The MDA contents of platelet, plasma and lung tissue in rat endotoxemia were measured by TBA fluorescent method. It was showed that the lipid peroxidation of platelet and plasma was significantly increased, but there was no notable change of the lung tissue.

OBJECTIVE: To investigate the use of ?-receptor blockers,angiotensin converting enzyme inhibitors,aspirin and statins in acute myocardial infarction patients. METHODS: The general information of 119 cases of established acute myocardial infarction in 4 hospitals in Jiangbei district of Chongqing between 1999 to 2004 were analyzed retrospectively. RESULTS: The suitable use rates of ?-receptor blocker and angiotensin converting enzyme inhibitor are 79.0% and 85.7%, respectively, while their actual rates were 35.3% and 43.7%,respectively. Therefore among the suitable patients,55.3% of them did not receive the treatment with ?-receptor blockers and 49.0% did not take angiotensin converting enzyme inhibitors properly. The use rate of aspirin was high to 84.9%. The statins was not used until 2002 and its use rate was 15.1%. CONCLUSION: There exists significant gap between the practice and the requirement in“diagnositic and therapeutic guide for acute myocardial infarction” in the use of these drugs, except the aspirin. However, this situation is being changed.

Objective:To analyze and compare the dose monitoring and control systems of two types of medical linear accelerator systematically from the view of mechanical and electrical engineering, and establish the method of the quality assurance of the dosimetry system and the solution in the routine maintenance.Methods: To systematically compare and analyze the system of dose monitoring and control for two types of linear accelerators (Precise Elekta and C-series of Varian Medical Systems) from twofold aspects that included machine physics and electric engineering of medical linear accelerators.Results:The monitoring system that took ionization chamber as center was established between connotation of machine physics and concrete realization of electromechanical engineering, and explained the difference and similarity between open type and sealed type of ionization chamber, and the theory that Precise series needn't be serviced by PFN.Conclusion: Based on the analysis of ionization chambers structure of medical linear accelerators on the principle of quality assurance system, proposed dosimetric testing and adjustment method, and provide reference for the establishment of quality assurance system and technical procedures of the maintenance engineering.

The sonographie diagnosis of suhcutaneoyus nodules caused by lupg flukes in ten cases from the mountainous area of Xiangxi was reported.According to their ultrasonographic features,these nodules could be divided into three types:the substantial(one case),anechoic(two cases),and mixed type(seven cases).The sonographic characteristics,the pathotogic stages and the cytology of the subcutaneous nodules caused by lung fluke these cases were discussed.

Objective To observe the clinical efficacy of electrothermal needle apparatus in treating mild hip osteoarthritis.Method Ninety patients were divided into a control group and a treatment group by using the random number table, 45 cases in each group. The treatment group was intervened byelectrothermal needleapparatus; the control group was treated with ordinary electroacupuncture plus TDP radiation. After 15-day treatment, the therapeutic efficacies of the two groups were evaluated by using Visual Analogue Scale (VAS) and Japanese Orthopaedic Association (JOA) scores.Result The VAS and JOA scores were improved inthe two groups after the treatment (P<0.05), and the improvements in the treatment group were more significant than those in the control group after the 15-day treatment (P<0.05).Conclusion Electrothermal needle apparatus can produce a significant therapeutic efficacy in treating mild hip osteoarthritis.

With the increasingly deepening research on the molecular regulatory mechanisms during the development and progres-sion of advanced renal cell carcinoma, the targeted therapy directed on the key proteinase/protein in the molecular signaling pathways significantly improves the management outcomes. However, the occurring resistance during therapy with targeted agents leads to de-creasing effects. The mechanisms of action, resistance, and countermeasures of targeted therapy in advanced renal cell carcinoma are simply reviewed.

Objective To assess the modified two-window ilioinguinal approaches used for the open reduction and internal fixation of anterior wall/column fractures of acetabulum.Methods From March 2011 to March 2012,we treated 15 patients with anterior acetabular fractures by open reduction and internal fixation.They were 13 males and 2 females,18 to 53 years of age (mean,36.8 years).According to Judet & Letournel classification,we had 6 anterior column fractures,3 transverse plus posterior wall fractures 6 double column fractures.The anterior wall/column fractures were reduced and fixated using plates and screws through 2 separate small incisions located on the symphysis pubis and the posterior part of iliac crest,respectively.The posterior components of the acetabular fractures were reduced and fixated by the Kocher-Langenbeck(K-L) approach.Only the modified two-window approaches were used for 6 anterior column fractures,and the other 9 cases used the K-L approach in addition to the modified two-window approaches.The operation time,intra-operative blood loss and postoperative complications were recorded.The quality of fracture reduction was judged according to the Matta scheme and the clinical outcome was measured using the Merle d' Aubigné-Postel rating system.Results All the 15 patients were followed for an average of 15 months (from 9 to 19 months).The mean operation time for the 15 patients was 223.3 ±85.8 minutes and the intra-operative blood loss averaged 993.3 ± 416.6 mL.Anatomical reduction was achieved in all the patients according to the Matta scheme.Lateral femoral cutaneous nerve palsy was observed in one patient but recovered spontaneously one month after operation.The mean Merle d'Aubigné-Postel score at the last follow-up was 16.9 points (from 14 to 18 points).The outcome was defined as excellent in 6 patients,good in 8 and fair in one.No more complication was observed during the follow-up period.Conclusions The modified two-window ilioinguinal approaches can be used for satisfactory reduction and fixation of the anterior wall/column or the anterior components of acetabular fractures.In addition,the modified approaches do not invade very much the soft tissues or need to expose the femoral vessels and nerves.

Objective To investigate the risk factors of incidence of premature rupture of membranes and provide reference for prevention of premature rupture of membranes.Methods 890 cases of infants and maternal were studied,analyzing and screening the risk factors of premature rupture of membranes by Logistic.Results The single-factor analysis showed that the pregnant women with diabetes,pregnancy-induced hypertension,multiple preg-nancy and vaginifis had certain degree of contact with incidence of premature rupture of membranes.Multivariate Lo-gistic regression analysis showed that the multiple pregnancy and vaginitis were risk factors of incidence of premature rupture of membranes.Conclusion The multiple pregnancy and vaginitis were risk factors of incidence of premature rapture of membranes,assessment and control these risk factors could prevent and reduce the incidence of premature rupture of membranes.

Objective:To explore the process of maintenance management for large medical equipment, and the structure design and core connotation of the maintenance management software of them.Methods: Medical linear accelerator of Precise series of Elekta company was combined to achieve the objective. From the aim of designing normal operation rate to start, the failure mode and effects analysis (FMEA) was operated to analyze the maintenance strategies and maintenance manners which were established on the basis of PDCA(Plan, Do, Check, Action) cycle and the analysis mode of SWOT (Strength, Weakness, Opportunity, Threat), and it could achieve the aim of normal operation rate.Results: Through explored the connotation of maintenance management and the preliminary framework of the software of maintenance management, the detail and process of maintenance management that based on personalized accelerator of process control were established, and the element factors of software of maintenance management of accelerator also was established at the same time.Conclusion: The effective maintenance management of large medical equipment is based on informatization process management of process control, and the element factor of management software need personalized customization. On the other hand, failure mode and degradation mechanism of equipment were the basis for personalized customization, and the creation has practical value.