1.Discussion on Academic Thought of Professor ZHAO Zhiqiang Syndrone Differentiation and Treatment of Adenomatous Polyp of Colon
Journal of Zhejiang Chinese Medical University 2017;41(1):75-77,83
Objective]The paper summarizes academic thought of Professor ZHAO Zhiqiang syndrome differentiation and treatment of adenomatous polyp of colon. [Method]By learning from ZHAO Zhiqiang and studying the medical record of adenomatous polyp of colon,sum up professor ZHAO Zhiqiang′ s experiences from etiology and pathogenesis, differential treatment, administered medical herbs and prescription ,and with one case for detailed explanation. [Results] Professor ZHAO thinks that the pathogeny raletes to exopathy, diet, emotion, weakness of the spleen and stomach, physique, smoke poison,influence of other diseases,the key of pathogenesis is phlegm, blood stasis and toxin stagnation, accumulation of intestine, Qi is out of adjustment, the conduction loss of us, He believes that the syndrome diagnosis of the disease is different from others, the syndrome diagnosis should include disease syndrome elements, syndrome elements of disease location and morbid state, disease syndrome elements should need the help of the modern medical endoscope and pathology, and ill treatment to detoxify the anti-cancer variable as the core, supplemented with Ruanjian Sanjie,coordinating zang and fu, modification according to symptoms.[Conclusion] Professor ZHAO's treatment of adenomatous polyp of colon has rich experience and prominent features, it is worth clinical promotion.
2.Thinking of the fairness about family planning services in urban and rural
Chinese Medical Ethics 1994;0(06):-
The paper discusses the problems and inequity in town and country family-planning service by comparing the following aspects: work thinking in the service,accessibility of family-planning service,service capacity of the organizations,resource allocation.Besides,in order to satisfy the demand of rural family-planning service market and improve the equity,some suggestions,such as integrating resource and complementing advantages to implement regional family-planning program,identifying the functions of government and changing the service thinking,increasing the investment in primary health family-planning organizations and reinforcing the co-operation between health and family-planning organizations.
3.Targeting~(131)I labeled monoclonal antibody against vascular endothelial cells for treatment of hepatocarcinoma
Hongtian XIA ; Zhiqiang HUANG ; Mei YUAN
Medical Journal of Chinese People's Liberation Army 2001;0(11):-
Objective To study the possibility of targeting endothelial cells with the 131I labeled monoclonal antibody (mAb) for the treatment of hepatocarcinoma. Methods An animal model of human hepatocarcinoma in nude mice was reproduced, and tumor inhibiting activity of the 131I labeled mAb was tested. 30 nude mice with hepatocarcinoma were randomly divided into 3 groups: in group A the mice were treated with mAb 200?g/200?l twice a week; group B mice were treated with the 131I labeled mAb 200?g/200?l twice a week; control group mice were given normal saline in equal volume. Tumor growth in mice was observed. After the mice were sacrificed, the tumor was histologically examined and the intra-tumor microvessel density (TMVD) recorded. Results The tumor growth inhibition effect in mice treated with mAb was 74.55%. This effect was enhanced when treated with the 131I labeled mAb, as evidenced by an increase of tumor growth inhibition rate to 86.36%. Pathologically, Massive necrosis of tumor cells around the degenerated vessels was observed in the mAb treated mice. TMVD was significantly lower in the mAb treated mice than that in the untreated mice (P
4.Knowledge of voluntary blood donation and factors influencing the willingness among rural residents in Anhui
Xiaomei WANG ; Yan DOU ; Zhiqiang XIA
Chinese Journal of Blood Transfusion 2008;0(08):-
Objective To get a general idea of the knowing level of knowledge and policies related to voluntary blood donation among rural residents,and to explore factors influencing their willingness of voluntary blood donation.Methods Three natural villages were randomly chosen in the north,middle and south of Anhui province as the investigation sites in Jan.2008.Data were collected by interviewing the target people,as well as using a self-designed questionnaire.A total of 724 people were interviewed and 620 valid questionnaires were obtained,with an effective retrieval rate of 85.6%.Results The score of voluntary blood donation knowledge among rural residents was 19.26?3.987,and the score of relevant policy knowledge was 5.85?2.154.There were significant differences in knowledge of both voluntary blood donation and relevant policies among different age groups.Residents with different education levels also differed significantly in knowledge of relevant policies.Logistic analysis indicated that age,education and knowing level of relevant policies were the factors that had influence people's willingness of voluntary blood donation.Conclusion Knowing level of voluntary blood donation knowledge is high among rural residents while the policy knowledge level is low.Willingness of blood donation among the group of age 25 to 34 is obviously higher than that of the group of age 18 to 24;willingness of people with middle school education background is lower than illiterate people;the higher the knowledge level,the higher of people's willingness.
