1. A trial with 4 pairs of piglets (litter mates) fed a synthetic diet ba- sed on 25% purified soya protein concentrate, Danpro-A, 25% soluble ma ize starch, 14.6% glucose, 12.0% lactose, 5% soya oil and 5% lard without (diet A) or with a supplement of 0.2% DL-methionine (diet B) has been carried out. The piglets were kept individually in metabolic crates during the whole experimental time from 7 to 56 days of age. By means of bottles with lambteats they could suck their liquid diet at any time. Five to six consecutive balances were carried out with each piglet in order to measure the digestibility, metabolizability, nitrogen balances and energy metabolism (Indirect calorimetry, open-air respiration chambers).2. No significant differences were found concerning feed intake or live weight gain between the piglets on diet A or B.3. The digestibility of dry matter, organic matters, nitrogen and energy together with the metabolizability (ME/GE) were significantly lower for piglets below 4 weeks of age than above that age where a high digestibility and metabolizability of about 95% were obtained with no significant difference between diet A and B.4. The intake of nitrogen was kept relatively low (17.4% crude protein in the diets) in order to measure any differences in the nitrogen metabolism which might occur by adding methionine. With the low nitrogen intake the nitrogen retention was a linear function of digested nitrogen. No significant difference was found between diet A and B, The pooled data gave a regression of RN = -0.524 + 0.829 DN5. Energy retention in relation to total ME gave a regression coefficient of 0.436 with no significant difference between diet A and B.6. The proportion between energy gain in fat and protein was fairly constant about 1.4 during the experimental time with no significant difference between diet A and B.7. The daily maintenance requirement was found to be 575KgJ/kg0.75 with no significant difference between the diets.8. The net availability of ME for growth, Kg, was high 0.767 but the accuracy of the estimate was low with CV=14.6%.9. The hige digestibility of nitrogen, the high utilization of digested nitrogen and the high value of Kg indicate that a soya protein concentrate as Danpro-A can be used as the only protein source in a sowmilk substitute. Adding 0.2% DL-methionine to the diet has not improved the results.

Survivin is one of inhibitors of apoptosis protein family members. It is highly expressed in lung cancer. Survivin can inhibit apoptosis. Apoptosis is closely related with development and prognosis in lung cancer. Survivin and apoptosis might become breakthrough point in treatment of lung cancer.

In recent years, researchers have made some breakthroughs on human embryonic stem cells, in particular, on reprogramming differentiated cell (such as human skin fibroblast) into human embryonic stem cell. Induced pluripotent stem cells could be generated from human skin fibroblasts by inducting into four transcription factors known as OCT3/4, SOX2, C-MYC and KLF4. This approach enables better understanding the pathogenesis of diseases from the perspective of genetic component and promising in the treatment of related diseases. This article introduces the latest advancement of those researches.

Objective To compare the effect and safety of totally transumbilical single -port laparoscopic herniorrhaphy and traditional surgery in treatment with pediatric indirect inguinal hernia.Methods 100 children with indirect inguinal hernia were divided into control group(n =50)and observation group(n =50).The control group was given to traditional surgery.The observation group was given to totally transumbilical single -port laparoscopic herniorrhaphy.The operation related index,postoperative complications and hernia recurrence rate were compared between the two groups.Results The intraoperatve bleeding,incision length,operation time and hospital stays of the observation group respectively were (18.1 ±5.9)mL,(1.3 ±0.3)cm,(27.4 ±7.9)min and (4.5 ±1.2)d,those of the control group respectively were (38.7 ±8.1)mL,(2.2 ±0.4)cm,(46.7 ±9.2)min and (7.4 ±1.3)d,the difference was statistically significant (t =3.439,3.811,2.872,2.878,P =0.026,0.019,0.045,0.049).The postoperative complications rate of observation the group and the control group were respectively 8.0%(4 /50)and 24.0%(12 /50),the difference was statistically significant(χ2 =4.762,P =0.029).Postoperative follow -up of 1 year,the hernia recurrence rate of the observation group and the control group respectively was 0(0 /50)and 12%(6 /50),the difference was statistically significant (χ2 =6.383,P =0.012).Conclusion Using totally transumbili-cal single -port laparoscopic herniorrhaphy treat with pediatric indirect inguinal hernia is safe and effective.It is ben-eficial to prevent recurrence,and is worth clinical promotion.

