Objective To explore the high-risk prognostic factors of patients with cervical cancer Methods To collect the clinical datas and follow-up visit results of patients, 365 cases of cervical cancer were retrospectively analyzed. To use Kaplan-Meier methods to calculate survival rate and use the Log-rank test to compare the significant difference between different survival curves. Based on the univarite survival analysis, COX proportional hazards regression model was adopted to analyze the risk prognostic factors.Results The 5-year, 10-year, 15-year and 20-year survival rates were 88 %, 83 %, 81% and 80%,respectively. In univariate survival analysis, there was significant differents between the survival curves of age and clinical stage (x2 = 19.738, P ＜0.01 and x2 = 36.672, P ＜0.01). And the survival rate of the higher age group was higher than the lower age group, the group of lower clinical stage was higher or equal to the group of higher clinical stage. In the COX regressive analysis, clinical stage and age were relevant to the prognosis of cervical cancer (P ＜0.01). Conclusion Age and clinical stage are prognostic factors of cervical cancer. Early diagnosis and treatment is still the main means to lower the rate of death resulted from the cervical cancer.