Urinary system often requires the restoration and reconstruction due to the impairments resulting from the congenital abnormality or acquired damage. Previously, some of autologous tissues are used as the substitutes of the restoration, but they are unsatisfactory regarding the complicated sampling, limited resources and many complications, as well as the inefficient structure and function of original tissues and organs. With the development of tissue engineering techniques, the tissue-engineered scaffold materials have provides a novel method for the restoration and reconstruction of urinary system. According to the sources, the tissue- engineered scaffold materials can be divided into artificially synthesized scaffolds, native scaffolds and extracellular matrix materials. Native scaffold materials carry good biocompatibility and low antigenicity, but their sources are little. Artificially synthesized scaffold materials are excellent in the physico-mechanical property, but some of them such as polylactic acid are absent to the specific information recognized by the cells, thus losing the cellular affinity. In contrast, extracellular matrix materials are better in the biocompatibility for the local urinary tissues. However, they are observed for only a short term, further researches needs to focus on the side effect or adverse reaction in vivo. In this study, three kinds of tissue-engineered scaffold materials have been introduced and their application characteristics in the restoration and reconstruction of urinary system are also analyzed, as well as their application prospect.

Recently, heme oxygenase-1 (HO-1) has been emphasized in the area of intensive care unit (ICU) and other domains. HO-1 can catalyze the decomposition of heine and the products of its enzymatic activity, including carbon monoxide, biliverdin, and bilirubin and ferritin can play a significant cytoprotec-tive role in antagonizing inflammation, protecting cells from oxidative injury and cellular stresses. In the re-search of severe acute pancreatitis (SAP), researchers have realized that it is of great importance to antago-nize the overflow of cytokines in order to improve the therapeutic effect of SAP. In this article, we give a re-view of the research progress of HO-1 and its relationship with SAP.

Gallbladder cancer is the most common malignancy of biliary tract with a very poor prognosis. The therapeutic strategy of gallbladder cancer has been improved in some aspects. Identifying the accurate stage is the basis of surgical treatment. Radical resection is the only choice of treatment which provides patients long survival. For most patients in T1a stage, simple cholecystectomy is adequate, but dissection of hepatoduodenal ligament should be added when the lesions located in neck and duct of gallbladder. Patients in T1b stage often need radical cholecystectomy. Radical cholecystectomy with Ⅳb and Ⅴ segmentectomy and lymphadenectomy of N2 nodes should be performed to patients in T2 stage. Extended right lobe resection can improve the prognosis of selected T3 and T4 patients.The effect of chemotherapy for gallbladder cancer remains unsatisfactory, and current chemotherapeutic regimens were based on 5-FU, gemcitabine or S-1. The effect of a new chemotherapeutic sensitization scheme with continuous infusion of somatostatin,epirubicin 5-FU/CF and cisplatin is under research, and the preliminary results are promising. Radiation shows some benefits to patients with gallbladder cancer, but its effects are still uncertain.

Purpose:To evaluate the relationship between po stoperative survival rate and three stage systems (Nevin,AJCC,JSBS) of gallbladd er carcinoma. Methods:From October 1988 to December 1998 a total of 30 patien ts with gallbladder carcinoma underwent radical resection in the Xinhua Hospital . All patients were classified by 3 different methods of staging.The 1-year,3- year ,5-year postoperative survival rates were evaluated according to the stage . Results:All patients with stage Ⅰ were alive. There were less cases in Nevin’s stageⅡ,Ⅲ. The 3-year,5-year survival rates in patients wit h Nevin’s stage Ⅱ,Ⅲ were better than the other two classifications. The 5-ye ar survival rates in patients with Nevin’s stage Ⅲ were better than those with Nevin’s stage Ⅳ. The 3-year,5-year survival rates in patients with Nevin’s stage Ⅳ/Ⅴ were significantly better than the other two classifications (P

BACKGROUND:Vascular grafts made of expanded polytetrafluoroethylene have been shown to have highly hydrophobic surface characterized by resistance to water penetration and biological durability. OBJECTIVE:To investigate the effects of vascular grafts made of expanded polytetrafluoroethylene for repair of peripheral arterial injuries. METHODS:Thirty-eight patients with peripheral arterial injuries, consisting of 30 males and 8 females, aged 17-61 years, were included in this study. After conventional fluid infusion, anti-shock treatment, anti-inflammation, and debridement, they received implantation of vascular grafts made of expanded polytetrafluoroethylene. A 12-month folow-up observation was performed to investigate the recovery of affected limbs and vascular patency in patients. RESULTS AND CONCLUSION:After implantation of vascular grafts made of expanded polytetrafluoroethylene, al vessels were unblocked and no cases died or had limbs amputated. Blood supply of al affected limbs recovered to normal and there was no vascular anastomotic infection. Imaging results showed that vascular patency rate was 100%. Ultrasound examination results showed that at the end of the folow-up period, the inner wal of the vascular grafts was smooth, obvious mural thrombus or anastomotic stenosis did not occur in any case, vascular patency rate was 92% (35/38), and no adverse reactions related to artificial vessels were observed. These findings suggest that vascular grafts made of expanded polytetrafluoroethylene for repair of peripheral arterial injuries exhibit striking surface anticoagulant property and long-term patency.

