1.Diagnosis and management strategies of small gastrointestinal stromal tumors
Yingjiang YE ; Zhidong GAO ; Shan WANG
Chinese Journal of Digestive Surgery 2013;(4):245-248
The actual incidence of gastrointestinal stromal tumor (GIST) is underestimated.With the progression of awareness and development of examination methods,the detection rate of small GIST (diameter < 5 cm) is increasing year by year.These patients always had no obvious clinical symptoms,and were often detected with small GIST in physical examination unexpectedly.Combination of endoscopic ultrasound and radiographic examination is helpful in detecting small GIST.Aggressive surgical complete resection should be considered in case of a definitive diagnosis.Laparoscopic resection is becoming the standard surgical treatment currently.For micro GIST (diameter <2 cm),especially micro gastric stromal tumor,current guidelines recommend close observation.Some scholars advocate that endoscopic resection is feasible for the treatment of micro GIST,while we think that the efficacy of individualized treatment is better after identifying the potential malignancy of micro GIST.
2.Clinical Effect of Renal Artery Embolization for Renal Graft Dysfunction
Zhihao YANG ; Zhidong YE ; Peng LIU
Chinese Journal of Minimally Invasive Surgery 2001;0(04):-
Objective To explore the clinical effect of renal artery embolization for renal graft dysfunction.Methods A total of 17 patients with renal graft dysfunction were treated by embolizing the renal graft artery.Coil embolization was performed on 7 of the cases,and gelfoam combined with coil was used in the other 10.Results Among the 17 patients,14 discontinued immunosuppressant in 3 weeks after the embolization,and 2 discontinued after receiving low-dose cortisones for about 6 months,and showed good recovery during follow-up.The other patient underwent resection of the renal graft because of continuous fever and graft pain.After the embolization,14 cases developed 'post-embolization syndrome'.Coil migration occurred in 1 case during the procedure.One patient experienced angina during the operation,and developed myocardial infraction the day after the embolization.Conclusions Renal artery embolization is safe and effective for patients with renal graft dysfunction.By using the method,open surgery can be avoided.Attention should be paid to potential complications.
3.The change of cardiac structure and function in the Patients with type 2 diabetes mellitus
Zhidong YE ; Xingduan GUO ; Junhai LIU ; Ling ZHANG
Chinese Journal of Primary Medicine and Pharmacy 2008;15(2):200-201
Objective To explore the changes of cardiac structure and funetion in the patients with type 2 diabetes mellitus(T2DM).Methods Thirty T2DM patients were included in the study,color Doppler echocardiography was performed in all of the cases,to compare and analyze the results of cardiac structure and function.Results IVS,LVPW,LAD,LVM of T2DM group were significantly larger than those in healthy group(P<0.05,P<0.01).T2DM group of LVEF and E/A ratio were significantly lower than those of normal group(P<0.05).BMI,FBG,TG were positive correlation with IVS,LVPW,LVM and negative correlation with LVEF,E/A.Conclusion The patients of T2DM can lead to change of cardiac structure and function which dependent with BMI and glucose degree.
4.The retention of the great saphenous vein below-knee decreases saphenous nerve injury during varicose veins surgery
Gaolei JIA ; Zhidong YE ; Peng LIU ; Yanan ZHEN
Chinese Journal of General Surgery 2013;28(11):865-867
Objective To evaluate selective retention of the great saphenous vein (GSV) belowknee in the prevention of saphenous nerve injury during varicose veins surgery.Methods From January 2009 to January 2012,280 consecutive patients with incompetence of the GSV resulting in varicose veins were prospectively randomized into 2 groups.Patients in the experimental group underwent stripping restricted to the below knee level,patients in control group underwent GSV stripping to the ankle level Patients in the two groups were treated with transilluminated powered phlebectomy,and foam sclerotherapy.Primary end points were postoperative pain,saphenous nerve injury,quality of life and recurrence rate.Results After one month follow-up:5.71% patients had symptoms of nervous system in the observation group,14.29% patients had symptoms of nervous system in the control group (P =0.02).After 1 year follow-up,1.47% patients had symptoms of nervous system in the observation group,7.14% patients had symptoms of nervous system in the control group (P =0.02).Conclusions Selective retention of great saphenous vein below-knee decreases saphenous nerve injury.
