Objective To observe the clinical effect of intra-articular injection of sodium hyaluronate combined with rehabilitation training in treatment of knee osteoarthritis, and their effects on β endorphin and substance P levels in plasma. Methods All 106 cases with knee osteoarthritis were divided into treatment group and control group. Treatment group were treated by intra-articular injection of sodium hyaluronate combined with rehabilitation training, and control group underwent rehabilitation training only. Knee joint function was evaluated using Lysholm scores before and six weeks after treatment, and at 3-month and 6-month follow-up. Meanwhile, the concentrations of β endorphin and substance P in plasma were tested in the two groups. Results Compared with pre- treatment, the Lysholm scores were obviously increased after 6-week treatment, at 3-month and 6-month follow-up in both groups, with more obvious increase in treatment versus control group (P＜0.01). The Lysholm scores were higher in treatment group than in control group (P＜0.01). The concentration of β endorphin in plasma was significantly increased, and the substance P concentration in plasma was decreased after treatment in both groups. There were also significant differences in concentrations of β endorphin and substance P in plasma between treatment group and control group (P＜0.01). Conclusions Intra-articular injection of sodium hyaluronate combined with rehabilitation training is effective in improving knee joint function in elderly patients, in relieving pain and in enhancing joint movement.

BACKGROUND:The post and core system for residual roots and crowns can achieve satisfactory effects, when fil ing restoration, ful crowns or inlay has poor effects. OBJECTIVE:To evaluate the clinical use of glass fiber post and metal post in the restoration of endodontical y treated teeth. METHODS:A total of 106 patients with 160 endodontical y treated teeth were selected and restored with glass fiber post (n=80 teeth) and metal post (n=80 teeth) fol owed by porcelain-fused-mental crown. The restorations were evaluated clinical y for 9 to 33 months. RESULTS AND CONCLUSION:Glass fiber post treatment for 78 teeth was effective and that for two teeth were failed, with a successful rate of 98%. Metal post restoration was effective in 71 teeth and failed in nine teeth including one tooth of crown fracture, four of root fracture and four of post loss, with a successful rate of 89%. There was statistical y significant difference between two groups (P<0.05). Glass fiber post is better in convenient handling and good color and reduced probability leading to root broken for dental restoration compared with metal post.

Obesity is a major risk factor for the prevalence of cardiovascular diseases ( CV D) in China. The application of imaging techniques is helpful to diagnose the visceral fat obesity. A Large number of studies show a positive relationship between the cardiovascular morbidity and obesity. However, there is not a linear correlation between the prognosis of CVD and the degree of obesity, for example, too high or too low body mass index (BMI) or body fat ratio may increase the risk of CVD mortality. The function and type of adipose tissue determine the impact on cardiovascular system, thus, maintaining an appropriate BMI and body fat ratio is beneficial. Besides weight gain control and prevention of cardiovascular events, one goal of antiobesity is to improve the sickness of adipose tissue.

AIM: To investigate the therapeutic effect of Ligustrazine Hydrochloride Injection(LHI) plus Salvia miltiorrhiza Injection(SMI) and LHI plus Ginkgo leaf extract and Dipydamole Injection(GDI) in treating diabetic microalbuminuria. METHODS: 75 inpatients were randomly divided into group SMI(n=35) and group GDI(n=40).Group SMI was treated with LHI 160 mg plus SMI 20 mL intravenous drip daily for 14 days and group GDI with LHI 160 mg plus GDI 20 mL.Their blood samples were collected for measuring glucose,insulin,HbA1c,lipid,creatine and uroacid, and their urine samples for measuring microalbuminuria before and after treatment.The results were statistically(analyzed.)(RESULTS: Before)(treatment,) triglyceride and cholesterol concentrationincreased significantly in group SMI than in group GDI(all P

