1.Comparison of percutaneous versus open pedicle screw fixation for thoracolumbar fractures:a Meta analysis
Chongqing Medicine 2015;(6):810-812
Objective To compare the feasibility and efficacy of PPSF with OPSF for thoracolumbar fractures.Methods We searched the PUBMED,OVID and Cochrane CENTRAL databases through Jan 2014.All of the clinical trials included were extrac-ted and evaluated by two reviewers independently.Data were analyzed using RevMan 5.2.6 software by the Cochrane Collabora-tion.Results Seven studies including 353 patients met the inclusion criteria.The Meta analysis found there were significant differ-ences between the two procedures in intraoperation blood loss (RR = 1.89,95%CI :1.55 - 2.29,P < 0.05)and operation time (RR=1.21,95%CI :1.12-1.30,P <0.05).For the correction of sagittal Cobb′s angle and the anterior vertebral body height,a-nalysis did not find any significant difference between the PPSF and OPSF(P >0.05).Conclusion Both PPSF and OPSF are safe and efficacious internal fixation methods for treating thoracolumbar fractures,while,PPSF may cause less blood loss and cost less time.
2.Current understanding of ABCA1 in lipid accumulation
Basic & Clinical Medicine 2017;37(6):869-873
ATP-binding cassette transporter A1 (ABCA1) is an membrane protein,using ATP for transferring substances,modulated by liver X receptors(LXRs), retinoic X receptors(RXRs), sterol regulatory element binding proteins(SREBPs), microRNAs and other upstream modulators.ABCA1 plays an important role in multiple pathways related to lipid accumulation.Upregulating ABCA1 expression may slow-down lipid accumulation, thus offers a promising strategy for metabolic diseases.
3.FORENSIC PATHOLOGIC DIAGNOSIS OF SUDDEN DEATH CAUSED BY THE VIRAL MYOCARDITIS
Chinese Journal of Forensic Medicine 1986;0(02):-
This paper reports the forensic pathological diagnosis of 3 cases of sudden death caused by the viral myocarditis. The mechanism of sudden death was discussed.
4.Elementary Introduction on Practice Teaching in Clinical Microbiological Analysis
Chinese Journal of Medical Education Research 2003;0(02):-
To attach importance to practice teaching in clinical microbiological analysis,the overall planning,research-on-research and systematic training must be carried out.
5.The Analysis of the Factors Affecting the Employment of Grade 2006 Undergraduates in a Medical University
Chinese Journal of Medical Education Research 2003;0(02):-
Goal To research the major factors affecting medical undergraduates' employment.Method In combination with quantity and quality,we reasonably analyzed the factors affecting the employment of Grade 2006 undergraduates in a Medical University in Chongqing.Result The major factors consist of the inadequate knowledge、the increased condition admission、hidden rule and the unreasonable objects.Conclusion Medical universities should try their best to adapt to the development of the society and medical students should try to become the useful talents.
6.Pathologic diagnosis and classification of vasculitis.
Chinese Journal of Pathology 2006;35(3):179-182
Churg-Strauss Syndrome
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pathology
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Diagnosis, Differential
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Giant Cell Arteritis
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pathology
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Granulomatosis with Polyangiitis
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pathology
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Humans
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Mucocutaneous Lymph Node Syndrome
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pathology
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Polyarteritis Nodosa
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pathology
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Purpura, Schoenlein-Henoch
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pathology
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Takayasu Arteritis
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pathology
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Thromboangiitis Obliterans
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pathology
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Vasculitis
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classification
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pathology
7.Myxofibrosarcoma and low-grade fibromyxoid sarcoma.
Chinese Journal of Pathology 2007;36(4):271-273
Cyclin E
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metabolism
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Dermatofibrosarcoma
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pathology
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Diagnosis, Differential
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Fibrosarcoma
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classification
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metabolism
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pathology
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Humans
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Ki-67 Antigen
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metabolism
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Liposarcoma
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pathology
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Myxoma
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pathology
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Myxosarcoma
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metabolism
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pathology
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Proliferating Cell Nuclear Antigen
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metabolism
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Proto-Oncogene Proteins p21(ras)
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metabolism
8.Preliminary development of warning scale of suicide ideation of inpatients with somatic disease
Yunlong DENG ; Yu ZHONG ; Chen PAN
Chinese Journal of Behavioral Medicine and Brain Science 2014;23(5):469-471
Objective To form a concise and useful warning scale of suicide ideation of inpatients with somatic disease.Methods 2 677 inpatients who were more than 15 years old were randomly selected in a comprehensive hospital during the period of 2010.11-2013.02.Self-rating Depression Scale (SDS),Self-rating Anxiety Scale(SAS) and self-designed questionnaires which included general information,suicide risk factors and somatic disease were applied.Chi square test,partial correlation analysis,t test,correlation analysis and ROC curve analysis were used for statistical analysis.Results 1.The warning scale of suicide ideation which contained 18 items was formed.2.The Cronbach's Alpha reliability of the warning scale was 0.84 and its split-half reliability was 0.60.Criterion-related validity studies showed that the scores of the 18 items were positive correlated with SDS and SAS(r SDS =0.50,r SAS =0.54,P<0.01).This scale also had good structure validity.3.The ROC curve concluded that the area under curve was 0.83,the sensitivity was 68.40% and the specificity was 79.20%.Positive and negative predictive values were 21.22% and 96.83% respectively.Conclusion The reliability and validity of the warning scale entirely accorded with psychometric demands.It also has good specificity and negative predictive value,so it is suitable for clinical promotion.
9.Expression and specific cell response of autoantigen Dsg3 in pemphigus vulgaris
Anmei DENG ; Renqian ZHONG ; Sunxiao CHEN
Chinese Journal of Immunology 1985;0(03):-
Objective:In view of analysis of role of autoantigen Dsg3 in specific T cell response to understand the molecular mechanism of autoimmune diseases.Methods:Based on the sequence analysis of autoantigen Dsg3,the five fractions cDNAs of Dsg3 were cloned and Dsg3-GST fusion proteins induced by IPTG in E.coli.JM109 were purified,then mixed-cultured with T cell from PV patients.The T cell proliferation response were analyzed by MTT.Results:Dsg3 E1,E2 and E4,E5 stimulated T cell from PV patients,not controls.Conclusion:Dsg3 E1,E2 and E4,E5 contained the epitopes relevant to T-B cell interaction,which play an important role in the pathogenesis of pemphigus vulgaris.
10.Transrectal ultrasound guided prostatic nerve blockade for pain control during transrectal prostate biopsy
Liuping YANG ; Hong ZHONG ; Junhong DENG
Chinese Journal of Ultrasonography 1993;0(01):-
Objective To evaluate the safety and efficacy of transrectal ultrasound guided prostatic nerve blockade for pain control during transrectal prostate biopsy.Methods Seventy-three patients requiring systematic 13 cores biopsy of the prostate were randomized into two groups.Group A(37 cases) received an injection of 5 ml 1% lidocaine into the prostatic neurovascular bundles on each side at the base of the prostate under ultrasound guidance,and group B(36 cases) received 5 ml saline ( 0.9% sodium chloride) at the same way.Pain during biopsy was assessed using a 10-point linear visual analog pain scale immediately after this procedure.Results The mean pain scores during transrectal prostate biopsy were significantly lower in group A than that in group B( 1.1? 0.6 vs 5.9? 3.1,t= 4.81,P