1.CT Diagnosis of Pulmonary Sequestration
Journal of Practical Radiology 2001;17(5):351-353
Objective In order to improve diagnosis of the disease,CT appearances of pulmonary sequestration were studied.Methods 10 cases were proved by surgery and pathology.Lung inner type was in 9 and lung exterior type in 1.All cases were examined with plain CT scans and 5 of them were taken thin slice CT scan with contrast enhancement.Results 10 cases located in the posterior segment of right or left lower lobes,3 of them were cystic,3 were solid,4 were cystic and solid.The emphysema around the lesions were showed in 7 cases.Abnormal arterial supply could be seen in 7 cases.Conclusion CT not only can demonstrate lesions and changes of tissue surrounding lesions,but also can manifest abnormal supplying blood vessels well.CT plays important role to diagnose pulmonary sequestration.
2.Application and recent research progress of irinotecan in treatment of advanced colorectal cancer.
Chinese Journal of Oncology 2006;28(9):718-719
Agranulocytosis
;
chemically induced
;
Antineoplastic Agents, Phytogenic
;
administration & dosage
;
adverse effects
;
Antineoplastic Combined Chemotherapy Protocols
;
adverse effects
;
therapeutic use
;
Camptothecin
;
administration & dosage
;
adverse effects
;
analogs & derivatives
;
therapeutic use
;
Colorectal Neoplasms
;
drug therapy
;
pathology
;
Diarrhea
;
chemically induced
;
Drug Resistance, Neoplasm
;
Fluorouracil
;
adverse effects
;
therapeutic use
;
Humans
;
Leucovorin
;
adverse effects
;
therapeutic use
;
Neoplasm Staging
;
Survival Analysis
4.Angiotensin-converting enzyme inhibitor captopril attenuates ventilator-induced lung injury in rats
Journal of Third Military Medical University 2003;0(21):-
Objective To study the relationship between lung inflammation and lung angiotensin Ⅱ ( ANG Ⅱ) in ventilator-induced lung injury ( VILI) and assessed the efficiency of the angiotensin-converting enzyme inhibitor captopril to attenuate VILI in rats. Methods Totally 21 adult male Sprague-Dawley rats were randomly assigned into 3 groups,high-volume,0 positive end-expiratory pressure ( HVZP) group; captopril injection ( 100 mg/kg i. p. ) in 30 min before HVZP ventilation ( HVZP + CAP group) ; no ventilation group ( control) . The blood gas tensions and mean arterial pressure were measured after a polyethylene catheter was placed in one carotid artery and a plastic cannula was inserted into the trachea. The protein contents and contents of macrophage inflammatory protein-2 ( MIP-2) in bronchoalveolar lavage fluid ( BALF) and lung ANGⅡ were determined by ELISA. The changes of lung pathology were observed by HE staining. Results Mean arterial pressure was significantly lower in the HVZP + CAP group than in the HVZP group after 2 hour’s ventilation. Total protein levels were significantly higher in BALF recovered from HVZP-ventilated rats than from controls. BALF MIP-2 and lung ANG Ⅱ were significantly higher in the HVZP group than in the control and HVZP + CAP groups. Lung ANG Ⅱ level was correlated positively with BALF contents of total protein and MIP-2. Conclusion Captopril has the efficiency to attenuate VILI by reducing inflammatory cytokines. Our results suggest that VILI is partly mediated by the local angiotensin system.
5.Effects of Trillim tschonskii maxim on microvessels response and anti-oxidation enzyme in burned rats.
Chinese Journal of Applied Physiology 2011;27(4):483-494
Animals
;
Burns
;
drug therapy
;
metabolism
;
physiopathology
;
Drugs, Chinese Herbal
;
pharmacology
;
therapeutic use
;
Female
;
Male
;
Mesentery
;
blood supply
;
Microvessels
;
drug effects
;
physiopathology
;
Phytotherapy
;
Rats
;
Rats, Sprague-Dawley
;
Superoxide Dismutase
;
metabolism
;
Trillium
;
chemistry
8.Retraction:Discussion on quantum entanglement theory and acupuncture.
