1.Role of new emergency mode "Green track" in treatment of traffic injuries
Chinese Journal of Trauma 2010;26(7):617-619
Objective To explore the role of new emergency mode "Green track" in treatment on traffic injuries. Methods The data of 2 947 patients with traffic injuries rescued by prehospital emergency "green track" and inhospital emergency treatment from March 1998 to January 2009 were retrospectively studied in aspects of prehospital and inhospital treatment methods and their results. Results Of all patients, 2 089 patients were treated surgically and 858 patients treated conservatively, in which 2 736 patients (92.8%) were cured but 211 (7.2%) died, with mortality rate of 7.2%. Head, face and limbs were the main injury parts. Of all, 1 874 patients (63.6% ) were admitted into the hospital within one hour after injury. Conclusions The new emergency mode "Green track" , either prehospital or inhospital, can markedly improve success rate of treatment for traffic injuries, increase survival rate and is of importance to be clinically applied.
2.Empirical study of autogenous dermal grafts in the prevention of epidoral fiSrosis and adhesions
Mushun HE ; Yuedong ZENG ; Zhiqiang QU
Chinese Journal of Orthopaedics 2009;29(8):765-770
Objective To investigate the ability of auto-dermis grafts in the prevention of epidural fibrosis and adhesions, and provide reference for clinical application. Methods Five Tibet mini-pigs were used and laminectomy was performed in lumbar 2 and 4 segment. Dura was exposed and covered with auto-genous dermis grafts in lumbar 2 (the experimental group), without grafts in lumbar 4 (the autogeoous blank group). The specimens were observed grossly and histologically at 2, 4, 6, 8 and 10 weeks postoperatively. Epidural scar amount and adhere range was evaluated by modified Robertson scoring method and analyzed by SPSS 13.0. No sear and adhesion, 0 point; small amount scar and light-range adhesion, 1 point; medium sear and midrange adhesion, 2 pionts; bulk scar ang high-range adhesion, 3 pionts. Results All grafted dermis survived and thicken obviously than dermis in body surface (P< 0.05). Hair growth, sebaceous gland cyst and sweat cystogenesis were not observed. A larvaceous dissection abruption plane, little cicatricial tis-sue and adhesions rarefaction between dermis and dura were observed in the experimental group. Massive ei-catricial tissue from erector spinae filled in cavitas epiduralis was observed and dura was separated difficult-ly from cicatricial tissue in the autogeous blank group. Epidural scar amount and adhesion range in the ex-perimental group was significantly lower than the blank group (P< 0.05). Conclusion Dermis is a kind of favourable biomaterial with restraining cicatrisation and isolation barrier. Autogenous dermis grafts has the best effect on preventing peridural cicatrisation and adhesion after laminectomy.
3.Clinical investigation on the correlation between lower urinary tract infection and cystitis glandularis.
Zhiqiang, CHEN ; Zhangqun, YE ; Wei, ZENG
Journal of Huazhong University of Science and Technology (Medical Sciences) 2004;24(3):303-4
In order to study the association between lower urinary tract infection and cystitis glandularis (CG), 120 cases of CG were diagnosed by cystoscopic biopsy in the suspicious foci of the bladder. Among them, 72 cases were subjected to bacterial counting culture of urine and microscopic examination of urinary sediment, and 60 cases to fluorescence quantitative polymerase chain reaction (FQ-PCR) assay to detect HPV, CMV and HSV DNA in urine samples. In the 72 cases of CG, the positive rate of bacterial counting culture of urine was 15.3% (11/72), and gray zone rate was 18.1% (13/72). 31.9% (23/72) patients were positive in bacterioscopy of urinary sediment. There was statistically significant difference as compared with the control group (P<0.01). Only 4 of 60 urine samples were positive by FQ-PCR in detection of the three viruses mentioned above with the positive rate being 6.67%. Compared with the control group, there was no significant difference (P>0.05). It was concluded that the genesis of CG was closely correlated with the chronic lower urinary tract infection, especially caused by Esch coli.
Cystitis/etiology
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Cystitis/microbiology
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Cystitis/*pathology
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*Escherichia coli Infections
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Metaplasia
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Urinary Bladder/microbiology
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Urinary Bladder/*pathology
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Urinary Tract Infections/complications
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Urinary Tract Infections/*microbiology
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Urinary Tract Infections/pathology
4.CLINICAL EFFECT OF SOCIALIZATION MANAGEMENT OF FAMILY-BASED COMMUNI-TY ON PATIENTS WITH HYPERTENSION
Haibo WEN ; Zhiqiang ZENG ; Yanjin LING
Modern Hospital 2015;(3):154-156
Objective To explore the curative effect of family -based socialization management on patients with hypertension in community .Methods A total of 116 patients with hypertension were randomly divided into ob-servation group and control group , 58 patients in each group .Both groups received conventional drug treatment .The control group was given routine chronic disease management and the observation group implemented social manage -ment(patients, families, doctors).Blood pressure(BP),lifestyle and psychological condition were evaluated , and the serum triglyceride ( TG) , low density lipoprotein ( LDL) and homocysteic acid ( Hcy) were detected after one year . Results Blood pressure of patients was dropped significantly in the two groups , as compared with the control group . The BP of patients in the observation group was declined more obviously , the BP up to standard rates , control rates and treatment compliance were raised , the mode of life and mental status were improved obviously , and the serum contents of TG, LDL and Hcy were decreased significantly (p<0.05).Conclusion The use of hypotensorscombined with fam-ily-based social management can effectively help patients to control their blood pressure , raise treatment compli-ance, establish a healthy life style and improve their mental status .The mode is worth of spreading in community .
