1.A Research into Medical Consumers' rights and Quties——A summary of research into rights and duties ofdomestic, alien patients
Qingxiu GUO ; Zhiping FENG ; Lifei WANG
Chinese Medical Ethics 1995;0(03):-
After summing up history and current situation of qlien patients rights and duties, the paper empha-sices on domestic patients' rights and duties, It will have great theortic and practiced significance touords perfecting our newly built medical morbet. confirming medical consumers' benffits and improving medical morals basical-ly.
2.CT diagnosis of small bowel obstruction in children
Xin LI ; Zhiping GUO ; Bin ZHAO
Chinese Journal of Radiology 2001;0(08):-
Objective To evaluate CT in the diagnosis of small bowel obstruction in children. Methods Thirty one cases with small bowel obstruction manifestations on CT and plain radiograph were analysed. The age ranged from 9 months to 14 years, male 17 cases, female 14 cases. There were 29 acute small bowel obstructions, and 2 chronic obstruction. Seven cases had history of previous abdominal operation. Results Corred diagnosis was made in 19 cases and 29 cases respectively by plain film and CT. The accurate etiologic diagnosis could be made by CT in 18 cases, including small bowell stone 4 cases, intussusception, 5 localized infection and adhesion 6 intraluminal bowel duplication, 1 congenital umbilical hernia, congenital malrotation of the intestine 1 case.Combined with history of abdominal operation the accurate CT etiologic diagnosis increased to 25 cases.There were 4 CT false negative cases and 2 plain film false negative cases. Conclusion The CT is obviously superior to plain radiograph in detecting strangulation and gas in bowel wall,better dilineating the transitional segment of bowel stenosis thereby demonstrating the case of obstruction which is very helpful for clinical management.
3.MRI Diagnosis of Discoid Meniscus
Xiaohui MA ; Jian ZHAO ; Shiling LI ; Min ZHANG ; Zhiping GUO
Journal of Practical Radiology 2001;0(05):-
Objective To investigate the MRI signs of discoid meniscus and to establish the criterion of MRI diagnosis.Methods 40 cases of discoid meniscus were analysed retrospectively. The methods of measurement and the classification of discoid meniscus were studied. Besides, the injurious criterion of diagnosis were discussed.Results All of 40 cases were lateral discoid meniscus. 24 cases were classified as slab type and 16 cases wedge type. 38 cases developed in different degree of meniscal injury. The rate of injury was 95%. Conclusion MRI examination is principal in diagnosis of discoid meniscus. Proportion of transverse diameter of the midbody of meniscus to the transverse width of the tibia exceeded 40%, which is necessary to diagnose discoid meniscus.
4.Analysis of Technique in 64-slice Spiral CT Angiography
Xiaohui MA ; Yingcai SUN ; Shiling LI ; Zhiping GUO ; Jian ZHAO
Journal of Practical Radiology 2000;0(02):-
Objective To explore scanning technique in 64-slice spiral CT angiography, and to evaluate the clinical value of various of post-processing methods.Methods 45 patients were examined with CT angiography, including 4 cases of thoracic aorta, 15 cases of abdominal aorta,10 cases of pulmonary artery, which delay time was determined by bolus tracking. The delay time of others ,including 4 cases of cerebrovascular, 6 cases of cervicum blood vessel and 6 cases of lower limb artery were determined by artifical. The initial images were processed with MPR, CPR, MIP ,SSD and VRT.Results According to standard valuation of imaging quality ,the good images were 37 cases, the better were 8 cases and none was bad.Conclusion As far as the diagnosis of great vessels is concerned, 64-slice spiral CTA can instead of DSA. MIP and VRT are important methods in post-processing of image.
