1.The diagnostic value of microalbuminuria in early diabetic nephropathy
Journal of Chongqing Medical University 1986;0(04):-
Objective:To study the significance of microalbuminuria in the diagnosis of early diabetic nephropathy.Methods:24 hour urine ? 1-microglobulin(? 1-MG),urine immunoglobulin G(IgG),urine microalbumin (MA) and urine transferrin(TRF) in 65 diabetic patients and 50 normals were detected by rate immunonephelometery method.Results: The urine MA in 65 diabetic patients was significantly higher than that in 50 healthy persons ( P
2.Several Problems during the Diagnosis and Treat of Orthopedical diseases
Chinese Medical Ethics 1995;0(02):-
This article disusses several ethical problems between patients and doctors from patients' entering into the hospital to the whole course of diagnosis and treat,meanwhile it brings forward some elementary countermeasures.In order to promote the development of orthopedical surgeons and orthopedics,it makes everybody familiar with ethical problems during the diagnosis and treat of orthopedical diseases
3.Influence of smoking on the occurrence and development of age-related macular degeneration
Chinese Journal of Experimental Ophthalmology 2021;39(1):93-96
Age-related macular degeneration (AMD) causes vision loss mainly due to apoptosis of retinal pigment epithelium cells and subsequent degeneration of photoreceptors.Active and passive smoking can increase the incidence of AMD and the progression risk of advanced AMD, and affect the treatment effect of wet AMD.Smoking can cause choroidal vasoconstriction, increased vascular resistance, vascular endothelial dysfunction, thinned choroid and ganglion cell complexes, resulting in impaired vascular reactivity of choroid and retinal vessels.Nicotine in cigarettes can lead to the overexpression of vascular endothelial growth factor (VEGF), which increases the permeability of vessel and proliferation of endothelial cells, thus induces the formation of choroidal neovascularization (CNV). Smoking can induce oxidative stress leading to oxidative damage, reduce the expression of complement factor H, increase the membrane attack complex, lead to macrophage dysfunction, promote the formation of drusen, and induce the formation of CNV.Therefore, a full and deep understanding of the relationship between smoking and CNV and AMD in controlling the occurrence of AMD and preventing the formation of CNV is of great significance for the early prevention of AMD and the exploration of more effective treatment approaches.
4.Clinical Observation of the effect of Shenmai injection on congestive heart failure
Chinese Journal of Primary Medicine and Pharmacy 2010;17(15):2079-2080
Objective To observe the effect of Shenmai injection on congestive heart failure(CHF) and the effect on thyroid hormone as well as medicine security. Methods 52 patieits with CHF were enrolled,Shenmai injection was used with regular western medicine in the treatment. And observed its effect and test serum thyroid hormone: TSH,T3 ,T4 ,rT3. Another 50 CHF patients were enrolled as a control. Results The results of observation were that 25 cases were very effective,23 were effective,4 had no effect and the total effective rate was 92%. The results of control group were that 21 were very effective, 16 were effective, 13 had no effect and the total effective rate was 74%. The differences between the two groups were significant (P > 0.05). By comparing two thyroid hormone T3, T4, rT3, the observation T3 and T4 was obviously higher than the control. rT3 was lower than the control. Conclusion Shenmai injection could efficiently improve the heart function of CHF,cure arrhythmin and correct the illness caused by thyroid hormone.
5.107 examples cervical carcinomas clinical analysis
Shenghong ZHANG ; Zhicheng YANG
Cancer Research and Clinic 2005;0(S1):-
Objective To research diagnosis and treatment of different state of cervical carcinoma. Methods To sum up clinical experience of pathogeny, diagnosis and treatment from 107 patients with diferent state of cervical carcinoma. Observe the 5 year survival rate from thease patients. Results Aim at the inducement of cervical carcinoma that to develop the general examination of gynecology disease can find out,treat and prevent the high dangerous patients early. And it can decrease the occurrence and improve the therapeutic efficacy of cervical carcinoma. The stagement of cervical carcinoma will effect the 5 year survival ratdirectly. Choose correct therapeutic method will improve the rate. Conclusion Find out cervical carcinoma early is impotent to improve the therapeutic efficacy and the 5 year survival rate. We should develop the general examination of gynecology disease and health education widely to ensure the health of immense women's body and mind.
6.Evaluation and clinical application of the subaxial cervical spine injury classification system
Tiansheng SUN ; Zhicheng ZHANG
Chinese Journal of Trauma 2009;25(5):403-407
Objective To evaluate the interobserver reliability and intraobserver reproducibility of the subaxial cervical spine injury classification system (SLIC) and identify its guidance on clinical treatment of spinal cord injuries. Methods Thirty consecutive patients with subaxial cervical injury ad-mitted into our hospital between December 2007 and July 2008 were enrolled in this study and underwent neurological examinations followed by X-ray, CT, and MRI examinations. SLIC was evaluated in aspects of fracture morphology, disco-ligamentous complex (DLC) status and ncurologic status. According to the morphology in image, the fractures were classified into normal, compression, burst, distraction and trans-lation/rotation. According to injury severity, DLC was sorted into intact, indeterminate and disrupted types. Neurologic status was classified into intact, nerve root injury, complete/incomplete spinal cord in-jury and continuous spinal cord compression. The clinical and radiographic data of 30 patients with subax-ial cervical injury were evaluated prospectively by four groups of surgeons to count SLIC scores and decide treatment based on SLIC scores. The evaluation was done again three months later. Cohen' s unweighted kappa coefficients were calculated for the key parameters of each classification system ( morphology, neurologic status, DLCstatus, total score, and proposed management) to analyze the reliability and repreducibility of SLIC. Based on SLIC, the treatment method was selected and the neurological function recovery and the complications observed. Results The interrater Kappa statistics of all subgroups ( morphology, DLCstatus, total score, proposed management) were within the range of moderate to substantial reliability (0.47-0.69). Kappa coefficient was 0.83 for neurologic status, with high reliability. There was no statistical difference upon Kappa values in two evaluations. The interrater Kappa statistics of all sub-groups ( morphology, DLCstatus, total score, proposed management) were within the range of moderate to substantial reproducibility (0.53-0.78). Kappa coefficient was 0.89 for neurologic stares, with high repreducibility. The recovery rate of neuroiogie function was 79.2%. There was no aggravation of neurological status, with low incidence of complications. Conclusions SLIC has advantages of high reliability and reproducibility, simple use, exact evaluation and can facilitate decision-making in treatment of subaxial cervical spine injures.
