1.Prevention and treatment of vaginal bleeding after drug-induced abortion by Yaoliuan capsule and its effects on menses recovery.
Zhichun, JIN ; Guangying, HUANG
Journal of Huazhong University of Science and Technology (Medical Sciences) 2005;25(3):346-7, 367
In order to explore the effect of Yaoliuan capsule in the prevention and treatment of vaginal bleeding after drug-induced abortion and menses recovery after drug-induced abortion, 323 cases of gestation period < or = 49 days and without contraindication, were divided randomly into study group (168 cases, taking Yaoliuan capsule) and control group (155 cases, taking placebo capsule). The results showed that in the study group, there were 161 cases (95.8%) of complete abortion, 7 cases (4.2%) of incomplete abortion; In the control group, there were 146 cases (94.2%) of complete abortion, 6 cases (3.9%) of incomplete abortion, 3 cases (1.9%) of abortion failure. The vaginal bleeding time was 5-25 days (mean 10.8 days) in study group, while that was 6-62 days (mean 19.1 days) in control group. The menstrual cycle was 30.5+/-5. 2 days and 33.8 d+/-8.6 days respectively in study and control groups. The menstrual period was 6.1+/-3. 5 days and 9.9+/-5.1 days respectively in study and control groups. Yaoliuan capsule is an effective drug to prevent and treat vaginal bleeding following drug-induced abortion, promote menstruation recovery and prevent pelvic infection.
Abortifacient Agents, Nonsteroidal/adverse effects
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Abortion, Induced/*adverse effects
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Capsules
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Drugs, Chinese Herbal/*therapeutic use
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Menstruation/*drug effects
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Phytotherapy
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Pregnancy Trimester, First
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Uterine Hemorrhage/etiology
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Uterine Hemorrhage/*prevention & control
2.The correlation between patent ductus arteriosus and B-type natriuretic peptide as weel as N-terminalpro-brain natriuretic peptide in preterm infants
Min HUANG ; Zhichun FENG ; Jia CHEN
Chinese Journal of Applied Clinical Pediatrics 2015;30(10):793-795
Patent ductus arteriosus(PDA) is a common condition that primarily occurs in preterm infants who with low birth weight,which closely related to several co-morbidities(intracranial hemorrhage,necrotizing enterocolitis,pulmonary edema/hemorrhage,bron chopulmonary dysplasia,and retinopathy).Although the color Doppler ultrasound assessment can be used as the gold standard to determine the present of PDA,it is still very hard to fully reflect the hemodynamic change occured in PDA case.In recent years,B-type natriuretic peptide (BNP) and N-terminal pro-brain natriuretic peptide (NT-proBNP),two kind of biological markers,were used in the premature infants to assess the present,shunt volume,progress and durg or surgical intervention indication of PDA.In this paper,the corrections of PDA between BNP and NT-proBNP were reviewed briefly.
3.Study of the reconstruction methods after vertical partial laryngectomy for glottic carcinoma of the larynx
Fengbing ZHANG ; Zhichun HUANG ; Yincheng CAO
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2001;(6):249-250,252
To study the reconstruction methods after vertical partial laryngectomy for glottic carcinoma of the larynx. Method:58 cases with glottic carcinoma of the larynx were treated with vertical partial laryngectomy or extended vertical partial laryngetomy .The clinical materials of these cases were retrospectively studied.Result:The total decannulation rate was 93.1% and the 3-and 5-year survival rates were 87.2% and 80.5% respectively .The voice was socially acceptable in 93.1%(54/58) of the patients. Aspiration was only 3. All resumed mouth-food-taking.Conclusion:The reconstruction methods after vertical partial laryngectomy were mainly decided by the extent of the laryngeal defect. If the laryngeal defect of the framework was small, the pedicle muscular flap was the best reconstruction method in comparison with other reconstruction methods .If the laryngeal defect of the framework was too big ,allograft nasal septal cartilage or epiglottic laryngoplasty should be performed .
4.The value of reference about microvolt T-wave alternans test in Chinese.
Zhichun HUANG ; Yuan XU ; Jihong GUO
Chinese Journal of Practical Internal Medicine 2003;0(01):-
1.9?V and 95% confidence interval was 1.52-2.41?V.There was significant differences among the groups(P
5.Phonomicrosurgery for Reinke's Edema of the Vocal Fold
Xu FENG ; Fengbing ZHANG ; Zhichun HUANG
Chinese Journal of Minimally Invasive Surgery 2001;0(05):-
0.05).The jitter(q=27.885),shimmer(q=35.839),NNE(q=5.817),and harmonic noise ratio(HNR,q=6.383)decreased significantly at 1 month after the operation(P
6.Modified uvulopalatopharyngoplasty for treatment of obstructive sleep apnea hypopnea syndrome
Xin ZHU ; Zhichun HUANG ; Xu FENG
Chinese Archives of Otolaryngology-Head and Neck Surgery 2006;0(12):-
OBJECTIVE To investigate the therapeutic effect of modified uvulopaoatopharyngoplasty(UPPP)on obstructive sleep apnea hypopnea syndrome(OSAHS).METHODS Sixty eight cases of OSAHS were treated with modified UPPP.During operations,the uvula was preserved,the fat tissues of space veli palatine were dissected,palatoplasty and pharyngoplasty were performed.All the patients were followed up for over 6 months.Polysomnography(PSG)was monitored again one year after operation.RESULTS The symptoms of dyspnea,snoring,sleepiness were disappeared or improved obviously after 6 months.The effective rate was 95.6% at one year after operation.CONCLUSION The modified UPPP not only extends the oropharyngeal cavity,but also avoids postoperative complications and improve the effectiveness of UPPP.