5.Diagnosis and classification of abdominal enterogenous cysts in infant
Wan CHEN ; Cuiping GUO ; Zhiping CHEN ; Qiang ZHOU
Journal of Practical Radiology 2015;(4):634-637
Objective To explore the definition,classification and imaging characteristics of abdominal enterogenous cysts in in-fant.Methods 18 patients with abdominal enterogenous cyst in infant,confirmed by surgical pathology,with complete imaging data (including ultrasonography,CT and enhanced CT),have been enrolled in the study.The imaging findings and pathological character-istics have been analyzed,and the classification of diagnosis has been conducted.Results According to the positions and imaging fea-tures of the pathological changes,abdominal enterogenous cysts could be further classified as:gastrointestinal wall type,mesenteric type and retroperitoneal type.In this study,gastrointestinal wall type in 1 1 patients (outside intestinal wall in 2,inside intestinal wall in 8,and outside gastric wall in 1);mesenteric type in 4 and retroperitoneal type in 3 were identified.Conclusion Classification of diagnosis can be conducted according to the enterogenous cyst’s special imaging findings,which provides a reference for the surgical operation.
6.Therapeutic effects and pathways of human umbilical cord mesenchymal stem cells transplantation for rat acute liver failure model
Sheng ZHENG ; Juan YANG ; Fang YIN ; Qiongyi XIAO ; Zhiping GUO
Chinese Journal of Organ Transplantation 2014;35(12):747-752
Objective To explore the therapeutic effectiveness and pathways of human umbilical cord mesenchymal stem cells (hUCMSCs) transplantation for acute hepatic failure in rats.Method hUCMSCs were isolated from umbilical cord with attachment culture method,and the surface antigens were tested by flow cytometry.Forty-eight male Sprague Dawley rats were randomly divided into four groups.The animal model of acute liver failure was induced by injecting intraperitoneally with 50% olive oil solution of carbon tetrachloride (2.5 ml/kg).The treatment groups were injected with hUCMSCs suspension separately through the tail vein or injected into the liver 24 h post-modeling.Blood serum and liver tissues were collected at several time points to analyze the improvement of liver function and histological repair.Real-time PCR was used to detect the expression of human CK8,CK18 and AFP mRNA in liver tissues.Immunohistochemistry was used to detect the expression of human CK18 in liver tissues.Result There were statistically significant differences among liver functions after transplantation (P<0.05).hUCMSCs improved histological status through enhancing hepatocellular regeneration and reducing inflammatory cells.Real-time PCR results showed that the expression of CK8,CK18 and AFP mRNA was obviously increased in the tail vein transplantation group and hepatic lobe injection transplantation group as compared with the model group (P<0.05).Immunochemistry results revealed that transplanted hUCMSCs in animal liver could differentiate into functional hepatocyte-like cells that expressed human CK18 as hepatocyte-specific marker in the tail vein transplantation group and hepatic lobe injection transplantation group.No significant differences in histological repair and grade of differentiation were examined between the tail vein transplantation group and hepatic lobe injection transplantation group (P>0.05).Conclusion hUCMSCs can prompt the repair of acute liver failure and enhance pathological repair.Transplanted cells in animal liver can differentiate into functional hepatocyte-like cells that expressing hepatocyte-specific markers.Transplantation of hUCMSCs via the tail vein or direct injection into the liver had the similar therapeutic effects.
