Objective To explore the effectiveness of individualized fall prevention strategies in preventing falls among Parkinson's patients.Methods A total of 140 patients with early to mid-stage Parkinson's disease(PD)admitted to our hospital from June 2021 to June 2022 were selected as the study subjects.The patients were randomly divided into a control group and an intervention group using a random number table method,with 70 patients in each group.Both groups received routine and standardised Parkinson's drug treatment.Additionally,the control group received routine fall prevention nursing interventions,while the intervention group received individualized fall prevention plans proposed based on exercise training and health education in addition to the nursing interventions as given in the control group.The two groups were compared in terms of time by timed up and go tests(TUGT)and respective scores by the Modified Fall Effectiveness Energy Scale(MFES),39-item PD questionnaire(PDQ-39),and Berg balance scale(BBS).Results The intervention group presented with significantly shorter TUGT time compared to the control group[(24.90±3.69)s vs.(26.79±3.52)s,P＜0.05].When assessed with the MFES and BBS,the intervention group scored significantly higher compared to the control group[(94.90±9.38)vs.(85.38±8.97),P＜0.05;[(44.37±3.20)vs.(40.52±3.66),P＜0.05,respectively],while,when assessed with the PDQ-39,the intervention group scored significantly lower compared to the control group[(31.13±9.34)vs.(35.25±10.31),P＜0.05].Conclusions Individualized fall prevention strategies proposed based on exercise training and health education can improve their effects on preventing falls of Parkinson's patients and enhance their balance-walking ability,thereby improving their quality of life.Therefore,the strategies are worthy of clinical promotion..

Objective To explore the relationship between type 2 diabetes mellitus(T2DM)and serum stromal cell derived factor-1(SDF-1)levels. Methods A community-based epidemiological field study for T2DM patients and non-T2DM subjects was conducted in Beijing,China. Every subject underwent physical examinations, biochemical tests of stromal cell derived factor 1 and so on,and completed a standardized questionnaire. A total of 756 subjects were recruited in our analysis ,including 267 T2DM patients and 489 non-T2DM subjects ,T2DM patients were further divided into 81 simple T2DM patients and 186 macrovascular complication patients on the basis of the status of macrovascular complication. The correlation between serum SDF-1 levels and T2DM was analyzed. Results Compared with non-T2DM group,the level of SDF-1 in T2DM group was higher(P=0.019). The level of SDF-1 in simple T2DM group was also higher than macrovascular complication group(P=0.044). In the multi-ple linear regression analysis,after adjustment for age,gender,smoking,drinking,dyslipidemia,hypertension and BMI,SDF-1 level in simple T2DM group was higher than macrovascular complication group(P = 0.049), still. Conclusions Simple T2DM patients had a higher serum SDF-1 level than T2DM patients with macrovascular complications as well as those who did not suffer T2DM,suggesting that the stromal cell derived factor-1 may play a certain role in the development of T2DM and macrovascular complications.

Objective: To explore the relationship between glycemic control and visceral adiposity index (VAI) among type 2 diabetes mellitus (T2DM) patients.Methods: A community-based epidemiological field study for patients with T2DM aged ≥ 40 years was conducted in China.Every participant underwent physical examinations, biochemical tests of fasting glucose, glycosylated hemoglobin (HbA1c), total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and so on, and a questionnaire, including anthropometric characteristics, lifestyle, disease history, family history, and medication use.Those participants with HbA1c ≥7.0% were classified as the poorly controlled in our analysis of relationship between glycemic control and VAI.Anthropometric characteristics, lifestyle, and biochemical indexes of the participants were compared among the groups of different VAI levels.Logistic models were applied in multiple analysis adjusting for possible confounders.Results: A total of 1 607 patients with T2DM were recruited in our analysis with a mean age of (59.4±8.1) years and an average T2DM duration of (7.0±6.4) years.Among them, 78.3% were on hypoglycemic therapy.The cutoff points of quartiles of VAI were calculated for the males and females, respectively.According to the ascending order of the quartiles of VAI, the participants were divided into four groups, i.e.Q1, Q2, Q3, and Q4.The poor glycemic control rate for these groups were 60.6%, 65.7%, 70.1%, and 71.0%, respectively (Trend χ2=12.20, P<0.001).After adjustment for age, gender, systolic blood pressure (SBP), diastolic blood pressure (DBP), LDL-C, smoking, cardio-cerebral vascular disease (CVD) history, hypoglycemic therapy, T2DM duration, and family history of diabetes, the Logistic regression models showed that the glycemic control rate was significantly associated with VAI levels among the patients with T2DM.Compared with the participants in group Q1, the ORs of poor glycemic control for those in groups Q2, Q3, and Q4 were 1.239 (95%CI 0.918 to 1.672), 1.513 (95%CI 1.117 to 2.050), and 1.535 (95%CI 1.128to 2.088), respectively (trend P=0.003).With each quartile increase in VAI, the OR of poor glycemic control was 1.162 (95%CI 1.054 to 1.282).Conclusion: The glycemic control among the patients with T2DM is significantly associated with VAI.High level of VAI is an indicator of poor glycemic control.

Objective To explore effect of workshop nursing ward rounds on specialist training for nurse of Neurology Department.Methods Totals of 134 nurses of Neurology Department were randomly divided in two groups, 71 nurses in the intervention group and 63 nurses in the control group. The nurses of intervention group received specialist training based on workshop nursing ward rounds, while the nurse of control group received specialist training of traditional mode. We compared two groups of nurses about disease-related knowledge and patient satisfaction with nursing work.Results The nurses of intervention group have higher scores than the nurses of control group in following aspects: patient's condition (80.8±9.2), implementation of nursing measures (85.9±8.4), and implementation of health education (86.3±8.1) (t=4.015, 7.075, 9.319;P<0.01). The patient's satisfaction in the intervention group was higher than that in the control group (P<0.05).Conclusions Workshop nursing ward rounds in neurology specialist training can make the responsibility system nursing effectively implemented and improve the patient satisfaction.

Objective:To provide Parkinson's patients with health education consultation and personalized rehabilitation programs through the construction and standardized management of Parkinson's care and nursing studio, and to improve the quality of continuous rehabilitation of Parkinson's patients after discharge.Methods:Using the convenient sampling method, 168 patients who attended the Parkinson Care and Nursing Studio in Beijing Tiantan Hospital from April 2018 to June 2019 were selected as the subjects. Parkinson's care and nursing studio was set reasonably, a standardized management system was established, the service objects in the process of diagnosis and treatment were clarified, and the work content of the nursing studio was determined. The Parkinson's care and nursing studio team was led by the head nurse of the Department of Dyskinesia. Multidisciplinary collaboration was adopted, and there were 12 members in this team. An electronic file of the visited patient was established, and the patient's physical function and structure, the individual ability to complete tasks or actions, and the ability to participate in family and society were fully evaluated. Based on this, an objective and individualized rehabilitation training program was developed. Analyze studio workload and patients' satisfacation rate, comepare patient's medication compliance before and after intervention.Results:Since the opening of the Parkinson's Care Studio in April 2018, 12 members have been sent out in rotation, and a total of 168 patients have been treated. Parkinson's nursing care studio has a high evaluation and the very satisfied rate was 95.6%. After the intervention, the patient's medication compliance increased, and the difference was statistically significant before and after the intervention ( P<0.05) . Conclusions:The construction and standardized management of Parkinson's care and nursing studio will help improve the disease management and medication compliance of patients with Parkinson's disease, and it will be beneficial to the improvement of nurses' own value.