Objective:To investigate the effective restoration method in penile partial defect.Meth-ods:To measure the thickness of suspensory ligaments on cadavers;To find the relationship between in-ferior pubic ramus and corpora cavernosa crus through corpora cavernosa angiography and ultrasonic scan-ning.The procedure of restoration was based on the use of dissection of the suspensory ligaments and partof crus,and the local fat flap had been transferred to fill the front space of symphysis ossium pubi.Vari-ous flaps were designed as coverage material.Penis residual stump was advanced to anterior portion of thenewly restoration penile body as“glans”;To take full layer skin of penis from post-operating patients toobserve neurofibril regeneration by light microscopy,electron microscopy and scanning electron microsco-py;To determine sensation recovery by physical examination;To check erectile function with NEVA Sys-tem.Results:The whole suspensory ligaments thickness was 7.66cm in average on 30 cadavers(60sides).The crus were attached to bilateral inferior pubic ramus respectively,and distal reached the mid-dle of inferior pubic ramus by corpora cavernosa angiography.In 14 health men by ultrasonic scan-ning,6.60cm in average from root of external penis to location of deep artery penis entered corpora cavernosa.Forty patients had been operated with the above methods.In the cases,the length of the penis variedfrom 0.5-4.0cm in the flaccid,2.0-6.0cm in erect state before operation to 5.0-8.5 cm in theflaccid,7.0-12.5cm in erect state after operation.Twenty-eight cases had been followed up for morethan one year,and 23 patients married with acceptable sexual life,eighteen men had successfully pro-duced their next generations.The regenerative neurofibril could be seen under light microscope,immuno-histochemistry marker,scanning and transmission electron microscope.The penis presented normal painand touch feeling in the post-operating cases.The results showed that there was similar erectile ability ofa normal male in the follow-up patients.Conclusion:With these basic and clinical researches,the resto-ration of penis tends to have a better appearance and function.It's a more optimal method compared withconventional procedures.The results have also provided valuable data for further study in related fields.

asize the strategy of simultaneously modifying all of the risk factors, harmonious equipoise of intervention and tailoring treatment.

Objective To study the efficacy and the influence on immunological function of combination with shenfu and intra-artery chemotherapy for invasive bladder cancer. Methods Group A(36 cases)were treated with shenfu injection and chemotherapy protocol of intra-artery chemotherapy, and group B (30 cases)were treated only with intra-artery chemotherapy. Results The effective rate of group A was higher than group B.And the changes of immunological function,side effects,gastrointestinal response in group A were obviously lower than those in group B(P＜0.05).Conclusions Patients with shenfu injection and intra-artery chemotherapy significant lower influence than those with only intra-artery chemotherapy.The curative effect of shenfu injection and intra-artery chemotherapy is significant.

Objective To explore the clinical characteristics and rehabilitation training of abnormal lateral consonant, namely/l/, of pa-tients with functional articulation disorders (FAD). Methods 107 patients with FAD were observed of the clinical characteristics of/l/. 30 pa-tients with/l/articulation disorder accepted speech training. The correlation and simple linear regression analysis were carried out on/l/ar-ticulation disorders and age. Results The articulation disorder of/l/ mainly showed replacement for/n/,/y/,/r/,/d/ or omission. When/l/combined with vowels contained/i/and/ü/, the main error was omission. When/l/combined with vowels contained/a/,/o/,/e/or/u/, the er-rors trended to be replacement rather than omission. After speech training, the patients made less mistakes about/l/(P<0.001). The frequen-cy of/l/articulation disorders was negatively correlated with age (r=-0.840). The result of simple linear regression analysis showed that the determination coefficient was 0.422. Conclusion The/l/articulation disorder mainly shows replacement or omission, varied with the vow-els. The targeted rehabilitation training may be helpful. Age plays an important role in the outcome of/l/articulation disorder.

[Summary] Clinical studies have confirmed that metabolic surgery is an effective method for the treatment of diabetes ,which can significantly relieve symptoms of type 2 diabetes ,improve various complications and reduce cardiovascular events. Currently ,major limitations of this technique in clinical practice in China include the lack of understanding on surgical benefits ,difficulty in selection of surgery indications and division‐based treatment modalities. Thus ,we should explore a cooperation model of multi‐discipline teams ,understand the mechanisms of type 2 diabetes remission by metabolic surgery and develop physician internist leading standard post‐operation management. These strategies will greatly promote the development of metabolic surgery for type 2 diabetes in China.

Objective To explore the clinical efficacy of adefovir dipivoxil in treatment of liver cirrhosis.Methods 45 cases with liver cirrhosis admitted in 302 Military Hospital of Chian in 2012 were randomly divided into experiment group(n=25)and control group(n=20).Experiment group was treated with adefovir dipivoxil,and control group was given traditional therapy.Two groups were treated for six months.Renal function,liver function and liver firosis were examined with every month,the recovery indexes of renal function between two groups were detected and compared after treatment, which was used to judge the clinical efficacy of adefovir dipivoxil. Results Before treatment,there were no significant differences in the thickness of spleen,serum indexes of portal vein,splenic vein and hepatic fibrosis between experiment group and control group.After treatment,the liver and spleen condition and liver fibrosis index including HA,LN,PCIII,IV-C in two groups were significantly improved by B ultrasound and serum detection,and the improvement degree of experimental group was significantly higher than control group(P<0.05).Conclusion Adefovir dipivoxil has better therapic efficacy in treatment of liver cirrhosis.