5.Significance and expression of S100A9 and NMP238 in cervical carcinoma tissues with different concurrent chemoradiotherapy sensitivities
Hong ZHU ; Shan ZENG ; Liang ZENG ; Xuewei WANG ; Zhiqiang XIAO
Journal of Central South University(Medical Sciences) 2010;35(1):45-51
Objective To determine the significance and expression of S100A9 and NMP238 in cervical carcinoma with different concurrent chemoradiotherapy sensitivities. Methods Fresh carcinoma tissues were collected from untreated cervical carcinoma patients and preserved at -80 ℃. The tissues were classified into 2 groups:a high sensitivity group (HS) and a low sensitivity group(LS) according to their response to concurrent chemoradiotherapy. Protein was separated by 2-dimensional gel electrophoresis (2-DE). Peptide mass fingerprintings (PMF) were acquired by matrix assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) and the proteins were identified by data searching in the Mascot-database. Differential expressed proteins were assayed by Western blot and immunohistochemistry.Results Most of the gels were clear and were successfully and reproductively analyzed. Intensity and rate of S100A9 expression were higher in the HS group than in the LS group,and those of NMP238 expression were higher in the LS group than in the HS group. Conclusion S100A9 and NMP238 expression is associated with concurrent chemoradiotherapy sensitivity in cervical carcinoma.
6.Preparation of the inununo-kit of anti-THC monoclonal antibody labelled with colloidal gold
Liankang CHEN ; Libo ZENG ; Zhiqiang ZHAO ; Al ET
Chinese Journal of Forensic Medicine 1986;0(02):-
Objective To develop an accurate, rapid and simple colloidal gold immunochromatographic test (ICT) for detection of THC in urine. Methods Colloidal gold was prepared by reduction of HAuCl4 with trisodium citrate. Anti-THC monoclonal antibody was then labelled with the colloidal gold. THC-BTG conjugate was coated on nitrocellulose membrane to prepare test strip. Result could be detected by naked eyes because the competition for limited antibody binding sites on either THC-BTG conjugate or free THC which may be present in urine samples. Results A total of 216 urine samples were detected for THC by ICT and GC/MS. The detecting limit of the ICT was 50ng/ml, the sensitivity waw 96.67% and the accuracy was 98.61%. Conclusion ICT is a specific assay for detection of THC in urine.
7.Research advances in modern operation power device of skull bore
Yijun GUO ; Shaoxi CAI ; Zhiqiang ZHAO ; Chuisheng ZENG ; Wei WANG
Chinese Medical Equipment Journal 1989;0(04):-
Skull bore device has an important role in neurosurgery.This review is a summary of the development,current research status and advances of skull bore.The electrical operation power device is the emphasis in the review.It is important to develop newly operation power devices for human health.
8.Aesthetic correction of septal deviation with nasal deformify
Gao ZENG ; Haihuan MA ; Zhiqiang XUE ; Xiaogen HU
Chinese Journal of Medical Aesthetics and Cosmetology 2011;17(4):257-259,265
Objectives To explore a comprehensive approach for the functional and aesthetic correction of septal deviation. Methods From Jan. 2007 to Dec. 2009, 48 patients with deviation of the frontier and ceiling border of the septal cartilage, 6 males, 42 females, average age of 26.5 years, were surgically treated with a comprehensive use of several techniques, such as septoplasty, reconstruction of septal support, precise osteotomies and nasal tip plasty. Results Functional improvement achieved in all the patients, contour satisfaction achieved in 91.7 % patients; 30 patients were very satisfied, and 14 satisfied with the outcome. Conclusions With the thorough understanding of surgical anatomy of the nose and the use of comprehensive surgical approach, satisfactory outcomes can be achieved both functionally and aesthetically in patients with septal deviation.
9.Bone morphogenetic protein and bone defect repair
Zhiqiang QU ; Mushun HE ; Yuedong ZENG ; Yu DAI
Chinese Journal of Tissue Engineering Research 2007;0(02):-
Physical continuity of bone is damaged following bone defects. The use of exogenous bone morphogenetic protein (BMP) treatment depends on appropriate carrier, which releases exogenous BMP and other growth factor into the bone defect site, inducing new bone formation and achieving therapeutic purposes. There are many carrier materials for BMP, including inorganic material, synthetic polymers, biological material, and composites of these three materials. But all have some deficiencies. So many researchers have optimized them by combined, physical and chemical methods to improve the bone inductive activity. BMP, which is released from carrier or local gene, can repair bone defect effectively, affording a new way for bone defect repairing.
10.Elongating Asian nose with autologous septal cartilage
Gao ZENG ; Zhiqiang XUE ; Zhanwei GAO ; Haihuan MA
Chinese Journal of Medical Aesthetics and Cosmetology 2012;18(3):167-169,172
Objective To employ autologous septal cartilage grafting as a new method of elongating the nose and adjusting the nasolabial angle in order to correct the deformities of short nose and bulbous tip.Methods A set of techniques,including,yet not limited to,releasing and sculpturing of the alar cartilages,harvesting of septal cartilages and carving them into L shape and cap-like shape for transplant,moulding the soft tissue envelop with buried through and through sutures etc.were used to lengthen the nose and modify the tip.Results From 2004 to now,the new technique had been applied to 345 patients with short nose and bulbous tip.Follow-up ranged from 6- 48 months,satisfactory outcomes were obtained.Conclusions The new technique adopted by the author in which autologous septal cartilages are settled to the anterior angle of the nasal septum and between the domes of alar cartilages has been proved to be a viable and reliable way to lengthen the nose.Further advantages of this technique include the easiness of harvesting grafts,minimal injury,rare complications of infection and rejection etc.