Chinese Acupuncture & Moxibustion 2019;39(3):e026-e026
The article "Discussion on quantum entanglement theory and acupuncture" (doi: 10.13703/j.0255-2930.2017.11.026, published in Zhongguo Zhen Jiu 2017,37(11):1233-1237) has some defects, and the author of the article proposes to withdraw the manuscript. According to the retraction provisions of our journal, it is considered that the author's application complies with the relevant provisions and our journal agrees to withdraw the draft.
9.Change of Urinary Leukotriene E_4 Level in Children with Respiratory Syncytial Virus Bronchiolitis and Its Clinical Significance
Ai-zhen, WANG ; Zhen-yu, ZHANG ; Luo-zhong, ZHAO
Journal of Applied Clinical Pediatrics 2006;0(16):-
Objective To explore the clinical significance of urinary leukotriene E4(LTE4) in children with respiratory syncytial virus(RSV) bronchiolitis.Methods Forty infants with bronchiolitis were enrolled for the identification of RSV-Ag from the nasopharyngeal secretions.Forty cases who were found to be positive of RSV were put into RSV bronchiolitis group.According to the severity of illness,the infants in RSV bronchiolitis group were separated into 2 subgroups:mild illness group (24 cases) and moderate illness group (16 cases).Thirty healthy children were chosen as healthy control group.Urine of the patients in RSV bronchiolitis group was collected in acute phase (on the 1st day) and recovery phase (on the 7th day after the admission).Urine of children in control group was collected .Enzyme-linked immunosorbent assay was used to assay the level of urinary LTE4.Results The levels of LTE4 in healthy control group (M,Q) were 1.28 pmol?mmol-1,1.72 pmol?mmol-1,while the levels of LTE4 in acute phase in RSV bronchiolitis group (M,Q were 30.52 pmol?mmol-1,23.56 pmol?mmol-1,and the levels of LTE4 in recovery phase in RSV bronchiolitis group (M,Q) were 3.98 pmol?mmol-1,3.43 pmol?mmol-1.Urinary LTE4 levels in acute phase in RSV bronchiolitis group were significantly higher than those in healthy control group (P
10.Current situation of the characters of kidney impairment induced by Chinese herbal medicine containing aristolochic acid
Wei ZHANG ; Wenzheng HUANG ; Zhong ZHEN
Chinese Journal of Tissue Engineering Research 2006;10(39):189-192
OBJECTIVE: To explain the current situation of the study on Chinese herb nephropathy (CHN), clarify the concept of CHN and investigate the pathogenesis, also suggest the measures for the prevention and treatment of CHN.DATA SOURCES: Articles about kidney impairment induced by Chinese herbal medicine containing aristolochic acid (AA) published in English between January 1994 and April 2006 were searched in Pubmed database by using the keywords of "kidney impairment induced by Chinese herbal medicine containing aristolochic acid (AA), nephropathy induced by aristolochic acid (AA), Chinese herb nephropathy (CHN)". Other articles were collected by the specific name of journals and title of papers by retrieving VIP database.STUDY SELECTION: The original articles were checked primarily, those about kidney impairment induced by Chinese herbal medicine containing AA were selected, those obviously irrelevant ones were excluded, and the full-texts of the involved articles were searched manually.DATA EXTRACTION: Totally 86 articles were collected, 20 of them were involved, and the other 66 repetitive studies or reviews were excluded:DATA SYNTHESIS: At present, kidney impairment induced by Chinese herbal medicine has not attracted enough attentions in Chinese, and effective monitoring system should be established. The diagnosis and pathogenesis of nephropathy induced by AA are still unclear, and the prevention is the main treatment. Therefore, we should realize its harmfulness, and reinforce its basic and clinical researches.CONCLUSION: The main damage in kidney caused by AA focuses on the renal tubulointerstitial matrix. Renal glomerulus is rarely involved in the toxic process. Clinical manifestations also reflect the impairment of renal tubules and interstitium such as interstitial fibrosis. A more effective diagnosis monitoring and screening system should be set up in order to mesh the patients at the early stage. A more stringent method for classification of the species in fourstamen stephania root family will be established to avoid confusion and error. More valid therapeutic channels should investigate for its remedy.