To explore early diagnostic methods for ulnar impaction syndrome on the basis of suggested criteria.Methods From December 1998 to December 2004,123 cases complained of ulnar pain.They were checked and diagnosed according to the criteria of Yu-dong Gu,and especially,the results of wrist MRL Forty-eight of them were diagnosed as ulnar impactinn syndrome.A retrospective study was done to analyze the char- acteristies of X-ray and MRI in examining ulnar impaction syndrome,clinical symptoms of the wrist,and the association between Chun & Palmer's scoring systems and imaging manifestations.Results Most of the cases of ulnar impaction syndrome had positive lunar variance (68.8%).Carpal avascular necrosis was found in about 27.1% of the cases through X-ray examination of the wrist,64.7% of whom were lunar osteonecrosis.Abnormal changes in signal intensity occurred in the MRI findings of the syndrome cases.The carpal necrosis was always located at the ulnar side of lunare or (and) at the waist and bottom of triquetrum.There was a close relationship between clinical symptoms and Chun & Palmer's grading systems and carpal imaging,MRI in particular Conclusion Early diagnosis of ulnar impaction syndrome can be made easily on the basis of deep understanding of the syndrome,clinical symptoms,and findings of imaging,especially MRI.
4.Research status, development and utilization of traditional Dai medicine in China.
Bao-Zhong DUAN ; Jiang XU ; Hai-Tao LI ; Chen SHI-LIN
China Journal of Chinese Materia Medica 2015;40(1):18-23
OBJECTIVETo provide a reference for the development and utilization of Dai medicine by investigate the present situation and existing problems of traditional Dai medicine.
METHODCombined with the previous relevant investigations and literature in the field, the key and the development direction of traditional Dai medicine were analyzed.
RESULTThe textual research, history, species, distribution, endangered resources, protection status etc. were elaborated and the key strategy of further investigation was expounded.
CONCLUSIONDai medicine resources should strengthen the basic research, such as the protection of traditional knowledge, the textual research, quality standard, chemical composition, biological activity, exploration of medicinal resources, especially monographic study on protection of major endangered medicinal resources should be intensified, which will be rise the level of development and utilization of Dai medicine resources.
China ; ethnology ; Conservation of Natural Resources ; history ; Drugs, Chinese Herbal ; history ; pharmacology ; History, 20th Century ; History, Ancient ; Medicine, Chinese Traditional ; history ; Plants, Medicinal ; growth & development
5.Statistical analysis of monitoring data regarding urinary iodine level of infants and babies in Ningxia in 2009
Hui-zhong, WU ; Li, LI ; Wen-ning, YOU ; Hai-tao, GAO
Chinese Journal of Endemiology 2010;29(4):420-422
Objective To determine urinary iodine level among babies and infants aged 0-30 months in Ningxia, and to provide scientific evidence for strengthening iodine supplement or decreasing salt iodine level in special population. Methods One thousand four hundred and eighty-three babies and infants were selected randomly from 664 administrative villages of 22 counties (city or district) by two-stage sampling method. Urinary iodine was tested with the arsenic cerium catalysis spectrophotometric method and related influencing factors were analyzed. Results Urinary iodine median was 216.5 μg/L of the whole autonomous region, and the value that was lower than 100 μg/L, accounted for 19.1%(283/1483), 100 - 300 μg/L accounted for 49.3%(731/1483), higher than 300 μg/L, accounted for 31.6% (469/1483). Urinary iodine median was in 130.6 - 328.4 μg/L of all counties, which was higher than 100 μg/L. The urinary iodine median of men(223.2 μg/L) was slightly higher than that(210.2 μg/L) of female, no significant difference was observed(Z = - 1.76, P > 0.05). Urinary iodine level changed little when child was younger than one year old(Z = - 0.624, P > 0.05). Then the value dropped gradually after one year old(χ2 = 13.59, P < 0.05), decreased with age by month, and the proportion of the value smaller than 100 μg/L was increased gradually. Urinary iodine level(257.5 μg/L) of child whose mother had taken iodine oil pills was higher than that (221.2 μg/L) of child whose mother had significant difference was observed(Z = - 2.54, P < 0.05). The urinary iodine level (239.1 μg/L) of child who received breast feeding was higher than that (204.2 μg/L) of child without breast feeding among one year old and younger infants and babies, significant difference was observed (Z = - 2.74, P < 0.05). Conclusions Current iodine level in iodized salt is probably higher than suitable in Ningxia, and the value could be decreased. It is unnecessary to strengthen iodine supplement procedure in special population other than people in Xiji county.