5.The Traceability Management for Qualification Documents of Medical Instruments.
Guoping TANG ; Liang HU ; Xia XU ; Zhiqiang FANG ; Juan HU
Chinese Journal of Medical Instrumentation 2016;40(1):70-76
The management for qualification documents of medical instruments is very important work to management department of medical instruments. Because the number of qualification documents of medical instruments is very large and they have an expiry date, it is difficult to manage them. This article discussed how to manage qualification documents of medical instruments, and an information management system that has a function of traceability management has been developed. This information management system standardizes management for qualification documents of medical instruments, and ensures that qualification documents of medical instruments are available and can be traced. Besides, it can reduce the amount of work for medical instruments management.
Documentation
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standards
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Equipment and Supplies
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standards
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Information Systems
6.Clinical analysis of endoscopic treatment for patients with gastric submucosal tumors (61 cases)
Yuhong REN ; Zhiqiang ZHANG ; Hongliang GAO ; Yu XIA ; Ping YAO
China Journal of Endoscopy 2016;22(3):18-22
Objectives To analyze the clinical and pathological characteristics of gastric submucosal tumors (GSMTs), and evaluate the safety and efficacy of endoscopic treatment for GSMTs. Methods 61 patients with GSMTs were selected from June 2014 to September 2012 by endoscopy and ultrasonography;they were all treated by endoscopic therapy; pathological examination was took in all removed tumors, the tumors which could be the gastric stromal tumor were furtherly examined by molecular biology technique of immunohistochemistry. Result In 61 cas-es, 39 cases are female patients, accounting for 63.93%;the tumors located at the stomach fund accounted for 52.46%(32/61), at the gastric corpus for 21.31%(13/61), at the gastric antrum for 11.48 %(7/61), at cardia for 14.75%(9/61); 10 cases were treated by Endoscopic submucosal dissection, 21 by endoscopic submucosal excavation, 27 by Endoscopic full-thickness resection, 3 by Submucosal tunnelling endoscopic resection; in all 61 cases, 2 were changed to laparoscopic treatment because one tumor was too big and broke the Serous and another was located at mucus Lake of gastric fund, 1 occurred postoperative bleeding and was treated by laparoscopy successfully, 1 oc-curred postoperative perforation and was treated by endoscopy successfully; after pathological and immunohisto-chemical analysis, 34 tumors were identified as gastric stromal tumor and all of them in risk classification were at very low risk, 11 were leiomyoma, 5 were lipoma, 3 were heterotopic pancreas, 5 were calcifying fibrous pseudotu-mor, 2 were inflammatory fibroid polyps, and 1 was angiomatous proliferation; gastric stromal tumor at gastric fundus account for 73.53 % (25/34), at gastric corpus for 11.76 % (4/34), at gastric antrum for 5.88 % (2/34) and at cardia for 8.82 %(3/34). Conclusion Most GSMTs are found in female and commonly lack of specific clinical symptoms;GMSTs are commonly located at gastric fund and most of them are gastric stromal tumors, vast majority of gastric stromal tumors in the risk classification are at very low risk;the endoscopic resection is a mini-invasive, safe and ef-fective treatment for GSMTs.
7.Efficacy and Safety of Magnesium Isoglycyrrhizinate Injection versus 4 Common Medicines in the Treatment of Drug-induced Liver Damage:A Systematic Review
Zhiqiang LI ; Chunhui XIA ; Yajing WANG ; Guanda WANG ; Junqing SHI
China Pharmacy 2015;26(33):4678-4681
OBJECTIVE:To systematically review the efficacy and safety of Magnesium isoglycyrrhizinate injection versus 4 comnon medicines in the treatment of drug-induced liver damage,and to provide evidence-based reference for clinic treatment. METHODS:Retrieved from PubMed,EMBase,Cochrane Library,CBM,CJFD,Wanfang Database and VIP Database,random-ized controlled trials (RCT) about Magnesium isoglycyrrhizinate injection versus other medicines in the treatment of drug-induced liver damage were enrolled. Meta-analysis was performed by using Rev Man 5.3 software after literature selection,data extract and quality assessment. RESULTS:A total of 13 RCTs were included,involving 1 093 patients. Results of Meta-analysis showed clini-cal effective in magnesium isoglycyrrhizinate group was significantly higher than tiopronin group[RD=0.29,95%CI(0.17,0.42), P<0.001] and diammonium glycyrrhizinate group [RD=0.07,95%CI(0.01,0.12),P=0.02],compared with glutathione group and compound ammonium glycyrrhetate group,there were no significant differences ;incidence of adverse reactions in magnesium iso-glycyrrhizinate group was significantly lower than diammonium glycyrrhizinate group [RD=-0.07,95%CI(-0.11,-0.03),P<0.001] and compound ammonium glycyrrhetate group[RD=-0.21,95%CI(-0.38,-0.04),P=0.02],compared with triopro-nin group and glutathione group,there were no significant differences among 3 groups. CONCLUSIONS:Magnesium isoglycyrrhiz-inate injection has better efficacy and safety than other 4 commons hepatoprotective medicines in the treatment of drug-induced liver damage. Due to the limit of methodological quality,more large-scale and long-term follow-up studies with strict designed are need-ed for the further verification of the conclusion.
