80 male Wistar mice were randomly divided into 8 groups. The effects of the big black Ant preparations (alias Xuanju ) obtained in different ways and their compound preparations in different dosages on the amount of RNA and DNA in the testes of mice were observed. After administration of the preparations for 21 days, the mice were decapitated and the testes were excised and weighed. The RNA and DNA in the testes were isolated andpurified with the method of SDS- phenol and their amounts were measured with UV-VIS spectrophotometry. The results showed that the mean testes weight in the experimental groups was significantly higher than that in the control group (P

Deep venous thrombosis in the lower extremities is a very common disease clinically and can greatly affect people in their work and life without proper treatment promptly.The author reviewed the etiology,diagnosis,preventive measures and the synthetic therapies for dealing the deep venous thrombosis in the lower extremities,especially concerning the interventional radiology.

Based on ESI web of science,the article analyzed papers published by three Medical Schools from 2001 to 2012 in terms of volume of publication,cited times,discipline distribution,au thors and cooperation,and determined each factor's impact on research output and performance.Sug gestions and advice were given to enhance the overall basic medical science research level.

Humans ; Occupational Diseases ; prevention & control ; Occupational Health Services ; organization & administration ; Risk Assessment ; Workplace

0.05). Retention rate was 97.5% (117/120) in Gyn IUD group and 90.0% (108/120) in ML IUD group, with statistically significant difference (P

Objective To study the value of B-cell activating factor (BAFF) expression levels in the diagnosis and prog-nosis of children with idiopathic thrombocytopenic purpura. Methods Children with idiopathic thrombocytopenic purpura (ITP) admitted to our hospital from September 2011 to September 2013 were enrolled in observation group, and healthy check-up chil-dren during the same period were enrolled as controls. The serum levels of B-cell activating factor, platelet antibodies (PAIgG, PAIgM, PAIgA) and platelet count were detected, and curative effect in children with ITP was observed. Results The BAFF, PAIgG, PAIgM and PAIgA levels were higher and platelet count were less in both acute and chronic ITP children than those in normal controls. The difference was signiifcant (P<0.05). The results of linear regression analysis indicated that BAFF levels were positively correlated with PAIgG, PAIgM and PAIgA levels (β=1.87~2.25, P<0.05), and were negatively correlated with platelet count (β=-2.42, P<0.05). Meanwhile, BAFF levels were negatively correlated with curative effect in ITP children (β=-1.88, P<0.05). When the value of BAFF was 1.35, the sensitivity for predicting effective treatment was 0.84 and the speciifcity was 0.75. The area under the ROC curve was 0.85 (95%CI:0.73~0.98, P=0.000). Conclusions The serum BAFF expression was increased and closely related to the level of antiplatelet antibody, platelet count and treatment effect in ITP children, and therefore, was a good indicator for the diagnosis and prognosis of ITP.

Dystonia is a syndrome which is characterized by sustained muscle contractions, producing twisting, repetitive, and patterned movements, or abnormal postures. According to genetic basis, dystonia is classified into 13 subtypes. We mainly discussed two subtypes, DYT1 and DYT5, in this review. Early-onset primary dystonia is caused by the mutation of DYT1 gene, which leads to TORSINA abnormal. GTP cyclohydrolase 1 (GTPCH1)-deficient DRD(DYT5) is caused by the mutations of GCH1 gene. By genetic testing, we can confirm clinical diagnosis of each subtype and develop prenatal diagnosis for it.

Objective To explore the effect of in-and out-hospital continued nursing care on emotional state and health behavior of breast cancer patients undergoing chemotherapy after radical mastectomy.Methods Forty breast cancer patients undergoing radical chemotherapy in the oncology department of our hospital during March 2012 to February 2014 were put into the study group and another forty patients from the same department during March 2014 to February 2016 into the control group.The control group received traditional nursing care,while the study group in-and out-hospital continued nursing care mode.The health promotion lifestyle assessment scale (HPLP-Ⅱ),self rating anxiety scale (SAS) and self rating depression scale (SDS) were used for the evaluation before intervention and 2 months after the intervention.Results After intervention,there were no significant differences in the total scores on health behaviors and the dimensions,anxiety and depression (P＞0.05).Two moths after intervention,the scores on health behaviors and the dimensions in the study were all significantly higher than those in the control group and the scores on anxiety and depression were significantly lower (P＜0.05).Conclusion The in-and out-hospital continued nursing mode is beneficial for the breast cancer patients undergoing chemotherapy after radical mastectomy to adjust their emotions and improve their health behaviors.

OBJECTIVE:To evaluate therapuetic efficacy and toxic reaction of 2 therapuetic regimens for 56 cases of bone me-tastasis of cervical cancer. METHODS:56 cases of bone metastasis of cervical cancer with complete information were collected ret-rospectively and randomly divided into radiochemotherapy group(31 cases)and diphosphonate group(25 cases). Radiochemothera-py group was given radiotherapy,chemotherapy and diphosphonate;diphosphonate group was given palliative symptomatic treat-ment of diphosphonate;a treatment course lasted for 3-4 weeks,and both groups received 3 courses of treatment. Average survival time,survival quality and toxic reaction were comparison in 2 groups. RESULTS:After bone metastasis of cervical cancer,the av-erage survival time of radiochemotherapy group was 17 months (95%CI:9.1-24.9),and that of diphosphonate group was 19 months (95%CI:2.4-35.6);3 years later,the survival rate of radiochemotherapy group was 16.1%,and that of diphosphonate group was 16.0%,there was no statistical significance(P=0.820). To compared KPS after 3 treatment courses,the improvement rate of radiochemotherapy group(22.6%)was significantly lower than that of diphosphonate group(40.0%),with statistical signif-icance (χ2=4.36,P<0.05). Toxic reaction of radiochemotherapy group was more significant than that of diphosphonate group. CONCLUSIONS:Diphosphonate has little effect on survial quality and slight toxic reaction. It is worthy of spreading in some pa-tients with advanced,elderly and reccurred bone metastasis of cervical cancer.

The determination of fraxetin A and fraxetin B in Cortex Fraxini have been carried out by HPLC on the stationary phase:octodecyl-silicohydride bonded silica gel column. The mobile phase was methanol-water(24:76). The detection wavelength was at 348nm. There was a good linear relationship in a concentration range of 16?g/ml~176?g/ml. The correlation coefficients were 0. 9995 and 0. 9994,respectively. The recovery of the added sample were 99. 1 ?1. 5% (n=5) for fraxetin A and 99.8?2. 5%(n=5) for fraxetin B. This method showed 0. 8% of within-day accuracy and 6. 2% of between-day accuracy,involving the advantages of simplicity,quickness and accuracy.