6.Growth activity of osteoblast on a novel strontium incorporated calcium sulfate.
Chun-Li ZHANG ; Yan-Tao ZHAO ; Shu-Xun HOU ; Hong-Bin ZHONG ; Zhong-Hai LI ; Yan LIU ; Ying ZHOU
China Journal of Orthopaedics and Traumatology 2014;27(5):415-418
OBJECTIVETo investigate the growth activity of osteoblast on a novel strontium incorporated calcium sulfate and make comparison with normal calcium sulfate material.
METHODSOsteoblast was inoculated on samples and cell proliferation was measured on the 1st, 3rd, 5th days, and the activities of ALP and osteocalcin were observed on the 5th day. And microcosmic morphology of osteoblast was observed by scanning electron microscopy(SEM).
RESULTSOsteoblast grows robustly on tested material. Cell quantity on the surface of novel material was obviously higher than normal calcium sulfate material (P < 0.05). The activity of ALP and osteocalcin on novel material was 57.8% and 40.2% higher than on normal calcium sulfate material respectively (P < 0.05). On strontium incorporated surface, osteoblast spread well. Cells were polygonal with abundant cytoplasm and the morphology was active.
CONCLUSIONStrontium incorporated calcium sulfate can sustain robust growth activity of osteoblast, which is promising to be used for bone substitute materials.
3T3 Cells ; Alkaline Phosphatase ; metabolism ; Animals ; Bone Substitutes ; chemistry ; pharmacology ; Calcium Sulfate ; chemistry ; pharmacology ; Cell Proliferation ; drug effects ; Mice ; Osteoblasts ; cytology ; drug effects ; metabolism ; Osteocalcin ; metabolism ; Strontium ; chemistry
7.Cardiac Ultrastructure and Changes of HSP70 and HIF-1α Expression in Electric Shock Death Rats.
Guo-zhong ZHANG ; Rui-li LI ; Guo-wei FENG ; Hai-tao BI ; Song-jun WANG ; Bin CONG ; Min ZUO
Journal of Forensic Medicine 2015;31(4):262-265
OBJECTIVE:
To observe cardiac ultrastructure and the expression of heat shock protein 70 (HSP70) and hypoxia inducible factor-lα (HIF-lα) in electric shock death rats and to explore the application of these indexes as the basis of medical identification in electric shock death.
METHODS:
Seventy-two SD rats were randomly divided into electric shock death group, postmortem electric shock group and the control group. The changes of myocardial ultrastructure were observed by transmission electron microscope, and the expressions of myocardial HSP70 and HIF-1α were observed by immunohistochemical technology.
RESULTS:
Myocardial myofibril fracture, mitochondrial cristae and membrane dissolution, and disordered arrangement of Z lines and M lines were observed in electric shock rats. HSP70 and HIF-lα were strong positive expressions in the electric shock death group, significantly compared with the control and postmortem electric shock groups (P < 0.05).
CONCLUSION
The expressions of HSP70 and HIF-lα were obviously increased in electric shock death group, which may be used as the diagnostic indicator of electric shock death.
Animals
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Death
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HSP70 Heat-Shock Proteins/metabolism*
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Hypoxia-Inducible Factor 1, alpha Subunit/metabolism*
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Myocardium/pathology*
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Rats
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Rats, Sprague-Dawley
8.Anatomical observation on surgical spaces related to laparoscopic right hemicolectomy.
Ce ZHANG ; Hai-tao YU ; Zi-hai DING ; Guo-xin LI ; Shi-zhen ZHONG
Chinese Journal of Gastrointestinal Surgery 2012;15(8):819-823
OBJECTIVETo explore regional anatomy of fasciae and spaces related to laparoscopic right hemicolectomy (LRC).
METHODSSeven cadavers and 49 patients undergoing LRC for cancer were observed. Computed tomography (CT) images of patients and healthy individuals were reviewed.