One case of secondary bleeding repeatedly after tonsillectomy. Secondary bleeding after tonsillectomy seldom happen to us. When the event occurs medical staff has to take effect way to control the bleeding immediately. Accumulated quantity of bleeding must be controlled to the lowest point as soon as possible. Other wise the bleeding may lead to death. This point should be considered by medical staff.
Humans ; Postoperative Hemorrhage ; etiology ; Tonsillectomy ; adverse effects

Objective: To prepare a functional chitosan thermosensitive hydrogel for minocycline-HCl gelatin microspheres and observe its effects on repairing experimental rats gingivitis. Methods: Minocycline-HCl gelatin microspheres were prepared by using gelatin as core material and emulsion crosslinking method, then the latter was incorporated into the chitosan thermosensitive hydrogel. Established an experimental gingivitis model in SD rats and to observe the effect of hydrogel on gingivitis. Results: Microspheres thermosensitive hydrogel had obviously sustained effects on gingivitis. Results showed that GI,PD in experiment group were significantly improved. Conclusion: The chitosan thermosensitive hydrogel loading of minocycline-HCl gelatin microspheres have antiphlogistic effects on experimental rats gingivitis.

Endoscopic ultrasound was initially introduced in 1980s as a diagnostic modality combining echoendoscopes with radial scanning, which permitted reconstruction of cross-sectional images similar to computed tomography. Many studies showed that endogastric ultrasonography is more accurate than endoscopy or CT in evaluating the depth of invasion ( T category) and the involvement of lymph nodes (N category) in patients with gastric carcinoma. In addition to being very useful in tissue acquisition for diagnostic purposes, the principles behind endoscopic ultrasound-guided fine needle aspiration ( FNA) paved the way for the development of therapeutic endoscopic ultrasound, which improve the prognosis of patients with gastric cancer.

Objective:To study TGC on tumor apopotosis and to apply the experimenting basis of TGC's developing and utilizing.Methods:The flow cytometer(FCM) was used for determination apoptosis.The protein expression of Bcl-2 and the mRNA expression of c-myc were evaluated by immunohistochemistry and in situ hybridization.Apoptosis small body were observed by EU.Results:The TGC group appear the Ap apex,the number of cell of G0-G1 period reduce obviously,the cells of S period increase obviously.Bcl-2 and the c-myc mRNA expression levels were decreased in TGC group.The structure of inner membrane was intacted with EU.Chromatin gathered side of cell,the nucleus turns into the nucleus band and nucleus project,there were many cells of the apoptosis and meniscus or the garland shape(the apoptosis corpuscle formatiol) in TGC group.Conclusion:The total glucosides of radix paeoniae induces the tumor cell apoptosising,its mechanism maybe closely related with adjusting expression levels of the Bcl-2 and the c-myc mRNA.

Objective To survey the Keshan disease conditions and its trend in the historical serious illness areas of the disease in Arong Banner,and to provide epidemiological evidence for scientific prevention and control of Keshan disease.Methods According to the requirements of National Keshan Disease Surveillance Program,two villages in 2 townships of Arong Banner were selected as monitoring sites in 2012,population in monitoring sites was conducted clinical examination and electrocardiogram (ECG) tracings;suspected cases of Keshan disease were conducted chest X ray and ultrasound heartbeat graph examination.At the same time,residents' income and staple food structure were investigated.Results The abnormal rate of ECG was 7.92％ (66/833).The detection rate of cardiac enlargement was 20.00％ (9/45) by chest X ray,in which a slight increase was 8.89％ (4/45),moderate increase was 4.44％ (2/45) and severe increase was 6.67％ (3/45).The detection rate of Keshan disease patients was 132.05/10 000 (11/833),including latent Keshan disease [72.03/10 000 (6/833)] and chronic Keshan disease [60.02/10 000 (5/833)].In the ECG abnormal changes of Keshan disease cases,ST-T change and right bundle branch block were common,accounting for 100.00％ (11/11) and 63.64％ (7/11),respectively;frequent ventricular premature contraction was 2 cases,accounting for 18.18％ (2/11),degree I ° atrioventricular block and complete left bundle branch block was both i case,accounting for 9.09％ (1/11).Annual per capita income in Arong Banner was 8 100 yuan;dweller staple food was rice,flour and other grain crops,rice accounted for 70％-80％,flour 15％-25％ and purchased non-local grain accounted for 95％.Conclusions Keshan disease has been under control at a lower level in Arong Banner,but new latent and chronic Keshan disease occur slowly,gradually and gradually accumulated;life quality and dietary structure have influence on the incidence.In the future,we should pay more attention to Keshan disease and do a good job on prevention and control of Keshan disease.