7.Clinical significance of cytomegalovirus detection after kidney transplantation
Zhicheng ZHANG ; Shaoli DENG ;
Journal of Third Military Medical University 2003;0(09):-
Objective To investigate the significance of the detection of cytomegalovirus (CMV) infection after kidney transplantation. Methods The serum CMV antibody(anti CMV) and CMV DAN of 72 recipients before and after transplantation were detected respectively by enzyme linked immunosorbent assay(ELISA) and polymerase chain reaction(PCR). Results The levels of serum CMV antibody and CMV DNA of 72 recipients after transplantation were significantly higher than those of pre operation( P
8.Pollution Status of Giardia lamblia and Cryptosporidium parvum in the Centralized Water Supply Enterprises,Shenzhen,2008
Zhicheng ZHANG ; Shuyuan YU ; Renli ZHANG
Journal of Environment and Health 1993;0(01):-
Objective To investigate water treatment technology and pollution status of Giardia lamblia and Cryptosporidium parvum in resource water and finished water of the centralized water supply enterprises in Shenzhen,and to provide scientific basis for waterborn infectious disease control.Methods Field hygiene assessment were conducted on the resource water and water treatment technology of 19 water supply enterprises during May to July,2008.One water sample was collected from resource water and finished water in each centralized water supply enterprise respectively,and was detected for Giardia lamblia and Cryptosporidium parvum.Results The routine traditional water treatment technology including coagulation deposition,quartz sand filtration and chlorine disinfection was applied in all of the 19 centralized water supply enterprises.Giardia lamblia and Cryptosporidium parvum were not found in samples from the source water and finished water.Conclusion The centralized water supply system in Shenzhen isn't polluted by Giardia lamblia and Cryptosporidium parvum.
9.Troubleshooting for Carestream GC1.5 Workstation.
Liangning YU ; Junjie ZHANG ; Zhicheng YANG
Chinese Journal of Medical Instrumentation 2015;39(6):463-466
This paper is maintenance of four kinds of failures of Carestream GC1.5 the workstation used several years to summarize, workstation software, change the host, burn, workstations transmission, and four kinds of failures of the specific case of itemized elimination steps are introduced.
Computers
;
standards
;
Maintenance
;
Software
10.A clinical study on reconstruction and suture repair medial patellofemoral ligament in the treatment of patellar dislocation
Xiucheng CHU ; Zhicheng ZHANG ; Lianmin WEI
Chinese Journal of Postgraduates of Medicine 2014;37(8):33-36
Objective To explore the operation effect of isometric reconstruction of the medial patellofemoral ligament with the semitendinosus tendon and direct suture rehabilitation of the medial patellofemoral ligament in the treatment of patellar dislocation,and provide some reference for the surgical treatment of this disease.Methods Forty patients with patellar dislocation included 20 patients with suture repair (suture group) and 20 patients with reconstruction (reconstruction group).The erythrocyte sedimentation rate,C-reactive protein were determined at 3,14 d after operation in two groups.The congruence angles (CA),lateal patellofemoral angle (LPA),lateral patellar displacement(LS) before and after operation,knee joint function,efficacy after operation were observed and compared.Results There was no significant difference in CA,LPA,LS between two groups (P > 0.05).CA,LPA,LS after operation were improved compared with before operation in two groups [suture group:(9.13 ± 1.88)° vs.(16.50 ±2.83)°,(8.48 ± 1.19)° vs.(-1.28 ± 2.12)°,(0.52 ± 0.43)° vs.(0.78 ± 0.32)° ;reconstruction group:(6.69 ± 1.83)° vs.(16.95 ±3.17)°,(6.24 ± 1.33)° vs.(-0.91 ±2.00)°,(0.32 ±0.23)° vs.(0.70 ±0.16)°],and there was significant difference (P< 0.01).The improvement of CA,LPA,LS in reconstruction group were better than that in suture group,and there was significant difference (P< 0.01).The knee joint function score by Lysholm was (38.27 ± 17.06) scores in suture group,(79.44 ±9.86) scores in reconstruction group,and there was significant difference (P < 0.05).There was no significant difference in the erythrocyte sedimentation rate,C-reactive protein at 3,14 d after operation between two groups (P >0.05).Conclusions The operation effect of isometric reconstruction of the medial patellofemoral ligament with the semitendinosus tendon method is better than the direct suture rehabilitation of the medial patellofemoral ligament method,the former can effectively restore the relationship between patella and femoral trochlea,and cure the dislocation of patella from the root.