RESULTSBetween ascending mesocolon and prerenal fascia (PRF), there was a right retrocolic space (RRCS), which communicated in all directions. Anterior, posterior, medial, lateral, cranial, and caudal boundaries of the RRCS were ascending mesocolon, PRF, superior mesenteric vein, peritoneal reflexion at right paracolic sulcus, inferior margin of transverse part of duodenum, and inferior margin of the mesentery root, respectively. Between transverse mesocolon and pancreas and duodenum, there was a transverse retrocolic space (TRCS), which was bounded cranially by root of transverse mesocolon. On CT images of healthy individuals, PRF was noted as slender line of middle density, continuing to transverse fascia, and the retrocolic spaces were unidentifiable. For patients with right colon cancer, PRF and right retrocolic space might be easier to be identified.
CONCLUSIONSThe RRCS and the TRCS are natural surgical spaces. The PRF is natural surgical plane in LRC for cancer.
Adult ; Colectomy ; methods ; Colon ; anatomy & histology ; pathology ; Colonic Neoplasms ; pathology ; surgery ; Female ; Humans ; Laparoscopy ; methods ; Male ; Middle Aged ; Young Adult
9.Acupuncture treatment of regulating spirit, activating blood and relieving pain for thalamic pain.
Xue ZHANG ; Xiao-Nong FAN ; Luo DING ; Hai-Tao ZHANG ; Lian-Zhong WU ; Hai-Rong WANG
Chinese Acupuncture & Moxibustion 2010;30(5):367-370
OBJECTIVETo compare the clinical effect of acupuncture treatment and western medicine Carbamazepine for thalamic pain.
METHODSCrossover trial design was used, 11 cases diagnosed as thalamic pain were randomly divided into two groups according to the mini-unbalance-index method, group I (with 6 cases received acupuncture first and then western medicine) and group II (with 5 cases received western medicine first and then acupuncture). When the effects were evaluated, the two groups were named as acupuncture group and western medicine group, 11 cases in each group. The method of clearing away the heart fire, regulating the spirit, activating blood and relieving pain was adopted in acupuncture treatment, Ximen (PC 4), Yinxi (HT 6), Xuehai (SP 10) and Zhaohai (KI 6) were selected; the western medicine group was treated with oral administration of Carbamazepine, and one course as well as the eluting period were both 10 days. The effects were evaluated with visual analogue scale (VAS) and evaluation scale of Anderson Cancer Center pain in US (MD Pain Evaluation value) respectively.
RESULTSThe VAS and MD value in two groups were obviously decreased after treatment (both P < 0.05), while there was no significant difference between two groups; the markedly effective rate of pain relieving in acupuncture group was 63.6% (7/11), which was higher than that of 36.4% (4/11) in western medicine group, but there was no significant difference between two groups.
CONCLUSIONAcupuncture treatment of regulating spirit, activating blood and relieving pain has a better therapeutic effect for thalamic pain, and can reach to the same therapeutic effect with western medicine Carbamazepine.
Acupuncture Therapy ; Adult ; Aged ; Blood Circulation ; Carbamazepine ; therapeutic use ; Cross-Over Studies ; Female ; Humans ; Male ; Medicine, Chinese Traditional ; Middle Aged ; Pain ; physiopathology ; Pain Management ; Pain Measurement ; Spirituality ; Thalamus ; physiopathology
10.Original plant identification of Dai nationality herb "Daibaijie".
Hai-Tao LI ; Li-Ping KANG ; Bao-Lin GUO ; Zhong-Lian ZHANG ; Yan-Hong GUAN ; Xu PANG ; Chao-Zhong PENG ; Bai-Ping MA ; Li-Xia ZHANG
China Journal of Chinese Materia Medica 2014;39(8):1525-1529
OBJECTIVETo identify the original plant of "Daibaijie", commonly used Dai herb.
METHODThe literature review, morphology and anatomy, pharmacognosy, molecular biology, chemistry were used to analysis.
RESULTDaibaijie's historical scientific name, Dregea sinensis Hemsl., was mistakenly given "Daibaijie" and D. sinensis have significant differences from the distribution, morphology and anatomy, pharmacognosy, molecular biology and chemical composition. "Daibaijie" matches with the characteristics of Marsdenia tenacissima (Roxb.) Moon in Flora of China in English.
CONCLUSIONDaibaijie's original plant is M. tenacissima (Roxb.) Moon. The description and illustration of M. tenacissima (Roxb.) Moon in Flora of China in China are wrong. The illustration of M. tenacissima in Flora of China in English is wrong too.
China ; ethnology ; Herbal Medicine ; Marsdenia ; anatomy & histology ; classification ; Medicine, Chinese Traditional ; Plant Components, Aerial ; anatomy & histology ; classification