7.Systematic Review of Efficacy and Safety of the Treatment ofGuipi Decoction for Depression
Jingping TIAN ; Zehuai WEN ; Xinfeng GUO ; Yan LI ; Zhiping LV
Chinese Journal of Information on Traditional Chinese Medicine 2016;23(4):36-40
Objective To evaluate the efficacy and safety ofGuipi Decoction vs. antidepressants for depression. Methods Articles about the randomized controlled trials (RCTs) ofGuipi Decoction for depression were searched in the databases of CNKI, VIP, Wanfang Data, CMB, Embase, PubMed, and Cochrane Library. Two researchers independently screened the articles, extracted the data, and evaluated the methodological quality. Meta-analyses were performed by using RevMan 5.2 software.Results A total of 9 RCTs articles involving 893 cases were included. Meta-analysis results suggested that as compared with antidepressants only,Guipi Decoction together with antidepressants was associated with a significantly greater reduction in HAMD scores (MD=-4.63, 95%CI [-5.95, -3.32];P<0.001). There was no significant difference in HAMD scores betweenGuipi Decoction used alone and antidepressants (MD=-0.30, 95%CI [-4.22, 3.62];P=0.88). As compared with antidepressants,Guipi Decoction together with antidepressants increased in the rates of total effective events (RR=1.26, 95%CI [1.14, 1.38];P<0.001). No serious adverse reactions were reported. Meta-analysis results suggested that the incidence of adverse reactions of Guipi Decoction(RR=0.48, 95%CI [0.40, 0.58];P<0.001) andGuipi Decoction together with antidepressants (RR=0.51, 95%CI [0.30, 0.85];P=0.010) were lower than that of antidepressants alone.Conclusion The present evidence suggests thatGuipi Decoction is effective and relatively safe for patients with depression. However, because the quality of included research was low, more large-scale RCTs with multicenter and high quality are needed for further verification.
8.New development in the research on FoxO3a and urologic neoplasm
Yuejun TIAN ; Yan TAO ; Qi GUO ; Zhiping WANG ; Mei HONG
Chinese Journal of Clinical Oncology 2015;(15):770-773
The forkhead box O (FoxO) transcription factor family plays an important role in cell functions, including metabo-lism, apoptosis, cellular proliferation, stress reactions, DNA repair, and immune response. As a member of this family, forkhead box O3a (FoxO3a) regulates its target genes by modulating histone modifications, including phosphorylation, acetylation, and methylation. FoxO3a expression is abnormally downregulated in urologic neoplasm. Protein modifications and FoxO3a activity are mainly con-trolled by PI3K/Akt signal pathway and other signaling pathways. FoxO3a is also involved in the initiation, progression, and prognosis of urologic neoplasm. This review focuses on the function of FoxO3a in urologic neoplasm and elucidates the regulatory mechanisms involved. This article will provide novel strategies to clinical diagnosis and drug therapy of urologic neoplasms.
9.Research progress between childhood obesity and breastfeeding
Xueyan ZHANG ; Lei GUO ; Zhiping ZHANG ; Leshan ZHOU
Chinese Journal of Applied Clinical Pediatrics 2014;29(8):635-636
Obesity as a global issue is a serious threat to children's health.To control childhood obesity must begin with effective preventions.Most studies have found that breast milk can protect against childhood obesity.It is recommended that children should be exclusively breastfed for at least 4-6 months.The duration of breastfeeding has some negative correlation with the prevalence of childhood obesity.Increasing the duration of breastfeeding can properly decrease the risk of childhood obesity.
10.Real-time Analgesic Effect of Acupuncture at Shiqizhui (EX-B8) for Primary Dysmenorrhea with Different Needle-retaining Time
Chunmei LIU ; Yuxia MA ; Zhiping GUO ; Chunrong GONG
Shanghai Journal of Acupuncture and Moxibustion 2014;(10):901-902
Objective To treat the patients with primary dysmenorrhea by puncturing Shiqizhui (EX-B8) and observe the change and regularity of the analgesic effect with different needle-retaining time, for providing evidence for the optimal needle-retaining time. Method Ninety eligible subjects with primary dysmenorrhea were randomized into a 20 min group of 30 cases, a 30 min group of 30 cases, and a blank control group of 30 cases. Visual Analogue Scale (VAS) was used to observe the change before and after intervention with the time, and to compare the intergroup differences. Result The acupuncture groups started to show analgesic effect 10 min after needling, and the effect increased with the needle-retaining time (P<0.05);the therapeutic efficacy of the 30 min group was significantly superior to that of the 20 min group (P<0.01). Conclusion Acupuncture at Shiqizhui can produce a real-time analgesic effect for patients with primary dysmenorrhea, and retaining the needle for 30 min is superior to 20 min.