8.Visualization of Normal and Abnormal Sternum with Multislice Spiral CT
Deting MA ; Xia WANG ; Limin WANG ; Zhiqiang LIU
Journal of Practical Radiology 2001;0(05):-
Objective To investigate the imaging methods of multislice spiral CT (MSCT) of sternum and its diagnostic value in the sternum diseases.Methods 108 cases(100 cases in normal group and 8 cases in disorder group) underwent conventional chest volume scan and thin slice low contrast images reconstruction with 16-slice spiral CT.Then all the source images were processed using standard/curved multiplanar reconstruction(MPR), maximum intensity projection(MIP), surface shaded display (SSD) and volume rendering technique(VRT). All post-processed images were observed and analyzed by two radiologists. Results The sternums were clearly showed by the post-processed images.In displaying the structure of sternum, sagittal MPR was better than axial MPR (U=14.107, P=0.000) and coronal curve MPR was better than coronal MPR (U =11.882, P=0.000); in evaluating the shape of sternum , VRT was better than the imaging modes of MIP, SSD(UVRT:MIP =13.553, UVRT:SSD=12.102, P=0.000). Among 8 patients with sternum diseases, 5 cases of sternum fracture and 3 cases of sternum metastasis tumor were found. Conclusion Coronal curve MPR, sagittal MPR and VRT are the best imaging methods of MSCT to show sternum and they are markedly superior to conventional X-ray images and axial CT images in evaluating the sternum diseases.
9.Abnormal DNA-binding abilities of NF-?B and glucocorticoid receptor in cortex of kindey from rats with Adriamycin-induced nephrosis
Runmin ZHAO ; Siguang LU ; Yu CHEN ; Changchun CAO ; Zhiqiang XIA
Journal of Chinese Physician 2001;0(05):-
Objective To explore the role of transcription factors such as nuclear factor-kappa B(NF-?B) and glucocorticoid receptor(GR) in the pathogenesis of Adriamycin(ADM)-induced nephrosis in rats and the therapeutic effects of dexamethasone(Dex) and cyclosporin(CsA) on these animals.Methods The DNA-binding abilities of NF-?B and GR in cortex of kindey were examined with electrophoretic mobility shift assay(EMSA) and isotopic radioautography on the 7th,14th,21th and 28th day after a single intravenous injection of ADM,and the therapeutic effects of Dex and CsA were estimated.The biochemistry parameters from blood and urine of rats and the urine protein excretion were also measured.Results The NF-?B DNA-binding ability was significantly increased after 7 days and achieved maximum after 28 days(P0.05).Conclusion The DNA-binding ability of NF-?B is abnormally increased and that of GR is decreased in cells from cortex of kindey in Adriamycin-induced nephrotic rats.The NF-?B DNA-binding ability can be inhibited and the urine protein excretion is decreased by the treatment of CsA.
10.Analysis of Liposoluble Constituents in Fruit of Cnidium Monnieri by GC-MS
Zhiqiang JI ; Jianmin ZHANG ; Junmei XIA ; Guangdong NIU
China Pharmacist 2015;(11):1892-1894
Objective:To investigate the liposoluble constituents in fruit of Cnidium monnieri. Methods:The liposoluble constitu-ents in fruit of C. monnieri were extracted by Soxet extraction. The extracted liposoluble constituents were methyl esterified and then analyzed by GC-MS for the first time. Results:Thirty-nine compounds (85. 33%) were identified from the liposoluble constituents in fruit of C. monnieri. Phytol (15. 98%), hexadecanoic acid (12. 73%), 9,12,15-octadecatrienoic acid (11. 02%), 9-octadecenoic acid (6. 33%) and 9,12-octadecadienoic acid (4. 77%) were the main constituents of the liposoluble constituents in fruit of C. mon-nieri. Conclusion:Phytol, hexadecanoic acid, 9,12,15-octadecatrienoic acid and 9-octadecenoic acid are the active ingredients in fruit of C. monnieri.