Objective:To observe the efficacy of A clotrimazole combined with ultrasonic atomization of ozone in the treatment of candidal vaginitis. Methods:Totally 200 cases of candidal vaginitis were divided into the observation group and the control group with 100 cases in each. The control group was given A clotrimazole creams through vaginal administration, qd, while the observation group was treated by ultrasonic atomization of ozone additionally, qd, 15min per time with five times. The clinical efficacy and the recurrence rate after 6 months of the two groups were compared. Before the treatment and in the first and fourth week after the treatment, vaginal secretion bacterial culture was performed and pH value was detected. Results:The cure rate and the total effective rate of the observa-tion group was 88% and 98%, respectively, which was significantly higher than that of the control group (69% and 82%, respective-ly, P<0. 05). After the 6-month follow-up, the recurrence rate was 1. 0% in the observation group (1/98), which was significantly lower than that in the control group [7. 3%(6/82),P<0. 05]. After the treatment, the vaginal pH value in the observation group was reduced notably and the number of lactobacillus was increased significantly(P<0. 05), while those in the control group were without significant changes (P>0. 05). Conclusion:A clotrimazole combined with ultrasonic atomization of ozone in the treatment of candidal vaginitis can improve the therapeutic effect.

One case of schistosomiasis got drug fever after taking praziquantel.

Objective To find out the quality of brain function electromagnetic adjuvant therapy for neurosis treatment.Methods 100 patients were randomly divided into two groups,study group(50 cases)was treated for brain function by electromagnetic therapy with the drug treatment,and only drug treatment was used for the control group(50 cases).The psychological symptom checklist(SCL-90)and Pittsburgh Sleep Quality Index Scale(PSQI)were used to assess clinical symptoms and sleep quality of the two groups before and after therapy of 30 days,and the scale results were compared.Results After treatment,somatization,interpersonal sensitivity,anxiety,depression,hostility,phobia,obsessive-compulsive disorder,paranoid and psychotic items score of SCL-90 scale of study group was significantly lower than the scale before treatment(all P ＜0.05);after treatment somatization and anxiety item scores of SCL-90 scale of study group were significantly lower than the control group(all P ＜0.05).After treatment PSQI total scale score,sleep latency,sleep continuity,sleep efficiency,the use of sleep medications and sleep disorders of study group were significantly lower than before treatment(all P ＜ 0.01);after treatment PSQI total scale score and all items scores of study group were significantly lower than the control group(all P ＜ 0.05).Conclusion Adjuvant treatment of brain electromagnetic had significant effects of improving sleep quality,relieving anxiety and somatization for neurological patients.

Coenzyme Q (CoQ),also known as ubiquinone,is a lipid-soluble quinone compound which exists in biological organis ms widely.The numbers of side chain isoprene of different sources of coenzyme Q are different.Coenzyme Q in humans and mammals are called coenzyme Q10 (CoQ10 ,Q10 ), in that the ubiquinone side chain of humans and mammals are mainly composed of 10 isoprene units.In the mitochondrial respiratory chain,it acts as a mobile electron transporter and is a cofactor of uncoup-ling proteins,which is an essential endogenous substance in the process of cell respiration and metabo-lis m.Moreover,CoQ possesses independent antiapoptosis feature,which regulates the mitochondrial permeability transition pore.Mitochondrion is an important organelle,which is the place for energy stor-age and supply,providing the energy for vital movement.There are various kinds of chemical toxicants in the hu man environ ment,and they can enter into the hu man body through drinking,feeding or breath-ing and then affect cell mitochondria to different degrees.Thus,it is important for preventive medicine to investigate intervention or reduction of the biological da mage of exogenous chemicals′effects on mito-chondria.In this paper,we reviewed the research progress of the role of coenzyme Q in xenobiotics in-duced mitochondrial da mage.

Acupuncture Points ; Acupuncture Therapy ; instrumentation ; methods ; Child ; Child, Preschool ; Enuresis ; physiopathology ; therapy ; Female ; Humans ; Male ; Treatment Outcome

ObjectiveThrough different disease period the serum β2-microglobulin (β2-MG),Retinal binding protein (RBP) and Cystatin C (Cys-C) joint test,to evaluate the clinical value of the combination detection of early diagnosis of acute kidney injury (AKI).MethodsOur choice in March 2011 to February 2012 in the same period and 88 patients with AKI physical examination in 63 cases,in the new HITACHI7600-020 automatic biochemistry analyzer and into test sample β2-MG,RBP and Cys-C content.ResultsThe patients with AKI of serum β2-MG,RBP and Cys-C compared with the control were significantly increased,the differences were significant ( P ＜ 0.05 or P ＜0.01 ).ConclusionSerum β2-MG,RBP and Cys-C are sensitive idicators in early diagnosis of AKI,three united detection help early diagnosis AKI,clinical doctors can provide reliable accurate valuable diagnostic basis for guidance.