7.An Experiment of Using Nitinol Alloy Momemorial Stent to Treat the Stenosis of the Rabbi
Mengdong WANG ; Zhichun HUANG ; Jianxing GU ; Baobin SUN ; Xu FENG
Journal of Audiology and Speech Pathology 2010;18(2):170-172
Objective To compare the effects of nitinol alloy memorial stent with silastic tube in treating the stenosis of the rabbit.Methods 16 rabbits with external ear canal(EEC) stenosis were randomly divided into two groups.One group was implanted with skin on the EEC wound while the other not.By self-comparison method nitinol alloy memorial stem was implanted in a rabbit's one ear and the silastic tube in the other.After days 5,15,30,and 60 later,the diameters of the external ear canal (with two materials planted) were measured respectively in the skin-planting group.In the naked group scar tissues were harvested and tested separately according to the planting material.HE coloration were used to study fibroblast hyperplasty while RT-PCR were applied to detecting the TGFβ1mRNA expression.The two brackets were compared according to their effect to scar hyperplasty.Results The EEC diameters using nitinol alloy memorial stem were found more spacious than using silastic tube.HE coloration showed the fibroblast hyperplasia was more mitigatory by using the nitinol alloy memorial stent.RT-PCR also found the TGFβ1mRNA expression was low by using same material.Conclusion The nitinol alloy memorial stent shows obvious superiority over silastic tube in external ear canal stenosis therapy.
9.Analysis of Klebsiella pneumoniae infection in 75 preterm infants
Shaodong HUA ; Qiuping LI ; Jieting HUANG ; Zhixin WU ; Zhichun FENG
Chinese Journal of Perinatal Medicine 2012;15(2):95-100
Objective To analyze the clinical characteristics of Klebsiella pneumoniae infection in preterm infants. Methods Clinical data of 75 preterm infants infected with Klebsiella pneumoniae treated in BaYi Children's Hospital from February 6,2008 to February 10,2010 were retrospectively analyzed.The difference of auxiliary examination between early-onset and late-onset infection group were compared by two independent samples t test.Spearman correlation analysis and non-conditional Logistic regression analysis were used to analyze the high risk factors and the prognostic factors of Klebsiella pneumoniae infection in preterm infants. Results The incidence of Klebsiella pneumoniae infection was 2.8% (75/2721) in preterm infants,and the mortality rate was 9.3% (7/75). There were 71 cases of Klebsiella pneumoniae sepsis and 4 cases of Klebsiella pneumoniae pneumonia.Among 75 cases,63 cases were early-onset infection (onset age≤72 h) and 12 were late-onset infection (onset age>72 h).All patients presented with poor response,heart rate during quiet sleep > 160/min and low oxygen saturation.The mean corpuscular volume and mean corpuscular hemoglobin concentration in early-onset Klebsiella pneunoniae infection cases were higher than those in late-onset neonates [(128.87±24.60) fl vs (113.72±13.54) fl,t=-2.07,P<0.05and (38.11±2.15) pg vs (36.98±1.05) pg,t=-2.76,P<0.05].Low birth weight and caesarean section were associated with early-onset Klebsiella pneumoniae sepsis (r=0.250 and -0.240,P<0.05). The prognosis of Klebsiella pneumoniae infection was associated with hospital stay and duration of premature rupture of membranes (r=0.368 and 0.318,P<0.05). Conclusions There were no specific clinical manifestations for Klebsiella pneumoniae infection in preterm infants.Preterm infants with low birth weight,long duration of premature rupture of membranes,delivered by caesarean section and received invasive operation are likely to develop Klebsiella pneumoniae infection.
10.Clinical observation of the application of dezocine combined with fentanyl in high intensity focused ultrasound in the treatment of uterine fibroids
Dongmei YAO ; Shuijuan ZHANG ; Yanming HUANG ; Aiguo ZHANG ; Zhichun JIN
Chongqing Medicine 2015;(2):189-191
Objective To observe the feasibility of combining dezocine with fentanyl in the application of single integral high in‐tensity focused ultrasound(HIFU)ablation of uterine fibroids .Methods One hundred and sixty patients with uterine fibroids trea‐ted by HIFU under conscious sedation were randomly divided into 2 groups(n=80):group A with treatment combined fentanyl and midazolam and group B treated with combined dezocine ,fentanyl and midazolam .Analgesic effect was evaluated with visual analog scale (VAS) .Variation of patients′vital signs (blood pressure ,heart rate ,electrocardiogram ,oxygen saturation) ,pain scores ,com‐fort scores ,sedation scores ,analgesic consumption and side effects were recorded before treatment (T0 ) ,during drug delivery (T1 ) , at the beginning of the treatment(T2 ) ,30 minutes after drug delivery (T3 ) ,at the end of the treatment(T4 ) ,2 hours after treatment (T5 ) ,4 hours after treatment (T6 ) ,8 hours after treatment (T7 )and 24 hours after treatment(T8 ) .Results Both groups showed reliable analgesic effects and vital signs of each time point were stable .VAS scores and Ramsay scores of group A were higher than those of group B ,but there was no statistical difference (P>0 .05) .Three patients in group A showed dysuria and relieved after symptomatic treatment .No respiratory depression occurred in both groups .But compared to group A ,the incidence of the analgesic side effects of group B was significantly lower and patients satisfaction was significantly higher(P<0 .05) .Conclusion The analge‐sic effects of dezocine combined with fentanyl are reliable in HIFU ablation of uterine fibroids with fewer side effects ,and could be worthy to be promoted in clinical use .