Acute leukemia marks the main type of non-solid cancer in children.Studies have proved that long non-coding RNA plays important roles in the pathogenesis of hematological malignancies and can be applied as a biomarker for diagnosis, prognosis and efficacy monitoring of leukemia patients.This article briefly reviews the roles of long non-coding RNA in the tumorigenesis and progression of childhood acute leukemia.

Adult ; Aged ; Aged, 80 and over ; Carrier Proteins ; metabolism ; Female ; Humans ; Inflammasomes ; metabolism ; Male ; Middle Aged ; Multiple Myeloma ; metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein