In this article, a method to determine the content of liquiritin, ammonium glycyrrhetate, costunolide and dehydrocostus lactone in Mongolia medicine Ga Ri Di-13 pill was established. The chromatographic condition for liquiritin and ammonium glycyrrhetate was listed as the below: with Dimma column (250 mm×4.6 mm, 5μm) as stationary phase; with acetonitrile (A)-0.4%phosphoric acid (B) as mobile phase; gradient elution: 0-10 min (16%-18% A), 10-30 min (18% A), 30-40 min (18%-27% A), 40-85 min (27%-45% A), and 85-86 min (45%-16%A); column temperature was set at 30℃; detection wavelength was 237 nm; and flow velocity was 1 mL·min-1. The chromatographic column condition for costunalide and dehydrocostus lactone was listed as the below: with Dimma column (250 mm×4.6 mm, 5μm) as stationary phase; with acetonitrile-water (65:35) as mobile phase; detection wavelength was 225 nm; column temperature was set at 30℃ and flow velocity was 1.0 mL·min-1. The linearity ranges of liquiritin, ammonium glycyrrhetate, costunolide, and dehydrocostus lactone were 0.1-1.2μg (r=0.999 9), 0.341-4.092μg (r=1.000 0), 0.12-1.2μg (r=1.000 0), and 0.106-1.06 (r=1.000 0), respectively; the average recovery rates were 97.07%, 100.13%, 98.44%, and 98.90%, respectively; the RSD were 1.00%, 1.84%, 2.21% and 3.38%,respectively. This method is specificity and reproducible, and can be used to determination of liquiritin, ammonium glycyrrhetate, costunolide and dehydrocostus lactone in Mongolia medicine Ga Ri Di -13 pill.

Projects of hospital reorganization and expansion can be put on the track of scientific,fair,economical,rational,objective,and sustainable development through feasibility studies and first-phase planning and preparations,which ensure that hospital reorganization and expansion meet the requirements of national policies and regional health planning,the needs of the medical market and the medical system,and the demands of medical reform,thus avoiding any inherent weaknesses that projects of hospital reorganization and expansion might have.

OBJECTIVE To approach whole environment dynamic monitoring of the cross infection in operation department.METHODS To learn the experience of planning,construction and infection′s monitoring and managing of domestic and abroad operation departments,in combination with own work practice of reforming and infection management.RESULTS There were straight relations between planning,plane disposition,flow-sheet,construction quality,managing way and cross infection.CONCLUSIONS The whole environment dynamic monitoring of cross infection in operation department is very important.Of the total,the monitoring of planning design,the efficiency,rationality and safety of disposition,and flow-sheet of operation department at the beginning stage of construction is the premise of preventing and controlling cross infection there.The monitoring of construction quality at intermediate stage is the foundation of monitoring cross infection.The dynamic monitoring of alive human flow(patients,staff),logistic flow(articles during pre-operation,in-operation,and post-operation) and air current at later stage is the key point of preventing and controlling cross infection.

OBJECTIVETo investigate the relationship between the stages of calcification of the third molar and age among children in Chengdu.

METHODSThe study subjects consisted of children between 2009 and 2011 at the Department of Orthodontics, West China Hospital of Stomatology, Sichuan University. Panoramic radiographs were obtained. The stages of calcification of the third molar were analyzed by Demirjian's method. The development of the third molar between the male and female was evaluated by independent samples t-test analysis. The Spearman rank correlation was applied to analyze the stages of calcification of the third molar and chronological age.

RESULTSThe development of the third molar of the male was different from that of the female at stage A of calcification of the third molar(P=0.026). The Spearman rank correlation coefficient revealed highly significant relationships between the stages of calcification of the third molar and chronological age of the three groups (male, r=0.808, P=0.000; female, r= 0.729, P=0.000; all, r=0.760, P=0.000). Furthermore, the linear regression equations were established as follows: Yall= 4.898+2.036X: Ymale=4.987+2.046X; Yfemale=4.819+2.036X.

CONCLUSIONThe stages of calcification of the third molar may be an available indicator in judging chronological age of teenager.

Adolescent ; Age Determination by Teeth ; China ; Female ; Hospitals ; Humans ; Male ; Molar, Third ; Oral Medicine ; Radiography, Panoramic ; Universities

Patients with severe trauma require an extremely timely treatment and transfusion plays an irreplaceable role in the emergency treatment of such patients. An increasing number of evidence-based medicinal evidences and clinical practices suggest that patients with severe traumatic bleeding benefit from early transfusion of low-titer group O whole blood or hemostatic resuscitation with red blood cells, plasma and platelet of a balanced ratio. However, the current domestic mode of blood supply cannot fully meet the requirements of timely and effective blood transfusion for emergency treatment of patients with severe trauma in clinical practice. In order to solve the key problems in blood supply and blood transfusion strategies for emergency treatment of severe trauma, Branch of Clinical Transfusion Medicine of Chinese Medical Association, Group for Trauma Emergency Care and Multiple Injuries of Trauma Branch of Chinese Medical Association, Young Scholar Group of Disaster Medicine Branch of Chinese Medical Association organized domestic experts of blood transfusion medicine and trauma treatment to jointly formulate Chinese expert consensus on blood support mode and blood transfusion strategies for emergency treatment of severe trauma patients ( version 2024). Based on the evidence-based medical evidence and Delphi method of expert consultation and voting, 10 recommendations were put forward from two aspects of blood support mode and transfusion strategies, aiming to provide a reference for transfusion resuscitation in the emergency treatment of severe trauma and further improve the success rate of treatment of patients with severe trauma.