Objective:To explore the relationship between dyslipidemia and blood pressure variability (BPV)in pa-tients with essential hypertension.Methods:A total of 251 patients with essential hypertension (EH),who were treated in our department of outpatient from Jan 2011 to Dec 2012,were selected.There were 114 patients with EH complicated dyslipidemia were regarded as EH+dyslipidemia group and 137 pure EH patients reganed as pure EH group.All patients received ambulatory blood pressure monitoring (ABPM);BPV indexes were compared between two groups.Results:Compared with pure EH group,there were significant rise in standard variations (SD)of 24h systolic blood pressure (SBP)and diastolic blood pressure (DBP)[(10.59±2.04)vs.(14.96±4.12),(10.16± 2.11)vs.(12.34±3.19)],24h SBP coefficient of variation (SBPCV)[(0.13±3.07)vs.(0.91±2.21)];daytime (d)SBPSD and DBPSD [(11.27±1.97)vs.(13.98±4.03),(8.94±2.01)vs.(11.34±3.12)],dSBPCV [(0.79±0.21)比 (1.01±0.31)];nighttime (n)SBPSD and DBPSD [(7.96±3.14)vs.(13.22±5.37),(8.13±1.97) vs.(9.95±3.47)],and nSBPCV and nDBPCV [(0.78±0.18)vs.(0.09 ±0.43),(1.07±0.34)vs.(0.13 ± 0.37)]in EH+dyslipidemia group,P <0.01 all.Conclusion:There are relationship between dyslipidemia and blood pressure variability in patients with essential hypertension.