5.Complications after carotid artery stenting in patients with carotid artery stenosis
Zhidong YE ; Jie CHEN ; Xueqiang FAN ; Fei WANG ; Peng LIU
Chinese Journal of General Surgery 2012;27(7):531-534
Objective To analyze complications of carotid artery stenting (CAS) and preventions.Methods Clinical data and treatment outcomes of 72 consecutive patients ( 80 stents ) from July 2006 to January 2012 with carotid stenosis were analyzed.Asprin 100 mg and clopedigrel 75 mg were given orally 5 days before CAS.Distal embolic protection device were implanted in all patients,pre-dilatation was done for those with carotid stenosis > 90% and post-dilatation was done for those of residual stenesis > 30%.Severe complications of CAS mean death,myocardial infarction (MI) and stroke.Other minom included transient ischemic attack ( TIA ),hyperperfusion and intracranial hemorrhage ( ICH ),bradycardia and/or hypotension,hypertension,access hematoma or bleeding.Results In 72 patients a total of 80 self-expandable bare stents were successfully implanted.Distal embolic protection devices were used in all cases.Combined procedure was taken in 5 cases including OPCABG in 2 cases,left subclavain artery stenting in 2 cases and renal artery stenting in 1 case.The overall in-hospital complications was 37.5% (27 of 72).Of these events,1 case had minor strokes defined as a modified Rankin Scale score less than 3 at 1-year follow-up,2 patients (2.78% ) experienced a hemispheric TIA (neurological symptoms that resolved within 24 hours),1 patient experienced hyperperfusion syndrome.The overall mortality rate was 0,21 cases (29.2% ) experienced hemodynamic instability (hypotension in 15 cases,bradycardia in 5 cases and hypertension in 1 case) and 2 others had access hematoms.The 30-day death/stroke/myocardial infarction risk was 1.39% (1 minor stroke).Conclusions Hemedynamic instability (hypotension and bredycardia) is main complications of carotid artery stenting in patients with carotid artery stenosis,severe complications are rare.
6.A comparative study of revascularization treatment for patients with iliac artery occlusion vs stenosis
Jianbin ZHANG ; Rongwei XU ; Peng LIU ; Yanan ZHEN ; Zhidong YE
Chinese Journal of General Surgery 2016;31(4):301-304
Objective To compare the outcome and early patency rate of revascularization treatment for patients with iliac artery occlusion or stenosis.Methods Retrospective analysis was made on 105 cases of iliac artery occlusion or stenosis from January 2009 to April 2014.49 were with iliac artery occlusion and 56 with iliac artery stenosis.Results The demographics,and comorbidities were not statistically different between the 2 groups.The occlusion group had more critical limb ischemia and the ankle-brachial index was lower than the stenosis group.The occlusion group underwent more hybrid surgery and used more covered stents in the operation.The peri-operative complication was higher in the occlusion group,but the difference was not statistically different.The ABI improved significantly for all patients after surgery.The early patency rate was similar in the 2 groups.Conclusions Revascularization treatment for patients with iliac artery occlusion and stenosis was safe and effective,with similar early patency rate and peri-operative complications between the two groups.
7.Anatomical structures relevant to complete mesocolic excision: mesentery, fascia and space.
Chinese Journal of Gastrointestinal Surgery 2016;19(10):1084-1087
Anatomy is the foundation of surgical techniques. With the development of surgery, anatomy also divided into traditional anatomy, surgical anatomy and embryonic development anatomy. Complete mesocolic excision (CME) is one of classic radical operation for colon cancer, based on the modern anatomy. CME advocates correct operation plane, and describes the mobilization and separation of the colon together with the entire regional mesocolon. With the evolution of anatomy, the definition and content of CME-related anatomic landmarks such as mesentery, fascia and space have been changed. This article elaborates theses anatomical structures and their distribution, in order to improve the understanding of colorectal surgeons on CME-related traditional anatomy, surgical anatomy and embryonic developmental anatomy.
Colectomy
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Colonic Neoplasms
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surgery
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Digestive System Surgical Procedures
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Fascia
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anatomy & histology
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Fasciotomy
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Humans
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Mesentery
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Mesocolon
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anatomy & histology
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surgery
8.Endovenous laser treatment,radiofrequency endovenous occlusion and conventional stripping combined with transilluminated powered phlebectomy for lower extremity varicose vein
Peng LIU ; Zhidong YE ; Xueqiang FAN ; Fei WANG ; Fan LIN ; Desheng CAO ; Yuguang YANG ; Fenglin WANG
Chinese Journal of General Surgery 2008;23(3):171-174
Objective To compare the clinical results of endovenous laser treatment(EVLT),radiofrequency endovenous occlusion(RFO)and conventional stripping combined with transilluminated powered phlebectomy(TIPP)for lower extremity varicose vein.Methods From Jun 2004 to Jan 2007,200 cases(232 limbs)were treated by EVLT with TIPP,80 cases(88 limbs)by RFO with TIPP,and 180 cases(202 limbs)by conventional stripping with TIPP.Operation time,number of the incision made,intraoperative bleeding,postoperative hospital stay,complications,and one-year recurrence rate were compared with each other. Results Operation time was longer(41±8)min in RFO group than that in other two groups.Postoperative hospital stay was shorter in EVLT group(1.2±0.4 d)and RFO group (2.1±0.8 d)than that in stripping and TIPP group(P<0.05).Patients in stripping group also suffered from more intra-operative bleeding more often incidental nervus saphenus injury and more incision numbers when compared with other two groups(P<0.05).There was no significant difierence in one-year recurrence rate among patients in the three groups. Conclusions The clinical efficacy is almost the same among the three groups in terms of eradication of the varicose veins.EVLT and RFO are safe and minimal invasive for the treatment of lower extremity varicose vein.
