1.Investigation on Formaldehyde Pollution Caused by Furniture in Tunnel
Journal of Environment and Health 2007;0(07):-
Objective To investigate the formaldehyde pollution in a tunnel. Methods The concentration of formaldehyde was determined in rooms for different function,in rooms with different number of furniture,in different position in a tunnel and at different time of using air cleaner in Oct. 2006. Results The total rate of exceed standard of formaldehyde level in the tunnel was 82.9%,the rate of exceed standard in the rooms disposed by all the furniture was 100%,the rate of exceed standard in the front of the tunnel was lowest (63.6%). Using the air cleaner,the rate of exceed standard decreased in degree. Conclusion The main source of formaldehyde pollution in a tunnel is furniture,formaldehyde is the main air pollutant in a tunnel.
2.Orexin A and cerebrovascular diseases
International Journal of Cerebrovascular Diseases 2015;(5):374-377
Orexins are a class of important hypothalamic neuropeptides,including type A and B. Orexins are associated w ith numerous physiological functions, including sleep-aw akening, energy balance, endocrine and visceral functions, and they also have certain relations w ith the pathophysiological changes, such as drow siness and drug abuse. In recent years, the pathophysiological role and mechanism, as w el as the clinical significance of orexins in cerebrovascular diseases are causing concern. This article summarizes the roles of orexins and focuses on the roles of orexin A in cerebrovascular diseases.
3.Thyroid autoantibodies and intracranial artery stenosis
International Journal of Cerebrovascular Diseases 2021;29(2):152-155
Since it has been found that autoimmune thyroid diseases (Graves' disease and moyamoya disease) may have a causal relationship mediated by immune mechanism, the relationship between thyroid autoantibodies and cerebrovascular diseases has attracted more and more attention. Recent studies have shown that thyroid antibody abnormalities can affect the occurrence and development of vascular events. Therefore, this article reviews the relationship between thyroid autoantibodies and intracranial artery stenosis and the related mechanism.
4.The effect of the ganoderma lucidum spore on the immunoregulation of the immunosuppression mice
Wei REN ; Li ZUO ; Zhiqiang ZHONG
Chinese Journal of Immunology 2000;0(11):-
Objective:To explore the effects of Ganoderma Lucidum spore on the immunity of the immunosuppression mice with Glucocorticiods(GC).Methods:Different dosages of Ganoderma Lucidum spore were intragastriced to the immunosuppression mice with Glucocorticiods, and the weight of the immune organs and the phagocytic function of the macrophages and neutrophile,the expression in of CD3+,CD4+,CD8+,CD49b+ and CD19+ in the blood cell were measured;And the total complement activity, the content of the cytokine and the valence of hemolysin in the mice serum were detected.Results:The immune function of the GC immunosuppression mice were remarkable effected with Ganoderma Lucidum spore, it could significantly increase the index of the thymus and spleen, improve the valence of hemolysin and the phagocytic function of the macrophages and neutrophile of the mice.The total complement activity, the content of the cytokine in serum,and the quantity of T,B and NK cell in the mice blood were influenced by Ganoderma Lucidum spore.Conclusion:The results show that Ganoderma Lucidum spore remarkable effect on the immunity of the immunosuppression mice with GC, and it can promote accommodation the immune function of mouse.
5.hMSH6 polymorphisms and cancer susceptibility
Wei LIU ; Zhiqiang LING ; Weimin MAO
Journal of International Oncology 2011;38(4):243-245
hMSH6 is one of the most important members in the mismatch repair family. Its polymorphism is closely related to the pathogenesis and development of neoplasm, particularly in colorectal cancer and endometrial cancer. Moreover, it has been suggested to play a more important role in endometrial cancer compared with hMLH1 and hMSH2.
6.Prognostic factors of acute exacerbation of chronic obstructive pulmonary disease
Zhiqiang LV ; Yun CHEN ; Wei ZHANG
Journal of Chinese Physician 2011;13(12):1611-1614,1620
ObjectiveTo investigate prognostic factors in acute exacerbation of COPD (AECOPD).Methods352 AECOPD patients were investigated.26 possible variables were analyzed.Multivariate Logistic and Cox proportional-hazards regression analysis were used.ResultsAccording to multivariate Logistic regression,it showed seven factors were statistically significant for short term prognosis ( P <0.05 ),including PaO2 ( OR =0.082),CKMB ( OR =4.967 ),mechanical ventilation ( OR =6.903 ),albumin ( OR =0.221 ),FEV1% ( OR =0.255 ),charlson index ( OR =8.406 ) and hospital day ( OR =0.075).According to multivariate Cox regression,it showed seven factors were statistically significant for long term survival ( P < 0.05 ) including acute exacerbation frequency( HR =1.611 ),charlson index( HR =4.319),SaO2 ( HR =0.224 ),troponin Ⅰ ( HR =3.824 ),albumin ( HR =0.569 ),hospital day ( HR =0.456) and FEV1% (HR =0.494).Acute exacerbation frequency was correlated with dyspnea scale( rs =0.508,P < 0.01 ).ConclusionsPaO2,albumin,FEV1%,CKMB and charlson index were related with short term prognosis.SaO2,albumin,FEV1 %,troponin Ⅰ,charlson index and acute exacerbation frequency were related with long term survival.Higher acute exacerbation frequency contributed to more severe breathing difficulties and worse quality of life.