Vitamin D binding protein ( VDBP) is a multi-functional plasma globulin which binds to the vitamin D ( VD) in the circulation system and transporting the latter to various effective organs to exert its biological functions .Studies have found that VD and its carrier VDBP are associated with the risk of various cancers such as breast cancer , prostate cancer , and colorectal cancer however , lacking sufficient epidemiological evidences so far .Furthermore , it is still controversial regarding how VD controls and affects cancer progression.In addition, studies have also demonstrated that VDBP derived macrophage-activating factor (GcMAF) is a potent lymphokine in cancer treatment .Nonetheless, the relationship between VDBP and cancer including the VDBP polymorphism, VDBP plasma concentration are still unclear; more studies are needed to further uncover its role in cancer development and progression , thus providing new evidences for cancer diagnosis, treatment, and prognosis.

OBJECTIVE: To introduce the methods of drug purchase management and drug use monitoring in our hospital,and to provide reference for drug management in hospitals.METHODS: Sunshine Project of New Drug Purchase and scientific selection methods for contract drugs were carried out in order to control the quality of drugs and monitor the whole process of new drugs.RESULTS: 82 kinds of new drugs were purchased in our hospital since 2005 and 1 500 kings of drugs were voted by randomly selected experts to apply in the clinic.The consumption sum of drugs in our hospital were controlled within 500 million yuan,and the drug use was basically rational.CONCLUSIONS: Methods for new drugs purchase and use in our hospital can promote rational use of drugs in the clinic.

Objective:To examine the correlation between the self-worth and mental health of middle school students .Methods:The Scale of Self-worth for Young Students and the SCL-90 were admemestered to a sample of 699 middle school students.Results:Analysis showed significant negative correlation between self-worth and the SCL-90 and mental health of middle school students,the SCL-90 scores of students with high self-worth were significantly different from that of students with low self-worth.Conclusion:The higher the self-worth of middle school students is ,the better their mental health is.

Esophageal cancer is one of the most common malignant tumors in the digestive tract. Its morbidity and mortality rates are high. Local advanced esophageal cancer relapses easily after operation and has a poor prognosis. Operation-based comprehensive treatment plays an important role in reducing the recurrence rate and increasing the survival rate. Radiotherapy is an important part of comprehensive treatment. From conventional radiotherapy two dimeusional conformal (2DCRT) to three dimensional conformal ra-diotherapy (3DCRT), intensity modulated radiation therapy (IMRT), image guide radiation therapy (IGRT), and volumetric modulated arc therapy (VMAT), radiotherapy technologies have experienced significant development. This development optimized the dose distri-bution and improved the accuracy of radiation. It has also provided a new understanding of the methods of radiotherapy, such as pre-operation radiotherapy, post-operation radiotherapy, and radiotherapy combined with chemotherapy. The progress of radiotherapy re-search on esophageal cancer is reviewed in this paper.

Objectives:To investigate the efficacy of STI/HIV preventive intervention on prostitutes and to discuss the ethical issues.Method:Anonymous questionnaire survey was used to collect the KAB data before and after health education. The data were analysed by using SPSS10.0 software. Results:140 prostitutes received health education and 87 prostitutes were evaluated after intervention.Both the condom knowledge and the condom use during sex increased significantly after health education(P

0 05) There was significant difference of relieve of abdominal pain in every group before treatment,and in 3 days,1 week after treatment (P0 05) The main adverse drug reactions were nause,vomiting,anorexia and mild diarrhoea,and special taste in a few cases Total incidence of adverse reaction was 28% in group A,4 3% in group B and 25% in group C There were significant differences among three groups(P