9.Bio-artificial dura mater versus autogenous periosteum for Substituting dura mater
Zhidong SHI ; Mingwang LIU ; Zhongzong QIN ; Qinmei WANG ; Ying GUO ; Zhuopeng YE ; Zhonghe YU
Chinese Journal of Tissue Engineering Research 2007;11(40):8201-8204
BACKGROUND:At present,autogenous periosteum and artificial dura mater are usually applied as the substitute grafts for the dural defect by neurological surgery.However they do not accord with the developing trend of modern medicine,due to the limitations of material size and shape,operational complex and additional wound.OBJECTIVE:To observe and compare the evolution of a new type bio-artificial dura and autogenous periosteum in replacing orthotopic duraDESIGN:Controlled observation and trial.SETTING:Animal Testing Center in the 157 Hospital of Guangzhou City.MATERIALS:Nine New Zealand rabbits.aged 6 months and weighed 2-3 kg,either gender was selected.Twelve hybrid healthy dogs of both genders,aged 2 years and weighed 15-20 kg.New type dura mater(No.2006.3460627).METHODS:The experiment was carried out at the Animal Testing Center in the 157 Hospital of Guangzhou City from October 2003 to October 2005.After the general anesthesia and bilateral craniotomy,the bilateral dural defect and pia mater injury were induced partly,then dural neoplasty was performed using new type artificial dura and autogenous periosteum.MAIN OUTCOME MEASURES:At months 1,6,12 of modeling,each three rabbits were selected to isolate and expose the implanted materials,while each four dogs were selected at months 6,12,24 of modeling,died of disease or prior to death.General observation and microscopic assessment of samples were compared to analyze the development of implanted materials at difference stages.RESULTS:Except one experimental dog died during the anesthesia,9 rabbits and 11 dogs were involved in the final presented the extemal surface of adherence and separation with pedcranium,grew well with surrounding orthotopic dura.For the internal surface of materials,the new type artificial dura was more likely the orthotopic dura and did no adhere to pericranium, and filament-shaped adherence appeared occasionally, while there were filament-shaped even month 12 of grafting new type artificial dura into the experimental rabbits.inflammatory cellular reactions such as neutrophil and lymphocyte were not found,additionally no capsule wall formation occurred.The internal surface of artificial dura was covered with epithelial cells,which appeared fibroplasia,fibroblast proliferation,degradation of implants and obvious reduction of total cell amount.Moreover the blood capillary was also found.CONCLUSION:New type artificial dura can achieve the dural reconstruction through producing epithelial cells and being nibbled.degraded and substituted by autogenous tissue.And no adherence to cerebral tissues is found.New type artificial dura is superior to autogenous periosteum for repairing the dural defects.
10.Surgical therapy of postoperative recurrent varicose veins
Jie CHEN ; Zhidong YE ; Xueqiang FAN ; Jiangtao LIU ; Fei WANG ; Fan LIN ; Peng LIU
Chinese Journal of General Surgery 2014;29(4):253-256
Objective To summarize the etiologic factors and evaluate the clinical outcome of reoperations on 119 limbs of recurrent varicose veins.Methods Retrospective analysis was made on etiologic factors of 119 limbs (113 patients) of recurrent varicose veins admitted to our hospital from January 2007 to June 2013.All patients underwent color duplex ultrasonography and anterograde venography of the lower extremity and were treated by reoperations.Results In the 119 limbs,102 limbs (85.7%) had residual main great saphenous veins or tributaries,97 limbs (81.5%) had incompetent perforator veins,23 limbs (19.3%) had neovascularization,9 limbs (7.6%) had incompetent small saphenous veins,21 limbs (17.6%) had incompetent femoral veins,6 limbs (5.0%) had iliac vein compression syndrome,and Budd Chiari syndrome was found as the cause of recurrence in 1 limb (0.8%).Postoperative patients were followed-up for 6-72 m (32-± 7 m).The cure rate of varicose veins were 100%.There was not recurrence of varicose veins,postoperative VCSS was 0-5 (1.2 ±0.5) vs preoperative 1-17 (6.2 ±2.5)(P < 0.01).Conclusions Residual and incompetent great saphenous veins or tributaries and incompetent perforator veins were the main etiologic factors of postoperative recurrent varicose veins.Therapeutic principle for recurrent varicose veins is to eliminating the reverse flow of superficial vein system and ligate incompetent perforator veins.