7.Video-assisted thoracoscopy in the diagnosis and treatment of pleural effusion with unknown causes
Qingdong CAO ; Zhiqiang XIE ; Wei HE
Chinese Journal of Minimally Invasive Surgery 2005;0(11):-
Objective To investigate the value of video-assisted thoracoscopy in the diagnosis and treatment of pleural effusion with unknown causes.Methods Video-assisted thoracoscopic biopsy or pleurodesis was performed in 45 cases of pleural effusion unexplained by routine examinations from March 2002 to March 2005.Results The diagnosis was clarified in all the 45 cases.There were 3 cases of malignant effusion,38 cases of tuberculous pleurisy,3 cases of nonspecific effusion,and 1 case of idiopathic pleural effusion.No severe surgical complications occurred.Follow-up checkups for 2~36 months found no recurrence.Conclusions Video-assisted thoracoscopy is a safe,effective,and micro-traumatic approach for the diagnosis and treatment of pleural effusion.
8.A radiographic measurement of the width of the intercondylar notch
Zhiqiang ZHANG ; Xiaochun WEI ; Bufang RENG
Chinese Journal of Radiology 2000;0(12):-
0.05). The notch width index was 0.24?0.05. There was no correlation between the notch width index and the height (r=-0.11), the body weight (r=-0.13), and the age (r=-0.28). Conclusion The notch-view radiographs with 45? flexion of the knee can satisfactorily show the shape and the width of the intercondylar notch. The notch width and the notch width index of the normal knee are (18.9?4.8) mm and 0.24?0.05, respectively. The height and the body weight can′t be used to predict the notch width. The study supplies the radiographic basis for the diagnosis and treatment of the diseases related with the femoral intercondylar notch.
9.Clinical investigation on the correlation between lower urinary tract infection and cystitis glandularis.
Zhiqiang, CHEN ; Zhangqun, YE ; Wei, ZENG
Journal of Huazhong University of Science and Technology (Medical Sciences) 2004;24(3):303-4
In order to study the association between lower urinary tract infection and cystitis glandularis (CG), 120 cases of CG were diagnosed by cystoscopic biopsy in the suspicious foci of the bladder. Among them, 72 cases were subjected to bacterial counting culture of urine and microscopic examination of urinary sediment, and 60 cases to fluorescence quantitative polymerase chain reaction (FQ-PCR) assay to detect HPV, CMV and HSV DNA in urine samples. In the 72 cases of CG, the positive rate of bacterial counting culture of urine was 15.3% (11/72), and gray zone rate was 18.1% (13/72). 31.9% (23/72) patients were positive in bacterioscopy of urinary sediment. There was statistically significant difference as compared with the control group (P<0.01). Only 4 of 60 urine samples were positive by FQ-PCR in detection of the three viruses mentioned above with the positive rate being 6.67%. Compared with the control group, there was no significant difference (P>0.05). It was concluded that the genesis of CG was closely correlated with the chronic lower urinary tract infection, especially caused by Esch coli.
Cystitis/etiology
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Cystitis/microbiology
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Cystitis/*pathology
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*Escherichia coli Infections
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Metaplasia
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Urinary Bladder/microbiology
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Urinary Bladder/*pathology
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Urinary Tract Infections/complications
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Urinary Tract Infections/*microbiology
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Urinary Tract Infections/pathology
10.Relationship between different types of acute ischemic stroke in elderly patients with serum OX-LDL,blood sugar, CRP amd IL-6
Zhiqiang ZHONG ; Wei WU ; Zhujia ZHENG
Chinese Journal of Primary Medicine and Pharmacy 2012;19(4):517-519
Objective To investigate the relationship between different types of acute ischemic stroke in elderly patients and serum oxidized low-density lipoprotein (OX-LDL),blood sugar,C-reactive protein(CRP) and interleukin 6 (IL-6) levels.Methods 100 patients with acute cerebral infarction (group A) and 30 heathy patients (group B)were investigated.The levels of serum OX-LDL,blood sugar,CRP and IL-6 were detected by automatic biochemical analysis.Results The levels of OX-LDL(627.2 ± 174.7 ) μg/L,blood sugar ( 8.8 ± 1.7 ) mmol/L,CRP ( 107.5 ±19.4)mg/L and IL-6(79.5 ± 12.1 )ng/L in patients of group A were significantly higher than group B[ OX-LDL(506.1 ± 152.4) μg/L,blood sugar(6.9 ± 1.5) mmol/L,CRP(87.2 ± 13.6) mg/L and IL-6(58.5 ± 10.3) ng/L](t=2.74,3.18,2.61,2.91,allP<0.05).Conclusion Elderly patients with acute cerebral infarction were closely related to the elevated levels of plasma OX-LDL,blood sugar,CRP and IL-6.Increased plasma OX-LDL was a risk factor for the main artery atherosclerosis type,and hyperglycemia was primary factor for the small artery atherosclerosis type of acute cerebral infarction.