Objective To investigate the influence of continuous infusion of low-dose dexmedetomidine (DEX) on the hemodynamic in elderly surgical patients during induction of combined spinal-epidural anesthesia (CSEA).Methods Fifty elderly lower limb surgical patients were randomly divded into DEX group and control group(25 cases each).After the cannulation of left radial artery,the non-invasive hemodynamic monitor was connected,and the hemodynamic index was continuously monitored,including systolic blood pressure (SBP),diastolic blood pressure(DBP),heart rate(HR);and respiratory index was monitored,including respiration rate(RR),pulse oxygen saturation( SpO2 ).Before CSEA,the patients in DEX group were administered DEX of loading dose(0.5 μg · kg-1),then continuously infused with DEX at 0.2 ～ 0.4μg · kg-1 · h-1 to keep Ramsay sedation score from 4point to 5point,and SpO2 ≥95％.Normal saline was administered with an equal volume in control group.The SBP,DBP,HR,RR,SpO2 were recorded immediately at the T0,T1,T2,T3,T4 and T5.Results All hemodyanmic and respiratory parameters in both groups were normal during induction.Compared with T2 in DEX group,differences of SBP and DBP between two groups were statistically significant,and the value significantly lower at T3 (P ＜ 0.05 ) ;compared T2 with T1 in control group,differences of SBP,DBP and HR among three groups were statistically significant,and the value was significantly higher at T2 ( P ＜ 0.05 ).Compared with T2,SBP,DBP,HR were significantly lower than T3,( P ＜0.05).And RR of T1,T2,T3,T4,T5 in DEX group was significanfly lower than T0,with statistical significance( P ＜0.05) ;the difference of RR among different time was not statistically significant in control group(P ＞ 0.05 ).Conclusion The continuous infusion of small-dosage DEX during CSEA in elderly lower limb surgical patients may have little impact on cardiac function index when achieved effective sedation and analgesia.

Tai Chi Chuanis a traditional Chinese method of regimen and health care, which has attracted wide attention from countries in the world. This article was aimed to analyze the current situation and hot spots about Tai Chi Chuan for future research. A total of 1349 articles were retrieved from Web of Science from 1981 to 2013. CiteSpace was used to map knowledge domain of 1349 articles in order to explore the current situation and hot spots aboutTai Chi Chuan internationally. The results showed that the research onTai Chi Chuan showed a rising trend. The main research regions were in the United States and China. The research fields were extended from medicine and sport science to psychology, engineering and computer science. The hot spots were focused on physical control, psychology and cardiovascular diseases. It was concluded thatTai Chi Chuan was a method benefit to both physical and mental health. The focus of future Tai Chi Chuan research was on basic theory, action mechanism and strict evidences.

Objective To investigate the effect of Pudilan combined with ribavirin in treatment of the hand-foot-mouth disease(HFMD). Methods 70 patients were randomly divided into treatment group ( Pudilan combined with ribavirin) and control group (ribavirin only). Results Compared with the control group,the cure rate and the effective rate in treatment group had statistically significant difference ( all P ＜ 0.05 ). Compared with the control group,the rash disappeared time and the fever subsiding time in treatment group were shorter obviously ( all P ＜0. 05 ). The both groups had no obvious side effect. Conclusion Pudilan combined with ribavirin in the treatment of HFMD had a good therapeutic effect and were a safe and effective method.

The conception of nutrition risk and malnutrition risk are not strictly differentiated in clinical.Nutri-tional risk was associated with a higher complications incidence,mortality and longer length of hospital stay.It′s nece-ssary to carry out nutrition risk screening to decide whether the need for nutritional intervention.This article introduces the clinical epidemiological characteristics of nutritional risk in children,nutrition risk score,nutritional risk screening, subjective global assessment,and screening tool for risk of impaired nutritional status and growth.It′s very important to apply a rapid and easy nutrition risk screening tools.Then,also discussions the relationship between nutritional risk screening and nutritional therapy,put forward on the strategies for assess and prevent malnutrition in children,and loo-king for the best way of nutritional support to ensure the body and cells metabolism,reduce the extent of tissue damage and promote the recovery of the disease.