1.Effect of Jinyingzi (Rosa laevigata) Aqueous Extract on Urinary System
Yin LU ; Zhiguang SUN ; Huiqi XU
Chinese Traditional and Herbal Drugs 1994;0(10):-
Jinyingzi is the dry ripe fruit of Rosa leav gata Michx.. It contains mainly tannic acid, malic acid, citric acid, vitamin C and saponins. Its effect on urinary sy stem was studied on mouse Pollakiuria model by severing hypogastric nerve. Results showed that the water extract of R. laevigata can decrease the frequency and prolong the interval of urination and increase the quantity of eacn urination. The said extract can inhibit the automatic contraction of isolated rabbit jejunal smooth muscle and antagonize the spasmodic contraction arouscd by acetylcholine and barium chloride of isolated rabbit jejunal smoothmusele, and isolated vesical smooth muscle of mouse, and antagonize reaction of contractility aroused by noradrenalin on isolated thoracic aorta strips of rabbit. All of the the three inhibitions of smooth muscle contraction showed signicant dose-response curve.
2.Model Curricula Development of Clinical Biochemistry
Yibing YIN ; Beizhong LIU ; Zhiguang TU
Chinese Journal of Medical Education Research 2006;0(08):-
As required to the standards of the model curricula and with the years of continuous teaching research and reforming,the clinical biochemistry curriculum has kept developing from the teaching staff,content of course,teaching method and means and the teaching condition etc.,thus forming model curricula with special features and notable results.
3.The exploration and practice of the leading teachers' responsibility system in laboratory medicine course teaching
Wenli FENG ; Yibing YIN ; Yaguang WENG ; Zhiguang TU ; Jianjun ZHU
Chinese Journal of Medical Education Research 2011;10(8):907-909
For the reform and development of clinical laboratory education, based on the previous course reform, Laboratory Medicine College of Chongqing Medical University has put the leading teachers'responsibility system of laboratory medicine course into practice. In the recent 3 years, the course is better organized.The students are more interested in the course and they communicate more with teachers than ever before. The effect of the course is obvious. The leading teachers' responsibility system in laboratory medicine course should be promoted.
4.Construction of national key disciplines and innovative of post-graduate education
Wenli FENG ; Yibin YIN ; Zhiguang TU ; Yaguang WENG ; Jianjun ZHU
Chinese Journal of Medical Education Research 2006;0(07):-
This paper summarizes that to strengthen the construction of national key disciplines Clinical Laboratory Diagnostic and build professional post-graduate education platform for innovation,the exploration and practice of reform have been done in Chongqing Medical University,in the teaching ranks and exercise disciplinary research direction to enhance the level of scientific research and laboratory construction.
5.Exploration and Practice on Teaching Mode of Clinical Practice for the Speciality of Laboratory Medicine
Wenli FENG ; Zhiguang TU ; Yibin YIN ; Hongchu CHEN ; Gefei KANG
Chinese Journal of Medical Education Research 2003;0(02):-
According to the characteristics of the Laboratory Medicine and our twenty years' medical educational experience ,we explore to improve the quality of education and cultivate the students' practical ability and creative ability. And we construct an educational mode for clinical practice, laboratory medical practice and research project.
6.Effect of procyanidins on the release of H_2O_2 induced by croton oil and on lipid peroxidation
Yin LU ; Zhiguang SUN ; Wanzhou ZHAO ; Junshan RUAN ; Xinqi YAN ;
Chinese Pharmacological Bulletin 1986;0(05):-
AIM To study the anti oxidation and cancer chemoprevention mechanism of procyanidins extracted from Vitis vinifera. METHODS A simple colorimetric method is used for the measurement of H 2O 2 produced by PMNs induced by croton oil. RESULTS It was shown that procyanidins could inhibit PMNs releasing H 2O 2 induced by croton oil. Procyanidins serum of rats also had the same effect. The effect was time and dose dependent. Inhibitory effect of procyanidins on hepatic mitochondria lipid peroxidation induced by croton oil was also observed. Procyanidins could raise the activity of SOD and decrease the level of MDA. CONCLUSION It was concluded that anti oxidation effect of procyanidins was one important mechanism of cancer chemoprevention.
8.The application of three-dimensional cell culture technology in the field of cancer research
Yingyu WANG ; Yin LU ; Weiwei ZHANG ; Zhiguang SUN ; Shizhong ZHENG ; Lei CHEN
Chinese Pharmacological Bulletin 2009;25(12):1545-1548
Traditional 2D cell culture technology is widely used in cell culture field, but it lacks the formation of 3D matrix scaffold and lacks specific cytokines in vivo.Cells in 3D cell culture system are similar to cells in vivo for gene expression and cell activity. The article focuses on the application of three-dimensional cell culture technology in cancer research, including the construction of tumor microenvironment,tumor biological behavior, tumor angiogenesis, drug resistance and so on and provides a reference for cancer research workers.
9.Continuous qualitative analysis on paraquat in urine for evaluating the prognosis.
Zhiguang TIAN ; Jie MA ; Yi ZHAO ; Fuhai GAO ; Guangjun WANG ; Yongxiang YIN
Chinese Journal of Industrial Hygiene and Occupational Diseases 2014;32(3):221-222
Adolescent
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Adult
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Aged
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Aged, 80 and over
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Child
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Female
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Humans
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Male
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Middle Aged
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Paraquat
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poisoning
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urine
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Prognosis
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Young Adult
10.Practice of PBL in the teaching of laboratory sciences and clinical medicine
Chunli LUO ; Yibing YIN ; Zhiguang TU ; Wenli FENG ; Min TANG ; Juan ZHANG
Chinese Journal of Medical Education Research 2011;10(6):733-735
It is for estimating the laboratory statistics from the view of clinical medicine objectively,completely and appropriately that we establish < Laboratory Sciences and Clinical Medicine > which fits the requirement for the modern medical laboratory specialists. In this selective course, we use problem-based learning ( PBL ) teaching method which is different from the traditional one, stimulating students to participate in the study actively and passionately,training them to think in a scientific way and to analyse and solve the problem in a rational way. As a result, it works well which makes us believe it is worth popularizing.