arotid artery atherosclerosis is closely associated with ischemic stroke.Carotid artery intimamedia thickness is an important indicator of carotid artery atherosclerosis.Magnesium is involved in the in vivo metabolism of a wide variety of processes.Studies have shown that magnesium can decrease carotid intimamedia thickness.This article reviews the relationship between magnesium levels and carotid artery atherosclerosis in different populations.

Objective: To develop the Chinese mood adjective check list (CMACL) and study the validation of this scale. Methods: The CMACL was filled by 1010 subjects aged 21.0 ? 7.4, 507 males and 464 females (39 lost gender information), which were randomly split into two samples after balancing the gender for exploratory factor analysis (EFA) and confirmatory factor analysis (CFA). 232 middle school students divided into five groups according to their grades were engaged in the test-retest study at the first to fourth and sixth weeks. 34 volunteers finished the CMACL and self-rating depression scale (SDS) and 30 college students joined the validation study to test the correlation between the CMACL and state trait anxiety inventory. Results: A four-factor model was found by EFA and confirmed by CFA, which has the following dimensions: Fidget(F)?Happy and excited(HE), Pain and sad(PS),Angry and hate(AH). 30 items were also left in the CMACL after the modification(GFI=0.902,AGFI=0.883,NFI=0.884,TLI=0.931,CFI=0.937,RMSEA=0.046). Reliabilities of the four factors are higher than 0.80. Validation studies showed: (1) SDS total score is significantly positive-correlated with F (P

Objective: to develop the peptic ulcer (PU) symptoms self rating scale (PUSRS) and study the validation of this scale. Methods: The PUSRS was filled by 151 PU patients, 118 males and 30 females (3 lost gender information, aged 38.61?14.99), which were recruited from 18 gastroenterology departments. 30 PU patients were engaged in the test-retest study. 40 PU patients and 30 gastritis patients joined the discriminate validation study. Results: Two factors, pain factor (PF) and dyspepsia factor(DF), were found by exploratory factor analysis. Reliabilities of the two factors are 0.786 (PF) and 0.753(DF). Validation studies showed that PU patients have significantly higher PUSRS total score (P

Disc polyacrylamide gel clectrophorsis was performed to detect water soluble proteins of the bile－cysts of bear, pig, cow and sheep. The bands of electrophorsis were analysed by means of gel clecrophoresis scan. The results showed that different bile－cysts have different bands.Thus, this method can be used to identify the bile－cyst of bear.

Objective:To investigate the adjuvant effect of initial periodontal therapy by observing the eradiation rate of gastric helicobacter pylori( Hp) in the patients with gastric ulcer treated by the therapy. Methods:Totally 88 patients with stomach ulcer and chronic periodontitis were enrolled and randomly divided into two groups. The control group was treated by triple therapy,the experimental group was treated by initial periodontal therapy additionally with the treatment course of one month. The changes of Hp in stomach and periodontium were observed and the eradiation rate of Hp was compared between the two groups respectively after 1-, 3-, 6-and 12-month treatment. Results:After 3, 6 and 12 months, the eradiation rate in the experimental group was significantly higher than that in the other group (P < 0. 05). Conclusion: Initial periodontal therapy combined with triple therapy can obviously improve the eradication rate of gastric Hp in the patients with gastric ulcer and chronic periodontitis.

Adolescent ; Anti-Arrhythmia Agents ; therapeutic use ; Child ; Child, Preschool ; Echocardiography, Doppler, Color ; Electrocardiography ; Exercise Therapy ; Female ; Follow-Up Studies ; Humans ; Male ; Retrospective Studies ; Treatment Outcome ; Ventricular Premature Complexes ; diagnosis ; etiology ; therapy

Objective To score the fall risk of hospitalized patients with neurologic disease using fall risk scale and observe the changes of fall risk score after this fall risk scale was used. Methods The fall risk scale in hospitalized patients in neurology department was designed. The fall risk of hospitalized patients in neurology department from January 2005 to December 2007 were assessed. Moreover, safety nursing mea-sures were brought into practice to prevent from falling down. The fall risk of hospitalized patients in neurolo-gy department from January 2002 to December 2004 were assessed too. Results Target patients enhanced the sense of preventing from falling down after the fall risk scale was used, and the incidence of falls in pa-tients was significantly decreased. Conclusions To assess the fall risk of hospitalized patients in neurology department and implement safety nursing measures among the target patients may be effective in preventing the patients from falling down.

Objective:To discuss the clinical assessment value of comprehensive echocardiographic parameters in detecting the left ventricular diastolic function in patients with hypertension. Methods: 60 hypertensive patients (30 cases without left ventricular hypertrophy (non-LVH), 30 cases with left ventricular hypertrophy(LVH) were divided into hypertension group, and 60 healthy subjects were in control group. All of the subjects were underwent M type, color ultrasound and tissue Doppler imaging (TDI). And to compare their comprehensive echocardiographic parameters.Results: Compared with the healthy control group, the IVSd, LVPWd, LVMI, LAD and LVD of hypertension group were significantly enlargement; the s', e', E peak and LVEDP of hypertension group also significantly increased, while a' and A peak were significantly reduced; compared with non-LVH, e', E peak and LVEDP of LVH group were significantly increased, and a' and A peak were significantly reduced, and these differences were statistically significant (t=-4.39,t=-4.39,t=5.47,t=-8.02, t=6.20,t=18.95, t=16.12;P<0.01).Conclusion: The comprehensive echocardiographic parameters can evaluate the extent of damage for left ventricular diastolic function of patients with hypertension, and they can be as the assessment standard of left ventricular hypertrophy. In clinical practice, TDI can be used as a new means in the evaluation of ventricular diastolic function.

Child ; Child, Preschool ; Enterovirus ; isolation & purification ; Enterovirus A, Human ; isolation & purification ; Female ; Fluorescence ; Hand, Foot and Mouth Disease ; virology ; Humans ; Infant ; Male ; Polymerase Chain Reaction ; methods ; RNA, Viral ; analysis

Isocitrate lyase (ICL) which plays a pivotal role in the glyoxylate cycle of mycobacterium tuberculosis(MTB) could be a potential target against mycobacterium tuberculosis.Deoxyribozyme(DRz) is a small single-strand,enzymatic DNA molecule.Assistant by sketch of secondary structure,appropriate and not appropriate target sequences of MTB ICL mRNA were predicted.Two DRzs were designed targeting above sequences respectively.To affirm feasibility of this kind of prediction,in vitro cleavage of MTB ICL mRNA segment by DRz-ICLcf and DRz-ICLcj were performed.The results showed that sketch of secondary structure could indeed predict potential target of DRz.This research will provide basis for developing DRz as a novel antimicrobial agent against MTB.